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Murcko scaffold

Ring system with 4 rings and 25 atoms

565 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
565
With full pages
14
Scaffold SMILES

O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 565 chemicals

2-(1-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-(prop-2-yn-1-yl)formamido)acetic acid chemical structure, C28H30N2O5, CAS 2171256-85-0
2-(1-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-(prop-2-yn-1-yl)formamido)acetic acid
CAS 2171256-85-0C28H30N2O5
3-(N-Ethyl-1-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)propanoic acid chemical structure, C28H34N2O5, CAS 2172530-84-4
3-(N-Ethyl-1-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)propanoic acid
CAS 2172530-84-4C28H34N2O5
2-(1-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)-2-methylpropanoic acid chemical structure, C28H34N2O5, CAS 2172530-91-3
2-(1-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)-2-methylpropanoic acid
CAS 2172530-91-3C28H34N2O5
2-({4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pent-4-enoic acid chemical structure, C28H32N2O5, CAS 2171299-73-1
2-({4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pent-4-enoic acid
CAS 2171299-73-1C28H32N2O5
2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)-2-methylpropanoic acid chemical structure, C28H34N2O5, CAS 2172344-56-6
2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)-2-methylpropanoic acid
CAS 2172344-56-6C28H34N2O5
(2R)-2-({4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid chemical structure, C27H32N2O5, CAS 2171143-14-7
(2R)-2-({4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid
CAS 2171143-14-7C27H32N2O5
2-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)butanoic acid chemical structure, C28H34N2O5, CAS 2171767-65-8
2-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)butanoic acid
CAS 2171767-65-8C28H34N2O5
(2S)-2-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)butanoic acid chemical structure, C28H34N2O5, CAS 2171223-36-0
(2S)-2-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)butanoic acid
CAS 2171223-36-0C28H34N2O5
2-(1-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-(2-hydroxyethyl)formamido)acetic acid chemical structure, C27H32N2O6, CAS 2172170-08-8
2-(1-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-(2-hydroxyethyl)formamido)acetic acid
CAS 2172170-08-8C27H32N2O6
(3R)-3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)butanoic acid chemical structure, C28H34N2O5, CAS 2171252-88-1
(3R)-3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)butanoic acid
CAS 2171252-88-1C28H34N2O5
(2R)-2-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid chemical structure, C28H34N2O5, CAS 2171299-97-9
(2R)-2-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid
CAS 2171299-97-9C28H34N2O5
2-[({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)oxy]propanoic acid chemical structure, C26H30N2O6, CAS 2172020-89-0
2-[({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)oxy]propanoic acid
CAS 2172020-89-0C26H30N2O6
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)butanoic acid chemical structure, C28H34N2O5, CAS 2171723-02-5
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)butanoic acid
CAS 2171723-02-5C28H34N2O5
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2171922-45-3
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbutanoic acid
CAS 2171922-45-3C28H34N2O5
(2S)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid chemical structure, C28H34N2O5, CAS 2648937-45-3
(2S)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid
CAS 2648937-45-3C28H34N2O5
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methoxypropanoic acid chemical structure, C27H32N2O6, CAS 2171922-55-5
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methoxypropanoic acid
CAS 2171922-55-5C27H32N2O6
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid chemical structure, C27H32N2O5, CAS 2171804-45-6
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid
CAS 2171804-45-6C27H32N2O5
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2,2-difluoropropanoic acid chemical structure, C26H28F2N2O5, CAS 2171922-63-5
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2,2-difluoropropanoic acid
CAS 2171922-63-5C26H28F2N2O5
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid chemical structure, C26H30N2O6, CAS 2172218-84-5
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid
CAS 2172218-84-5C26H30N2O6
3-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)-2-methylpropanoic acid chemical structure, C28H34N2O5, CAS 2172219-67-7
3-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)-2-methylpropanoic acid
CAS 2172219-67-7C28H34N2O5
(3R)-3-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid chemical structure, C28H34N2O5, CAS 2171365-81-2
(3R)-3-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid
CAS 2171365-81-2C28H34N2O5
2-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]acetic acid chemical structure, C26H30N2O5, CAS 2172429-52-4
2-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]acetic acid
CAS 2172429-52-4C26H30N2O5
4-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)but-2-ynoic acid chemical structure, C28H30N2O5, CAS 2172290-98-9
4-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)but-2-ynoic acid
CAS 2172290-98-9C28H30N2O5
(2R)-2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)butanoic acid chemical structure, C28H34N2O5, CAS 2171151-13-4
(2R)-2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexyl}formamido)butanoic acid
CAS 2171151-13-4C28H34N2O5