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Murcko scaffold

2-(Piperidin-4-yl)pyridine scaffold

331 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
331
With full pages
18
Scaffold SMILES

c1ccc(C2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)pyridine page
Murcko scaffold c1ccc(C2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 331 chemicals

tert-Butyl 4-(3-(trifluoromethyl)pyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H21F3N2O2, CAS 946399-74-2
tert-Butyl 4-(3-(trifluoromethyl)pyridin-2-yl)piperidine-1-carboxylate
CAS 946399-74-2C16H21F3N2O2
5-Bromo-2-(piperidin-4-yl)pyridine chemical structure, C10H13BrN2, CAS 845788-60-5
5-Bromo-2-(piperidin-4-yl)pyridine
CAS 845788-60-5C10H13BrN2
6-(4-Piperidinyl)-3-pyridinecarboxamide chemical structure, C11H15N3O, CAS 845788-62-7
6-(4-Piperidinyl)-3-pyridinecarboxamide
CAS 845788-62-7C11H15N3O
5-Bromo-2-(1-methylpiperidin-4-yl)pyridine chemical structure, C11H15BrN2, CAS 1226985-43-8
5-Bromo-2-(1-methylpiperidin-4-yl)pyridine
CAS 1226985-43-8C11H15BrN2
tert-Butyl 4-hydroxy-4-(3-(hydroxymethyl)pyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H24N2O4, CAS 909034-72-6
tert-Butyl 4-hydroxy-4-(3-(hydroxymethyl)pyridin-2-yl)piperidine-1-carboxylate
CAS 909034-72-6C16H24N2O4
3-Chloro-2-(4-piperidinyl)pyridine chemical structure, C10H13ClN2, CAS 899356-99-1
3-Chloro-2-(4-piperidinyl)pyridine
CAS 899356-99-1C10H13ClN2
1-(Propylsulfonyl)-4-(2-pyridinyl)-4-piperidinemethanamine chemical structure, C14H23N3O2S, CAS 866559-83-3
1-(Propylsulfonyl)-4-(2-pyridinyl)-4-piperidinemethanamine
CAS 866559-83-3C14H23N3O2S
4-(6-(Trifluoromethyl)pyridin-2-yl)piperidin-4-ol chemical structure, C11H13F3N2O, CAS 957999-59-6
4-(6-(Trifluoromethyl)pyridin-2-yl)piperidin-4-ol
CAS 957999-59-6C11H13F3N2O
1-Boc-4-[6-(trifluoromethyl)-2-pyridyl]piperidin-4-ol chemical structure, C16H21F3N2O3, CAS 957999-58-5
1-Boc-4-[6-(trifluoromethyl)-2-pyridyl]piperidin-4-ol
CAS 957999-58-5C16H21F3N2O3
tert-Butyl 4-(5-aminopyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H23N3O2, CAS 885693-48-1
tert-Butyl 4-(5-aminopyridin-2-yl)piperidine-1-carboxylate
CAS 885693-48-1C15H23N3O2
1,1-Dimethylethyl 4-(5-amino-6-bromo-2-pyridinyl)-1-piperidinecarboxylate chemical structure, C15H22BrN3O2, CAS 885693-49-2
1,1-Dimethylethyl 4-(5-amino-6-bromo-2-pyridinyl)-1-piperidinecarboxylate
CAS 885693-49-2C15H22BrN3O2
3-Fluoro-2-(piperidin-4-yl)pyridine chemical structure, C10H13FN2, CAS 1239205-61-8
3-Fluoro-2-(piperidin-4-yl)pyridine
CAS 1239205-61-8C10H13FN2
4-(3-Fluoro-2-pyridinyl)-4-piperidinecarbonitrile chemical structure, C11H12FN3, CAS 1239205-62-9
4-(3-Fluoro-2-pyridinyl)-4-piperidinecarbonitrile
CAS 1239205-62-9C11H12FN3
tert-Butyl 4-(3-hydroxypyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H22N2O3, CAS 1104082-76-9
tert-Butyl 4-(3-hydroxypyridin-2-yl)piperidine-1-carboxylate
CAS 1104082-76-9C15H22N2O3
tert-Butyl 4-(5-fluoro-3-hydroxypyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H21FN2O3, CAS 1104082-98-5
tert-Butyl 4-(5-fluoro-3-hydroxypyridin-2-yl)piperidine-1-carboxylate
CAS 1104082-98-5C15H21FN2O3
tert-Butyl 4-(3-fluoro-2-pyridinyl)piperidine-1-carboxylate chemical structure, C15H21FN2O2, CAS 1104082-44-1
tert-Butyl 4-(3-fluoro-2-pyridinyl)piperidine-1-carboxylate
CAS 1104082-44-1C15H21FN2O2
5-Bromo-2-(1-isopropylpiperidin-4-yl)pyridine chemical structure, C13H19BrN2, CAS 1093217-92-5
5-Bromo-2-(1-isopropylpiperidin-4-yl)pyridine
CAS 1093217-92-5C13H19BrN2
2-Methoxy-6-(piperidin-4-yl)pyridine chemical structure, C11H16N2O, CAS 899356-98-0
2-Methoxy-6-(piperidin-4-yl)pyridine
CAS 899356-98-0C11H16N2O
5-Fluoro-2-(piperidin-4-yl)pyridine chemical structure, C10H13FN2, CAS 1138217-86-3
5-Fluoro-2-(piperidin-4-yl)pyridine
CAS 1138217-86-3C10H13FN2
2-Fluoro-6-(piperidin-4-yl)pyridine chemical structure, C10H13FN2, CAS 1138217-83-0
2-Fluoro-6-(piperidin-4-yl)pyridine
CAS 1138217-83-0C10H13FN2
4-Methyl-2-(piperidin-4-yl)pyridine chemical structure, C11H16N2, CAS 1260886-47-2
4-Methyl-2-(piperidin-4-yl)pyridine
CAS 1260886-47-2C11H16N2
N-Methyl-6-piperidin-4-ylpyridin-2-amine dihydrochloride chemical structure, C11H17N3, CAS 1316222-04-4
N-Methyl-6-piperidin-4-ylpyridin-2-amine dihydrochloride
CAS 1316222-04-4C11H17N3
2-Bromo-6-(1-isopropylpiperidin-4-yl)pyridine chemical structure, C13H19BrN2, CAS 1316217-28-3
2-Bromo-6-(1-isopropylpiperidin-4-yl)pyridine
CAS 1316217-28-3C13H19BrN2
1-(4-(5-Bromopyridin-2-yl)piperidin-1-yl)ethanone chemical structure, C12H15BrN2O, CAS 1316221-39-2
1-(4-(5-Bromopyridin-2-yl)piperidin-1-yl)ethanone
CAS 1316221-39-2C12H15BrN2O