CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 27 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
23
With full pages
9
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1ccc(NS(=O)(=O)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1ccc(NS(=O)(=O)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-Methyl-N-(4-(2-(4-methylbenzylidene)hydrazine-1-carbonyl)phenyl)benzenesulfonamide chemical structure, C22H21N3O3S, CAS 389126-19-6
N-Methyl-N-(4-(2-(4-methylbenzylidene)hydrazine-1-carbonyl)phenyl)benzenesulfonamide
CAS 389126-19-6C22H21N3O3S
4-[(4-Chlorophenyl)sulfonylamino]-N-[(3-hydroxyphenyl)methylideneamino]benzamide chemical structure, C20H16ClN3O4S, CAS 477732-69-7
4-[(4-Chlorophenyl)sulfonylamino]-N-[(3-hydroxyphenyl)methylideneamino]benzamide
CAS 477732-69-7C20H16ClN3O4S
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-fluorophenyl)methylideneamino]benzamide chemical structure, C20H15ClFN3O3S, CAS 477732-89-1
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-fluorophenyl)methylideneamino]benzamide
CAS 477732-89-1C20H15ClFN3O3S
N-[(4-Chlorophenyl)methylideneamino]-4-[(4-chlorophenyl)sulfonylamino]benzamide chemical structure, C20H15Cl2N3O3S, CAS 477733-25-8
N-[(4-Chlorophenyl)methylideneamino]-4-[(4-chlorophenyl)sulfonylamino]benzamide
CAS 477733-25-8C20H15Cl2N3O3S
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-ethoxyphenyl)methylideneamino]benzamide chemical structure, C22H20ClN3O4S, CAS 477732-76-6
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-ethoxyphenyl)methylideneamino]benzamide
CAS 477732-76-6C22H20ClN3O4S
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-methoxyphenyl)methylideneamino]benzamide chemical structure, C21H18ClN3O4S, CAS 477732-16-4
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-methoxyphenyl)methylideneamino]benzamide
CAS 477732-16-4C21H18ClN3O4S
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-nitrophenyl)methylideneamino]benzamide chemical structure, C20H15ClN4O5S, CAS 477732-86-8
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-nitrophenyl)methylideneamino]benzamide
CAS 477732-86-8C20H15ClN4O5S
4-[(4-Chlorophenyl)sulfonylamino]-N-[(3-nitrophenyl)methylideneamino]benzamide chemical structure, C20H15ClN4O5S, CAS 477732-79-9
4-[(4-Chlorophenyl)sulfonylamino]-N-[(3-nitrophenyl)methylideneamino]benzamide
CAS 477732-79-9C20H15ClN4O5S
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-methylphenyl)methylideneamino]benzamide chemical structure, C21H18ClN3O3S, CAS 477732-85-7
4-[(4-Chlorophenyl)sulfonylamino]-N-[(4-methylphenyl)methylideneamino]benzamide
CAS 477732-85-7C21H18ClN3O3S
N-(4-((2-(5-BR-2-Meo-benzylidene)hydrazino)carbonyl)PH)-4-CL-benzenesulfonamide chemical structure, C21H17BrClN3O4S, CAS 477732-70-0
N-(4-((2-(5-BR-2-Meo-benzylidene)hydrazino)carbonyl)PH)-4-CL-benzenesulfonamide
CAS 477732-70-0C21H17BrClN3O4S
4-Chloro-N-[4-({(2E)-2-[2-(trifluoromethyl)benzylidene]hydrazino}carbonyl)phenyl]benzenesulfonamide chemical structure, C21H15ClF3N3O3S, CAS 477732-88-0
4-Chloro-N-[4-({(2E)-2-[2-(trifluoromethyl)benzylidene]hydrazino}carbonyl)phenyl]benzenesulfonamide
CAS 477732-88-0C21H15ClF3N3O3S
N-(4-((2-(2-Bromobenzylidene)hydrazino)carbonyl)PH)-4-chlorobenzenesulfonamide chemical structure, C20H15BrClN3O3S, CAS 477732-80-2
N-(4-((2-(2-Bromobenzylidene)hydrazino)carbonyl)PH)-4-chlorobenzenesulfonamide
CAS 477732-80-2C20H15BrClN3O3S
N-[4-({(2E)-2-[2-(allyloxy)benzylidene]hydrazino}carbonyl)phenyl]-4-chlorobenzenesulfonamide chemical structure, C23H20ClN3O4S, CAS 765905-70-2
N-[4-({(2E)-2-[2-(allyloxy)benzylidene]hydrazino}carbonyl)phenyl]-4-chlorobenzenesulfonamide
CAS 765905-70-2C23H20ClN3O4S
4-CL-N-(4-((2-(2,3-Dichlorobenzylidene)hydrazino)carbonyl)PH)benzenesulfonamide chemical structure, C20H14Cl3N3O3S, CAS 765902-07-6
4-CL-N-(4-((2-(2,3-Dichlorobenzylidene)hydrazino)carbonyl)PH)benzenesulfonamide
CAS 765902-07-6C20H14Cl3N3O3S
N-(4-((2-(3-(Allyloxy)benzylidene)hydrazino)carbonyl)PH)-4-CL-benzenesulfonamide chemical structure, C23H20ClN3O4S, CAS 765313-13-1
N-(4-((2-(3-(Allyloxy)benzylidene)hydrazino)carbonyl)PH)-4-CL-benzenesulfonamide
CAS 765313-13-1C23H20ClN3O4S
4-CL-N-(4-((2-(2,6-Dichlorobenzylidene)hydrazino)carbonyl)PH)benzenesulfonamide chemical structure, C20H14Cl3N3O3S, CAS 765311-50-0
4-CL-N-(4-((2-(2,6-Dichlorobenzylidene)hydrazino)carbonyl)PH)benzenesulfonamide
CAS 765311-50-0C20H14Cl3N3O3S
4-Chloro-N-(4-((2-(2-chloro-5-nitrobenzylidene)hydrazino)carbonyl)phenyl)benzenesulfonamide chemical structure, C20H14Cl2N4O5S, CAS 882046-60-8
4-Chloro-N-(4-((2-(2-chloro-5-nitrobenzylidene)hydrazino)carbonyl)phenyl)benzenesulfonamide
CAS 882046-60-8C20H14Cl2N4O5S
4-Chloro-N-(4-((2-(4-(dimethylamino)benzylidene)hydrazino)carbonyl)phenyl)benzenesulfonamide chemical structure, C22H21ClN4O3S, CAS 882046-67-5
4-Chloro-N-(4-((2-(4-(dimethylamino)benzylidene)hydrazino)carbonyl)phenyl)benzenesulfonamide
CAS 882046-67-5C22H21ClN4O3S
4-Chloro-N-(4-(2-(2,3-dimethoxybenzylidene)hydrazinecarbonyl)phenyl)benzenesulfonamide chemical structure, C22H20ClN3O5S, CAS 881659-78-5
4-Chloro-N-(4-(2-(2,3-dimethoxybenzylidene)hydrazinecarbonyl)phenyl)benzenesulfonamide
CAS 881659-78-5C22H20ClN3O5S
4-CL-N-(4-((2-(2,4-Dihydroxybenzylidene)hydrazino)carbonyl)PH)benzenesulfonamide chemical structure, C20H16ClN3O5S, CAS 477732-13-1
4-CL-N-(4-((2-(2,4-Dihydroxybenzylidene)hydrazino)carbonyl)PH)benzenesulfonamide
CAS 477732-13-1C20H16ClN3O5S
4-Chloro-N-(4-{[(2E)-2-(2-hydroxy-5-methoxybenzylidene)hydrazino]carbonyl}phenyl)benzenesulfonamide chemical structure, C21H18ClN3O5S, CAS 477733-09-8
4-Chloro-N-(4-{[(2E)-2-(2-hydroxy-5-methoxybenzylidene)hydrazino]carbonyl}phenyl)benzenesulfonamide
CAS 477733-09-8C21H18ClN3O5S
4-Chloro-N-(4-((2-(2-hydroxybenzylidene)hydrazinyl)carbonyl)phenyl)benzenesulfonamide chemical structure, C20H16ClN3O4S, CAS 477733-63-4
4-Chloro-N-(4-((2-(2-hydroxybenzylidene)hydrazinyl)carbonyl)phenyl)benzenesulfonamide
CAS 477733-63-4C20H16ClN3O4S
N-(4-((2-(5-Bromo-2-hydroxybenzylidene)hydrazino)carbonyl)phenyl)-4-chlorobenzenesulfonamide chemical structure, C20H15BrClN3O4S, CAS 881453-81-2
N-(4-((2-(5-Bromo-2-hydroxybenzylidene)hydrazino)carbonyl)phenyl)-4-chlorobenzenesulfonamide
CAS 881453-81-2C20H15BrClN3O4S