Murcko scaffold
Ring system with 4 rings and 25 atoms
565 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 565
- With full pages
- 14
Scaffold SMILES
O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 529 to 565 of 565 chemicals
![rac-2-({[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}methyl)butanoic acid chemical structure, C28H34N2O5, CAS 2228017-93-2](/s/JCNWTRRCFQIVFD-YPJRHXLCSA-N.svg)
rac-2-({[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}methyl)butanoic acid
CAS 2228017-93-2C28H34N2O5
![(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2227700-29-8](/s/CPEPSQONHPPGJE-XHNVNVPESA-N.svg)
(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methylbutanoic acid
CAS 2227700-29-8C28H34N2O5
![rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2227973-97-7](/s/JHHGEXMAZUCXRJ-YPJRHXLCSA-N.svg)
rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbutanoic acid
CAS 2227973-97-7C28H34N2O5
![rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-hydroxypropanoic acid chemical structure, C26H30N2O6, CAS 2228017-96-5](/s/NYAZUANVNGKTCL-UYHNVOLQSA-N.svg)
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-hydroxypropanoic acid
CAS 2228017-96-5C26H30N2O6
![rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-(prop-2-yn-1-yl)formamido}acetic acid chemical structure, C28H30N2O5, CAS 2227845-96-5](/s/IOGQBQDQCNJWHA-PMACEKPBSA-N.svg)
rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-(prop-2-yn-1-yl)formamido}acetic acid
CAS 2227845-96-5C28H30N2O5
![rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pent-4-ynoic acid chemical structure, C28H30N2O5, CAS 2227923-46-6](/s/DAIRFQYYADZTQK-NHDFCTKWSA-N.svg)
rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pent-4-ynoic acid
CAS 2227923-46-6C28H30N2O5
![rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}acetic acid chemical structure, C25H28N2O5, CAS 2227650-27-1](/s/YFULZHIYSZQFOV-IRXDYDNUSA-N.svg)
rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}acetic acid
CAS 2227650-27-1C25H28N2O5
![rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbut-2-enoic acid chemical structure, C28H32N2O5, CAS 2227808-31-1](/s/ADPBACJJRTVVSQ-CWJMTQFSSA-N.svg)
rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbut-2-enoic acid
CAS 2227808-31-1C28H32N2O5
![rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2648934-59-0](/s/FRCGIUIACNVAAB-OQYLILOHSA-N.svg)
rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbutanoic acid
CAS 2648934-59-0C28H34N2O5
![rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2,2-dimethylpropanoic acid chemical structure, C28H34N2O5, CAS 2227808-34-4](/s/XIWPUVKQECFJOS-OALUTQOASA-N.svg)
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2,2-dimethylpropanoic acid
CAS 2227808-34-4C28H34N2O5
![rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2227974-08-3](/s/KXFADALUYLMMFC-GUMHCPJTSA-N.svg)
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylbutanoic acid
CAS 2227974-08-3C28H34N2O5
![(2S)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxypropanoic acid chemical structure, C26H30N2O6, CAS 2227756-35-4](/s/UCXKIMHBJOXPCY-QQMNAOGKSA-N.svg)
(2S)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxypropanoic acid
CAS 2227756-35-4C26H30N2O6
![rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}but-2-ynoic acid chemical structure, C27H28N2O5, CAS 2227758-88-3](/s/PGMHGOBZCCGONP-OALUTQOASA-N.svg)
rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}but-2-ynoic acid
CAS 2227758-88-3C27H28N2O5
![(3R)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}butanoic acid chemical structure, C27H32N2O5, CAS 2227785-99-9](/s/QOLCKHUCGZFNNY-QYZOEREBSA-N.svg)
(3R)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}butanoic acid
CAS 2227785-99-9C27H32N2O5
![rac-4-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}butanoic acid chemical structure, C28H34N2O5, CAS 2227701-24-6](/s/JJGYHQCIUJFWDI-PMACEKPBSA-N.svg)
rac-4-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}butanoic acid
CAS 2227701-24-6C28H34N2O5
![rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}-2-methylpropanoic acid chemical structure, C28H34N2O5, CAS 2227845-86-3](/s/NTDMTBAHMNJSEQ-OALUTQOASA-N.svg)
rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}-2-methylpropanoic acid
CAS 2227845-86-3C28H34N2O5
![(3S)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid chemical structure, C28H34N2O5, CAS 2227792-24-5](/s/AVJZDOPUCYRIJX-UFYCRDLUSA-N.svg)
(3S)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid
CAS 2227792-24-5C28H34N2O5
![(3R)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid chemical structure, C28H34N2O5, CAS 2227860-63-9](/s/AVJZDOPUCYRIJX-ZCNNSNEGSA-N.svg)
(3R)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid
CAS 2227860-63-9C28H34N2O5
![(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}butanoic acid chemical structure, C27H32N2O5, CAS 2227852-60-8](/s/NOHIAXJUNUZHIU-LLJLJFOGSA-N.svg)
(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}butanoic acid
CAS 2227852-60-8C27H32N2O5
![rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxybutanoic acid chemical structure, C27H32N2O6, CAS 2227948-69-6](/s/SKTDRBGPZMUMJB-JVUMBYKBSA-N.svg)
rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxybutanoic acid
CAS 2227948-69-6C27H32N2O6
![(2S,3R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxybutanoic acid chemical structure, C27H32N2O6, CAS 2227899-28-5](/s/JTSPRFBIGFAUCP-REYXVDKWSA-N.svg)
(2S,3R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxybutanoic acid
CAS 2227899-28-5C27H32N2O6
![rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-(prop-2-en-1-yl)formamido}acetic acid chemical structure, C28H32N2O5, CAS 2227724-95-8](/s/GHFVPQHIZKJDOZ-PMACEKPBSA-N.svg)
rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-(prop-2-en-1-yl)formamido}acetic acid
CAS 2227724-95-8C28H32N2O5
![(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid chemical structure, C28H34N2O5, CAS 2227782-02-5](/s/XYIZNOCUUULHMI-XHNVNVPESA-N.svg)
(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid
CAS 2227782-02-5C28H34N2O5
![rac-2-{N-ethyl-1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}acetic acid chemical structure, C27H32N2O5, CAS 2227873-05-2](/s/KARLXMSOSFSEPA-OALUTQOASA-N.svg)
rac-2-{N-ethyl-1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}acetic acid
CAS 2227873-05-2C27H32N2O5
- rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}acetic acid2227896-31-1C26H30N2O5
- (2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-4-hydroxybutanoic acid2227725-32-6C27H32N2O6
- rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methylpropanoic acid2227785-26-2C27H32N2O5
- rac-2-{1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}butanoic acid2227921-94-8C28H34N2O5
- rac-5-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid2227671-86-3C28H34N2O5
- (2S)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-hydroxypropanoic acid2227671-94-3C26H30N2O6
- rac-2-[(2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}ethyl)sulfanyl]acetic acid2227750-22-1C27H32N2O5S
- rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2,2-difluoropropanoic acid2227649-93-4C26H28F2N2O5
- (3S)-3-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}butanoic acid2227703-18-4C27H32N2O5
- rac-2-({1-[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}oxy)acetic acid2227793-35-1C26H30N2O6
- rac-4-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methylbutanoic acid2228020-67-3C28H34N2O5
- rac-2-({[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}oxy)acetic acid2227846-66-2C25H28N2O6
- 4-[(9H-Fluoren-9-ylmethoxycarbonylamino)methyl]-1-methylcyclohexane-1-carboxylic acid3022955-61-6C24H27NO4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCc1ccccc1)OCC1c2ccccc2-c2ccccc21109 chemicals
O=S(=O)(NCCCn1c2ccccc2c2ccccc21)c1ccccc16 chemicals
O=C(NCc1ccccn1)OCC1c2ccccc2-c2ccccc216 chemicals
O=C(NCc1cccnc1)OCC1c2ccccc2-c2ccccc215 chemicals
O=C(NCC1CCOCC1)OCC1c2ccccc2-c2ccccc215 chemicals
c1ccc(CNCCCn2c3ccccc3c3ccccc32)cc12 chemicals
O=C(COc1ccccc1)NN=C1c2ccccc2-c2ccccc212 chemicals
O=C(NCC1CCNCC1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(NCC1CCCOC1)OCC1c2ccccc2-c2ccccc211 chemical
c1ccc(CNCCCn2c3c(c4ccccc42)CCCC3)cc11 chemical
O=C(NCC1CCCCN1)OCC1c2ccccc2-c2ccccc211 chemical
C(#CC1c2ccccc2-c2ccccc21)CNCc1ccccc11 chemical