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Murcko scaffold

Ring system with 4 rings and 25 atoms

565 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
565
With full pages
14
Scaffold SMILES

O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 565 chemicals

1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexane-1-carboxylic acid chemical structure, C24H27NO4, CAS 1550426-37-3
1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylcyclohexane-1-carboxylic acid
CAS 1550426-37-3C24H27NO4
rac-(9H-Fluoren-9-yl)methyl N-{[(1R,2R)-2-hydroxycyclohexyl]methyl}carbamate chemical structure, C22H25NO3, CAS 1821779-07-0
rac-(9H-Fluoren-9-yl)methyl N-{[(1R,2R)-2-hydroxycyclohexyl]methyl}carbamate
CAS 1821779-07-0C22H25NO3
(9H-Fluoren-9-yl)methyl N-(1-cyclohexyl-2-hydroxyethyl)carbamate chemical structure, C23H27NO3, CAS 1878075-43-4
(9H-Fluoren-9-yl)methyl N-(1-cyclohexyl-2-hydroxyethyl)carbamate
CAS 1878075-43-4C23H27NO3
(9H-Fluoren-9-yl)methyl N-[(1R)-1-cyclohexyl-2-hydroxyethyl]carbamate chemical structure, C23H27NO3, CAS 1139710-59-0
(9H-Fluoren-9-yl)methyl N-[(1R)-1-cyclohexyl-2-hydroxyethyl]carbamate
CAS 1139710-59-0C23H27NO3
(9H-Fluoren-9-yl)methyl N-[(1S)-1-cyclohexyl-2-hydroxyethyl]carbamate chemical structure, C23H27NO3, CAS 1139710-57-8
(9H-Fluoren-9-yl)methyl N-[(1S)-1-cyclohexyl-2-hydroxyethyl]carbamate
CAS 1139710-57-8C23H27NO3
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(1-methylcyclohexyl)acetic acid chemical structure, C24H27NO4, CAS 2003985-34-8
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(1-methylcyclohexyl)acetic acid
CAS 2003985-34-8C24H27NO4
N-Fmoc-N-(cyclohexylmethyl)-glycine chemical structure, C24H27NO4, CAS 1374785-49-5
N-Fmoc-N-(cyclohexylmethyl)-glycine
CAS 1374785-49-5C24H27NO4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-hydroxycyclohexyl)acetic acid chemical structure, C23H25NO5, CAS 2230804-09-6
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-hydroxycyclohexyl)acetic acid
CAS 2230804-09-6C23H25NO5
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4,4-difluorocyclohexyl)acetic acid chemical structure, C23H23F2NO4, CAS 2279457-71-3
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4,4-difluorocyclohexyl)acetic acid
CAS 2279457-71-3C23H23F2NO4
4-[(9H-Fluoren-9-ylmethoxycarbonylamino)methyl]-4-fluorocyclohexane-1-carboxylic acid chemical structure, C23H24FNO4, CAS 2375268-59-8
4-[(9H-Fluoren-9-ylmethoxycarbonylamino)methyl]-4-fluorocyclohexane-1-carboxylic acid
CAS 2375268-59-8C23H24FNO4
(2S)-2-(4,4-Difluorocyclohexyl)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetic acid chemical structure, C23H23F2NO4, CAS 2248184-59-8
(2S)-2-(4,4-Difluorocyclohexyl)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetic acid
CAS 2248184-59-8C23H23F2NO4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((1r,4S)-4-methylcyclohexyl)acetic acid chemical structure, C24H27NO4, CAS 1312298-38-6
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((1r,4S)-4-methylcyclohexyl)acetic acid
CAS 1312298-38-6C24H27NO4
1-{[(tert-Butoxy)carbonyl]amino}-4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexane-1-carboxylic acid chemical structure, C28H34N2O6, CAS 914358-29-5
1-{[(tert-Butoxy)carbonyl]amino}-4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexane-1-carboxylic acid
CAS 914358-29-5C28H34N2O6
(1RS,2SR,4RS&,5SR&)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4,5-dihydroxycyclohexane-1-carboxylic acid chemical structure, C23H25NO6, CAS 2445749-37-9
(1RS,2SR,4RS&,5SR&)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4,5-dihydroxycyclohexane-1-carboxylic acid
CAS 2445749-37-9C23H25NO6
(9H-Fluoren-9-yl)methyl N-{[(1s,4s)-4-aminocyclohexyl]methyl}carbamate chemical structure, C22H26N2O2, CAS 2137029-19-5
(9H-Fluoren-9-yl)methyl N-{[(1s,4s)-4-aminocyclohexyl]methyl}carbamate
CAS 2137029-19-5C22H26N2O2
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(1-methylcyclohexyl)acetic acid chemical structure, C24H27NO4, CAS 2350460-04-5
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(1-methylcyclohexyl)acetic acid
CAS 2350460-04-5C24H27NO4
3-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid chemical structure, C26H30N2O6, CAS 2171920-06-0
3-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid
CAS 2171920-06-0C26H30N2O6
3-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)-2-methylpropanoic acid chemical structure, C28H34N2O5, CAS 2171915-39-0
3-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)-2-methylpropanoic acid
CAS 2171915-39-0C28H34N2O5
(2R)-2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid chemical structure, C28H34N2O5, CAS 2171280-94-5
(2R)-2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid
CAS 2171280-94-5C28H34N2O5
4-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxybutanoic acid chemical structure, C27H32N2O6, CAS 2172116-77-5
4-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxybutanoic acid
CAS 2172116-77-5C27H32N2O6
(2R)-2-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)-3-hydroxypropanoic acid chemical structure, C27H32N2O6, CAS 2171168-40-2
(2R)-2-(2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}acetamido)-3-hydroxypropanoic acid
CAS 2171168-40-2C27H32N2O6
1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-(2-methylbutan-2-yl)cyclohexane-1-carboxylic acid chemical structure, C28H35NO4, CAS 2137858-57-0
1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-(2-methylbutan-2-yl)cyclohexane-1-carboxylic acid
CAS 2137858-57-0C28H35NO4
4-tert-Butyl-1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexane-1-carboxylic acid chemical structure, C27H33NO4, CAS 2138025-22-4
4-tert-Butyl-1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexane-1-carboxylic acid
CAS 2138025-22-4C27H33NO4
1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-propylcyclohexane-1-carboxylic acid chemical structure, C26H31NO4, CAS 2137678-68-1
1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-propylcyclohexane-1-carboxylic acid
CAS 2137678-68-1C26H31NO4