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Murcko scaffold

2-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide scaffold

64 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
64
With full pages
9
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide page
Murcko scaffold O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 64 chemicals

2-(2,4-Dichlorophenoxy)-N-(4-{[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)acetamide chemical structure, C20H18Cl2N4O4S, CAS 128720-92-3
2-(2,4-Dichlorophenoxy)-N-(4-{[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)acetamide
CAS 128720-92-3C20H18Cl2N4O4S
N-[4-(4,6-Dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-2-p-tolyloxy-acetamide chemical structure, C21H22N4O4S, CAS 315675-96-8
N-[4-(4,6-Dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-2-p-tolyloxy-acetamide
CAS 315675-96-8C21H22N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(3-methylphenoxy)acetamide chemical structure, C21H22N4O4S, CAS 328024-36-8
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(3-methylphenoxy)acetamide
CAS 328024-36-8C21H22N4O4S
2-(2,5-Dimethylphenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide chemical structure, C22H24N4O4S, CAS 443644-74-4
2-(2,5-Dimethylphenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide
CAS 443644-74-4C22H24N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(4-ethylphenoxy)acetamide chemical structure, C22H24N4O4S, CAS 501107-03-5
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(4-ethylphenoxy)acetamide
CAS 501107-03-5C22H24N4O4S
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-2-(2-isopropylphenoxy)acetamide chemical structure, C23H26N4O4S, CAS 606923-48-2
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-2-(2-isopropylphenoxy)acetamide
CAS 606923-48-2C23H26N4O4S
2-(2,6-Dimethylphenoxy)-N-(4-{[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)acetamide chemical structure, C22H24N4O4S, CAS 651017-94-6
2-(2,6-Dimethylphenoxy)-N-(4-{[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)acetamide
CAS 651017-94-6C22H24N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(4-methoxyphenoxy)acetamide chemical structure, C21H22N4O5S, CAS 438031-68-6
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(4-methoxyphenoxy)acetamide
CAS 438031-68-6C21H22N4O5S
2-(4-Chlorophenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide chemical structure, C20H19ClN4O4S, CAS 154820-80-1
2-(4-Chlorophenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide
CAS 154820-80-1C20H19ClN4O4S
2-(3-Methyl-4-propan-2-ylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C22H24N4O4S, CAS 384356-68-7
2-(3-Methyl-4-propan-2-ylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 384356-68-7C22H24N4O4S
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-2-m-tolyloxy-acetamide chemical structure, C19H18N4O4S, CAS 307540-44-9
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-2-m-tolyloxy-acetamide
CAS 307540-44-9C19H18N4O4S
2-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H16N4O4S, CAS 312526-31-1
2-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 312526-31-1C18H16N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-phenoxyacetamide chemical structure, C20H20N4O4S, CAS 312743-82-1
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-phenoxyacetamide
CAS 312743-82-1C20H20N4O4S
N-(4-(N-(4,6-Dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-2-(o-tolyloxy)acetamide chemical structure, C21H22N4O4S, CAS 328027-12-9
N-(4-(N-(4,6-Dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-2-(o-tolyloxy)acetamide
CAS 328027-12-9C21H22N4O4S
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-2-phenoxyacetamide chemical structure, C19H18N4O4S, CAS 303035-29-2
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-2-phenoxyacetamide
CAS 303035-29-2C19H18N4O4S
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-2-o-tolyloxy-acetamide chemical structure, C19H18N4O4S, CAS 452353-69-4
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-2-o-tolyloxy-acetamide
CAS 452353-69-4C19H18N4O4S
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-2-p-tolyloxy-acetamide chemical structure, C19H18N4O4S, CAS 452350-49-1
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-2-p-tolyloxy-acetamide
CAS 452350-49-1C19H18N4O4S
2-(2-Methoxy-phenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)-phenyl]-acetamide chemical structure, C19H18N4O5S, CAS 452353-81-0
2-(2-Methoxy-phenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)-phenyl]-acetamide
CAS 452353-81-0C19H18N4O5S
2-(2-Chlorophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H15ClN4O4S, CAS 452353-65-0
2-(2-Chlorophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 452353-65-0C18H15ClN4O4S
2-(2-Chlorophenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide chemical structure, C20H19ClN4O4S, CAS 442567-01-3
2-(2-Chlorophenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide
CAS 442567-01-3C20H19ClN4O4S
2-(4-Chlorophenoxy)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide chemical structure, C19H17ClN4O4S, CAS 294894-32-9
2-(4-Chlorophenoxy)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide
CAS 294894-32-9C19H17ClN4O4S
2-(4-Bromophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H15BrN4O4S, CAS 452353-59-2
2-(4-Bromophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 452353-59-2C18H15BrN4O4S
2-(4-Methoxyphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C19H18N4O5S, CAS 370852-15-6
2-(4-Methoxyphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 370852-15-6C19H18N4O5S
2-(2-Isopropyl-5-methylphenoxy)-N-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}acetamide chemical structure, C22H24N4O4S, CAS 383892-79-3
2-(2-Isopropyl-5-methylphenoxy)-N-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}acetamide
CAS 383892-79-3C22H24N4O4S