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Murcko scaffold

Ring system with 3 rings and 26 atoms

183 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
183
With full pages
162
Scaffold SMILES

O=C(NN=Cc1ccc(OC(=O)c2ccccc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccc(OC(=O)c2ccccc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 183 chemicals

4-((2-(4-Methoxybenzoyl)hydrazinylidene)methyl)phenyl 3-bromobenzoate chemical structure, C22H17BrN2O4, CAS 303083-49-0
4-((2-(4-Methoxybenzoyl)hydrazinylidene)methyl)phenyl 3-bromobenzoate
CAS 303083-49-0C22H17BrN2O4
4-Hydroxybenzoic acid 2-((4-(benzoyloxy)-3-methoxyphenyl)methylene)hydrazide chemical structure, C22H18N2O5, CAS 303084-64-2
4-Hydroxybenzoic acid 2-((4-(benzoyloxy)-3-methoxyphenyl)methylene)hydrazide
CAS 303084-64-2C22H18N2O5
3,4-Dichlorobenzoic acid 2-[[3-ethoxy-4-[(4-propoxybenzoyl)oxy]phenyl]methylene]hydrazide chemical structure, C26H24Cl2N2O5, CAS 881464-18-2
3,4-Dichlorobenzoic acid 2-[[3-ethoxy-4-[(4-propoxybenzoyl)oxy]phenyl]methylene]hydrazide
CAS 881464-18-2C26H24Cl2N2O5
[4-[[(4-Nitrobenzoyl)hydrazinylidene]methyl]phenyl] 4-bromobenzoate chemical structure, C21H14BrN3O5, CAS 6646-59-9
[4-[[(4-Nitrobenzoyl)hydrazinylidene]methyl]phenyl] 4-bromobenzoate
CAS 6646-59-9C21H14BrN3O5
4-[(E)-{2-[(3-Nitrophenyl)carbonyl]hydrazinylidene}methyl]phenyl 4-bromobenzoate chemical structure, C21H14BrN3O5, CAS 342788-86-7
4-[(E)-{2-[(3-Nitrophenyl)carbonyl]hydrazinylidene}methyl]phenyl 4-bromobenzoate
CAS 342788-86-7C21H14BrN3O5
4-(2-(3,4,5-Trimethoxybenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C24H21ClN2O6, CAS 303087-86-7
4-(2-(3,4,5-Trimethoxybenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 303087-86-7C24H21ClN2O6
4-(2-(3-Chlorobenzoyl)carbohydrazonoyl)-2-methoxyphenyl 4-methoxybenzoate chemical structure, C23H19ClN2O5, CAS 402769-14-6
4-(2-(3-Chlorobenzoyl)carbohydrazonoyl)-2-methoxyphenyl 4-methoxybenzoate
CAS 402769-14-6C23H19ClN2O5
2-Methoxy-4-(2-(4-methoxybenzoyl)carbohydrazonoyl)phenyl benzoate chemical structure, C23H20N2O5, CAS 303083-97-8
2-Methoxy-4-(2-(4-methoxybenzoyl)carbohydrazonoyl)phenyl benzoate
CAS 303083-97-8C23H20N2O5
4-(2-(3-Bromobenzoyl)carbohydrazonoyl)-2-ethoxyphenyl 4-methoxybenzoate chemical structure, C24H21BrN2O5, CAS 494759-42-1
4-(2-(3-Bromobenzoyl)carbohydrazonoyl)-2-ethoxyphenyl 4-methoxybenzoate
CAS 494759-42-1C24H21BrN2O5
2-Ethoxy-4-(2-{4-nitrobenzoyl}carbohydrazonoyl)phenyl 4-fluorobenzoate chemical structure, C23H18FN3O6, CAS 352204-89-8
2-Ethoxy-4-(2-{4-nitrobenzoyl}carbohydrazonoyl)phenyl 4-fluorobenzoate
CAS 352204-89-8C23H18FN3O6
(E)-4-((2-(2-Methylbenzoyl)hydrazono)methyl)phenyl benzoate chemical structure, C22H18N2O3, CAS 330673-68-2
(E)-4-((2-(2-Methylbenzoyl)hydrazono)methyl)phenyl benzoate
CAS 330673-68-2C22H18N2O3
4-(2-(4-Hydroxybenzoyl)carbohydrazonoyl)phenyl benzoate chemical structure, C21H16N2O4, CAS 303082-89-5
4-(2-(4-Hydroxybenzoyl)carbohydrazonoyl)phenyl benzoate
CAS 303082-89-5C21H16N2O4
Benzoic acid, 4-(acetylamino)-, ((4-(benzoyloxy)phenyl)methylene)hydrazide chemical structure, C23H19N3O4, CAS 55901-33-2
Benzoic acid, 4-(acetylamino)-, ((4-(benzoyloxy)phenyl)methylene)hydrazide
CAS 55901-33-2C23H19N3O4
Benzoic acid, 4-(acetylamino)-, ((4-((3-nitrobenzoyl)oxy)phenyl)methylene)hydrazide chemical structure, C23H18N4O6, CAS 55901-34-3
Benzoic acid, 4-(acetylamino)-, ((4-((3-nitrobenzoyl)oxy)phenyl)methylene)hydrazide
CAS 55901-34-3C23H18N4O6
Benzoic acid, 4-(acetylamino)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)phenyl ester chemical structure, C25H22N4O5, CAS 55901-35-4
Benzoic acid, 4-(acetylamino)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)phenyl ester
CAS 55901-35-4C25H22N4O5
Benzoic acid, 2-(acetyloxy)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)phenyl ester chemical structure, C25H21N3O6, CAS 55901-36-5
Benzoic acid, 2-(acetyloxy)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)phenyl ester
CAS 55901-36-5C25H21N3O6
Benzoic acid, 4-(acetylamino)-, ((4-(benzoyloxy)-3-methoxyphenyl)methylene)hydrazide chemical structure, C24H21N3O5, CAS 55901-37-6
Benzoic acid, 4-(acetylamino)-, ((4-(benzoyloxy)-3-methoxyphenyl)methylene)hydrazide
CAS 55901-37-6C24H21N3O5
Benzoic acid, 4-(acetylamino)-, ((3-methoxy-4-((3-nitrobenzoyl)oxy)phenyl)methylene)hydrazide chemical structure, C24H20N4O7, CAS 55901-38-7
Benzoic acid, 4-(acetylamino)-, ((3-methoxy-4-((3-nitrobenzoyl)oxy)phenyl)methylene)hydrazide
CAS 55901-38-7C24H20N4O7
Benzoic acid, 2-(acetyloxy)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)-2-methoxyphenyl ester chemical structure, C26H23N3O7, CAS 55901-40-1
Benzoic acid, 2-(acetyloxy)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)-2-methoxyphenyl ester
CAS 55901-40-1C26H23N3O7
Benzoic acid, 4-(acetylamino)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)-2-methoxyphenyl, ester chemical structure, C26H24N4O6, CAS 56077-39-5
Benzoic acid, 4-(acetylamino)-, 4-(((4-(acetylamino)benzoyl)hydrazono)methyl)-2-methoxyphenyl, ester
CAS 56077-39-5C26H24N4O6
4-(2-(4-Chlorobenzoyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C21H14BrClN2O3, CAS 330971-95-4
4-(2-(4-Chlorobenzoyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 330971-95-4C21H14BrClN2O3
4-(2-(2,4-Dihydroxybenzoyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C21H14Cl2N2O5, CAS 764657-01-4
4-(2-(2,4-Dihydroxybenzoyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 764657-01-4C21H14Cl2N2O5
2-Ethoxy-4-(2-(4-nitrobenzoyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C23H17Cl2N3O6, CAS 357300-74-4
2-Ethoxy-4-(2-(4-nitrobenzoyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 357300-74-4C23H17Cl2N3O6
4-{(E)-[2-(3,4-Dichlorobenzoyl)hydrazono]methyl}phenyl 3,4-dimethoxybenzoate chemical structure, C23H18Cl2N2O5, CAS 478376-43-1
4-{(E)-[2-(3,4-Dichlorobenzoyl)hydrazono]methyl}phenyl 3,4-dimethoxybenzoate
CAS 478376-43-1C23H18Cl2N2O5