Murcko scaffold
Hexahydro-2H-furo(2,3-c)pyrrole scaffold
143 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 143
- With full pages
- 10
Scaffold SMILES
C1CC2CNCC2O1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 143 chemicals
![rac-tert-Butyl N-{[(3aR,6aR)-hexahydro-2H-furo[2,3-c]pyrrol-6a-yl]methyl}carbamate chemical structure, C12H22N2O3, CAS 209340-13-6](/s/LINBVMCMBXUMSN-BXKDBHETSA-N.svg)
rac-tert-Butyl N-{[(3aR,6aR)-hexahydro-2H-furo[2,3-c]pyrrol-6a-yl]methyl}carbamate
CAS 209340-13-6C12H22N2O3
![N-Boc-1-[(3aS,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-3a-yl]methanamine chemical structure, C12H22N2O3, CAS 250275-11-7](/s/NJJBVQRYYHYRHY-UHFFFAOYSA-N.svg)
N-Boc-1-[(3aS,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-3a-yl]methanamine
CAS 250275-11-7C12H22N2O3
![(Hexahydro-2H-furo[2,3-c]pyrrol-3a-yl)methanamine chemical structure, C7H14N2O, CAS 155448-68-3](/s/DQBKUAAAAMUTKQ-UHFFFAOYSA-N.svg)
(Hexahydro-2H-furo[2,3-c]pyrrol-3a-yl)methanamine
CAS 155448-68-3C7H14N2O
![N-((Hexahydro-2H-furo[2,3-c]pyrrol-6a-yl)methyl)acetamide chemical structure, C9H16N2O2, CAS 155448-57-0](/s/HLHZODAKWHYGTF-UHFFFAOYSA-N.svg)
N-((Hexahydro-2H-furo[2,3-c]pyrrol-6a-yl)methyl)acetamide
CAS 155448-57-0C9H16N2O2
![cis-tert-Butyl 2-(aminomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate chemical structure, C12H22N2O3, CAS 1241675-74-0](/s/VKZFHDQGLQGCGB-FIBVVXLUSA-N.svg)
cis-tert-Butyl 2-(aminomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate
CAS 1241675-74-0C12H22N2O3
![(2R,3AR,6aR)-tert-butyl 2-(aminomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate chemical structure, C12H22N2O3, CAS 1932511-57-3](/s/VKZFHDQGLQGCGB-BBBLOLIVSA-N.svg)
(2R,3AR,6aR)-tert-butyl 2-(aminomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate
CAS 1932511-57-3C12H22N2O3
![2-Aminomethyl-hexahydro-furo[2,3-c]pyrrole-5-carboxylic acid tert-butyl ester chemical structure, C12H22N2O3, CAS 1314787-15-9](/s/VKZFHDQGLQGCGB-UHFFFAOYSA-N.svg)
2-Aminomethyl-hexahydro-furo[2,3-c]pyrrole-5-carboxylic acid tert-butyl ester
CAS 1314787-15-9C12H22N2O3
Hexahydro-2H-furo(2,3-c)pyrrole
CAS 1214875-23-6C6H11NO
![rac-[(3aR,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-6a-yl]methanamine chemical structure, C7H14N2O, CAS 1932279-33-8](/s/CCYKKVGTHIOPTJ-RQJHMYQMSA-N.svg)
rac-[(3aR,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-6a-yl]methanamine
CAS 1932279-33-8C7H14N2O
![rac-(3aR,6aR)-hexahydro-2H-furo[2,3-c]pyrrole hydrochloride chemical structure, C6H12ClNO, CAS 1361220-22-5](/s/QMLYGZYYFLBLBI-IBTYICNHSA-N.svg)
rac-(3aR,6aR)-hexahydro-2H-furo[2,3-c]pyrrole hydrochloride
CAS 1361220-22-5C6H12ClNO
![(3aR,6aR)-Hexahydro-2H-furo[2,3-c]pyrrole chemical structure, C6H11NO, CAS 1609384-28-2](/s/KUQSQOIIMSDGFF-RITPCOANSA-N.svg)
(3aR,6aR)-Hexahydro-2H-furo[2,3-c]pyrrole
CAS 1609384-28-2C6H11NO
![Hexahydro-2H-furo[2,3-c]pyrrole hydrochloride chemical structure, C6H12ClNO, CAS 1955531-55-1](/s/QMLYGZYYFLBLBI-UHFFFAOYSA-N.svg)
Hexahydro-2H-furo[2,3-c]pyrrole hydrochloride
CAS 1955531-55-1C6H12ClNO
![tert-Butyl (hexahydro-2H-furo[2,3-c]pyrrol-3-yl)carbamate chemical structure, C11H20N2O3, CAS 479090-77-2](/s/DXQODYVKRDPTKR-UHFFFAOYSA-N.svg)
tert-Butyl (hexahydro-2H-furo[2,3-c]pyrrol-3-yl)carbamate
CAS 479090-77-2C11H20N2O3
rac-(2R,3aR,6aR)-5-((tert-butoxy)carbonyl)-hexahydro-2H-furo(2,3-c)pyrrole-2-carboxylic acid
CAS 1391733-09-7C12H19NO5
![cis-Hexahydro-2H-furo[2,3-c]pyrrole hydrochloride chemical structure, C6H12ClNO, CAS 1820583-24-1](/s/QMLYGZYYFLBLBI-RIHPBJNCSA-N.svg)
cis-Hexahydro-2H-furo[2,3-c]pyrrole hydrochloride
CAS 1820583-24-1C6H12ClNO
rac-(3aR,6aR)-hexahydro-2H-furo(2,3-c)pyrrole
CAS 1361295-05-7C6H11NO
![Hexahydro-2H-furo[2,3-c]pyrrole-3a-carboxylic acid chemical structure, C7H11NO3, CAS 1511449-47-0](/s/LKIDEIDZBYIDNU-UHFFFAOYSA-N.svg)
Hexahydro-2H-furo[2,3-c]pyrrole-3a-carboxylic acid
CAS 1511449-47-0C7H11NO3
![Methyl hexahydro-2H-furo[2,3-c]pyrrole-3a-carboxylate chemical structure, C8H13NO3, CAS 1782902-51-5](/s/AXQXLXSIFGUDBL-UHFFFAOYSA-N.svg)
Methyl hexahydro-2H-furo[2,3-c]pyrrole-3a-carboxylate
CAS 1782902-51-5C8H13NO3
![trans-Hexahydro-furo[2,3-c]pyrrole chemical structure, C6H11NO, CAS 2748400-48-6](/s/KUQSQOIIMSDGFF-WDSKDSINSA-N.svg)
trans-Hexahydro-furo[2,3-c]pyrrole
CAS 2748400-48-6C6H11NO
![(3AR,6aS)-hexahydro-2H-furo[2,3-c]pyrrole chemical structure, C6H11NO, CAS 2382634-94-6](/s/KUQSQOIIMSDGFF-PHDIDXHHSA-N.svg)
(3AR,6aS)-hexahydro-2H-furo[2,3-c]pyrrole
CAS 2382634-94-6C6H11NO
![tert-Butyl (2R,3aS,6aS)-2-(aminomethyl)-2,3,3a,4,6,6a-hexahydrofuro[2,3-c]pyrrole-5-carboxylate chemical structure, C12H22N2O3, CAS 1932373-59-5](/s/VKZFHDQGLQGCGB-IVZWLZJFSA-N.svg)
tert-Butyl (2R,3aS,6aS)-2-(aminomethyl)-2,3,3a,4,6,6a-hexahydrofuro[2,3-c]pyrrole-5-carboxylate
CAS 1932373-59-5C12H22N2O3
![tert-Butyl (2S,3aS,6aS)-2-(aminomethyl)-2,3,3a,4,6,6a-hexahydrofuro[2,3-c]pyrrole-5-carboxylate chemical structure, C12H22N2O3, CAS 1932295-69-6](/s/VKZFHDQGLQGCGB-LPEHRKFASA-N.svg)
tert-Butyl (2S,3aS,6aS)-2-(aminomethyl)-2,3,3a,4,6,6a-hexahydrofuro[2,3-c]pyrrole-5-carboxylate
CAS 1932295-69-6C12H22N2O3
![cis-tert-Butyl 2-(iodomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate chemical structure, C12H20INO3, CAS 1445949-63-2](/s/SVZZQMWNBGDULD-FIBVVXLUSA-N.svg)
cis-tert-Butyl 2-(iodomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate
CAS 1445949-63-2C12H20INO3
![Racemic-(3R,3aS,6aS)-tert-butyl 3-(aminomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate chemical structure, C12H22N2O3, CAS 1273568-20-9](/s/SCNZIMGXJYWNJL-OPRDCNLKSA-N.svg)
Racemic-(3R,3aS,6aS)-tert-butyl 3-(aminomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate
CAS 1273568-20-9C12H22N2O3
- rac-tert-Butyl(3R,3aS,6aR)-3-amino-hexahydro-2H-furo[2,3-c]pyrrole-5-carboxylate2375249-03-7C11H20N2O3
- tert-Butyl rel-(3R,3aR,6aR)-3-aminohexahydro-5H-furo[2,3-c]pyrrole-5-carboxylate2177267-07-9C11H20N2O3
- rac-tert-Butyl (3R,3aS,6aS)-3-(hydroxymethyl)-hexahydro-2H-furo[2,3-c]pyrrole-5-carboxylate2380901-66-4C12H21NO4
- Racemic-(3S,3aS,6aS)-tert-butyl 3-(hydroxymethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate1273563-99-7C12H21NO4
- Rel-((2S,3aS,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-2-yl)methanol2095192-23-5C7H13NO2
- Racemic-(3R,3aS,6aS)-tert-butyl3-(aminomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate2380893-89-8C12H22N2O3
- Rel-((2R,3aS,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-2-yl)methanol2095192-12-2C7H13NO2
- Racemic-(3S,3aS,6aS)-5-(t-butoxycarbonyl)hexahydro-2H-furo[2,3-c]pyrrole-3-carboxylic acid2287237-25-4C12H19NO5
- (3S,3aR,6aR)-5-[(tert-Butoxy)carbonyl]-hexahydro-2H-furo[2,3-c]pyrrole-3-carboxylic acid2382059-98-3C12H19NO5
- Rac-5-tert-butyl 3-methyl (3S,3AS,6AS)-hexahydro-5H-furo[2,3-C]pyrrole-3,5-dicarboxylate1445950-97-9C13H21NO5
- 2-((2S,3aS,6aS)-5-(tert-Butoxycarbonyl)hexahydro-2H-furo[2,3-c]pyrrol-2-yl)acetic acid1445951-31-4C13H21NO5
- rel-(3aR,6aS)-3,3-difluoro-2,3a,4,5,6,6a-hexahydrofuro[2,3-c]pyrrole2177258-45-4C6H9F2NO
- (3aR,6aR)-3,3-Difluoro-2,3a,4,5,6,6a-hexahydrofuro[2,3-c]pyrrole1932254-28-8C6H9F2NO
- (3aS,6aR)-3,3-Difluoro-2,3a,4,5,6,6a-hexahydrofuro[2,3-c]pyrrole2381445-48-1C6H9F2NO
- Racemic-(2S,3aS,6aS)-tert-butyl 2-(iodomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate1445951-05-2C12H20INO3
- Racemic-2-((2R,3aS,6aS)-5-(tert-butoxycarbonyl)hexahydro-2H-furo[2,3-c]pyrrol-2-yl)acetic acid1445951-51-8C13H21NO5
- 5H-Furo[2,3-c]pyrrole-3,5-dicarboxylic acid, hexahydro-, 5-(1,1-dimethylethyl) 3-ethyl ester, (3R,3aR,6aR)-rel-1445951-12-1C14H23NO5
- rac-(3aR,6aR)-5-((tert-butoxy)carbonyl)-hexahydro-2H-furo(2,3-c)pyrrole-6a-carboxylic acid2307780-28-3C12H19NO5
- 5-(tert-Butoxycarbonyl)hexahydro-6aH-furo[2,3-c]pyrrole-6a-carboxylic acid2060046-95-7C12H19NO5
- rac-(2S,3AS,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-2-ylmethanol hydrochloride2095192-24-6C7H14ClNO2
- rac-(2R,3AS,6aS)-hexahydro-2H-furo[2,3-c]pyrrol-2-ylmethanol hydrochloride2095192-13-3C7H14ClNO2
- 2-((3R,3AS,6AS)-5-(tert-butoxycarbonyl)hexahydro-2H-furo[2,3-C]pyrrol-3-yl)acetic acid1273566-61-2C13H21NO5
- Racemic-(3R,3aS,6aS)-5-(tert-butoxycarbonyl)hexahydro-2H-furo[2,3-c]pyrrole-3-carboxylic acid1273566-11-2C12H19NO5
- Racemic-(3R,3aS,6aS)-tert-butyl 3-(hydroxymethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate1273576-62-7C12H21NO4
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