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Murcko scaffold

Ring system with 4 rings and 25 atoms

565 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
565
With full pages
14
Scaffold SMILES

O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 481 to 528 of 565 chemicals

(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-3,3-dimethylcyclohexyl)methyl]-N-methylcarbamate chemical structure, C25H31NO3, CAS 2770495-09-3
(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-3,3-dimethylcyclohexyl)methyl]-N-methylcarbamate
CAS 2770495-09-3C25H31NO3
(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-4-methylcyclohexyl)methyl]-N-methylcarbamate chemical structure, C24H29NO3, CAS 2770501-16-9
(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-4-methylcyclohexyl)methyl]-N-methylcarbamate
CAS 2770501-16-9C24H29NO3
(9H-Fluoren-9-yl)methyl N-[(1-hydroxycyclohexyl)methyl]-N-methylcarbamate chemical structure, C23H27NO3, CAS 2770555-82-1
(9H-Fluoren-9-yl)methyl N-[(1-hydroxycyclohexyl)methyl]-N-methylcarbamate
CAS 2770555-82-1C23H27NO3
(9H-Fluoren-9-yl)methyl N-[(4,4-difluoro-1-hydroxycyclohexyl)methyl]-N-methylcarbamate chemical structure, C23H25F2NO3, CAS 2770495-15-1
(9H-Fluoren-9-yl)methyl N-[(4,4-difluoro-1-hydroxycyclohexyl)methyl]-N-methylcarbamate
CAS 2770495-15-1C23H25F2NO3
(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-3,5-dimethylcyclohexyl)methyl]carbamate chemical structure, C24H29NO3, CAS 2770499-35-7
(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-3,5-dimethylcyclohexyl)methyl]carbamate
CAS 2770499-35-7C24H29NO3
(9H-Fluoren-9-yl)methyl N-{[(1r,4r)-4-ethynylcyclohexyl]methyl}carbamate chemical structure, C24H25NO2, CAS 2770452-23-6
(9H-Fluoren-9-yl)methyl N-{[(1r,4r)-4-ethynylcyclohexyl]methyl}carbamate
CAS 2770452-23-6C24H25NO2
(9H-Fluoren-9-yl)methyl N-(cyclohexylmethyl)-N-(prop-2-en-1-yl)carbamate chemical structure, C25H29NO2, CAS 2770529-17-2
(9H-Fluoren-9-yl)methyl N-(cyclohexylmethyl)-N-(prop-2-en-1-yl)carbamate
CAS 2770529-17-2C25H29NO2
2-(4,4-Difluorocyclohexyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)acetic acid chemical structure, C24H25F2NO4, CAS 2279733-96-7
2-(4,4-Difluorocyclohexyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)acetic acid
CAS 2279733-96-7C24H25F2NO4
2-(4,4-Dimethylcyclohexyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid chemical structure, C25H29NO4, CAS 1869510-63-3
2-(4,4-Dimethylcyclohexyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid
CAS 1869510-63-3C25H29NO4
(9H-Fluoren-9-yl)methyl ((1-(bromomethyl)cyclohexyl)methyl)carbamate chemical structure, C23H26BrNO2, CAS 3026690-41-2
(9H-Fluoren-9-yl)methyl ((1-(bromomethyl)cyclohexyl)methyl)carbamate
CAS 3026690-41-2C23H26BrNO2
(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-(1-methylcyclohexyl)acetic acid chemical structure, C24H27NO4, CAS 2349749-40-0
(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-(1-methylcyclohexyl)acetic acid
CAS 2349749-40-0C24H27NO4
1-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-4,4-difluorocyclohexane-1-carboxylic acid chemical structure, C23H23F2NO4, CAS 3017264-00-2
1-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-4,4-difluorocyclohexane-1-carboxylic acid
CAS 3017264-00-2C23H23F2NO4
2-(4,4-Difluorocyclohexyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C24H25F2NO4, CAS 2354418-70-3
2-(4,4-Difluorocyclohexyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 2354418-70-3C24H25F2NO4
(3R)-3-(4,4-Difluorocyclohexyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C24H25F2NO4, CAS 2276237-16-0
(3R)-3-(4,4-Difluorocyclohexyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 2276237-16-0C24H25F2NO4
(3S)-3-(4,4-Difluorocyclohexyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C24H25F2NO4, CAS 2272629-15-7
(3S)-3-(4,4-Difluorocyclohexyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 2272629-15-7C24H25F2NO4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4,4-dimethylcyclohexyl)acetic acid chemical structure, C25H29NO4, CAS 1312298-39-7
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4,4-dimethylcyclohexyl)acetic acid
CAS 1312298-39-7C25H29NO4
(2S)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2227705-55-5
(2S)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methylbutanoic acid
CAS 2227705-55-5C28H34N2O5
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2227663-59-2
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methylbutanoic acid
CAS 2227663-59-2C28H34N2O5
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid chemical structure, C28H34N2O5, CAS 2228015-48-1
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pentanoic acid
CAS 2228015-48-1C28H34N2O5
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methoxypropanoic acid chemical structure, C27H32N2O6, CAS 2228021-90-5
rac-3-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-2-methoxypropanoic acid
CAS 2228021-90-5C27H32N2O6
(2S)-2-{1-[(1RS,2SR)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}propanoic acid chemical structure, C27H32N2O5, CAS 2227756-82-1
(2S)-2-{1-[(1RS,2SR)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]-N-methylformamido}propanoic acid
CAS 2227756-82-1C27H32N2O5
(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxypropanoic acid chemical structure, C26H30N2O6, CAS 2227838-21-1
(2R)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-hydroxypropanoic acid
CAS 2227838-21-1C26H30N2O6
(2S)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methoxypropanoic acid chemical structure, C27H32N2O6, CAS 2227898-07-7
(2S)-2-{[(1RS,2SR)-2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}-3-methoxypropanoic acid
CAS 2227898-07-7C27H32N2O6
rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pent-4-enoic acid chemical structure, C28H32N2O5, CAS 2227935-32-0
rac-2-{[(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl]formamido}pent-4-enoic acid
CAS 2227935-32-0C28H32N2O5