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Murcko scaffold

2-(Piperidin-4-yl)pyridine scaffold

331 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
331
With full pages
18
Scaffold SMILES

c1ccc(C2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)pyridine page
Murcko scaffold c1ccc(C2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 331 chemicals

tert-Butyl 4-(6-aminopyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H23N3O2, CAS 478366-40-4
tert-Butyl 4-(6-aminopyridin-2-yl)piperidine-1-carboxylate
CAS 478366-40-4C15H23N3O2
tert-Butyl 4-(5-cyanopyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H21N3O2, CAS 912556-76-4
tert-Butyl 4-(5-cyanopyridin-2-yl)piperidine-1-carboxylate
CAS 912556-76-4C16H21N3O2
tert-Butyl 4-(5-(trifluoromethyl)pyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H21F3N2O2, CAS 912556-86-6
tert-Butyl 4-(5-(trifluoromethyl)pyridin-2-yl)piperidine-1-carboxylate
CAS 912556-86-6C16H21F3N2O2
2-(Piperidin-4-yl)-5-(trifluoromethyl)pyridine chemical structure, C11H13F3N2, CAS 912556-78-6
2-(Piperidin-4-yl)-5-(trifluoromethyl)pyridine
CAS 912556-78-6C11H13F3N2
tert-Butyl 4-(hydroxymethyl)-4-(pyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H24N2O3, CAS 853576-51-9
tert-Butyl 4-(hydroxymethyl)-4-(pyridin-2-yl)piperidine-1-carboxylate
CAS 853576-51-9C16H24N2O3
tert-Butyl 4-cyano-4-(4-iodo-2-pyridyl)piperidine-1-carboxylate chemical structure, C16H20IN3O2, CAS 1196973-46-2
tert-Butyl 4-cyano-4-(4-iodo-2-pyridyl)piperidine-1-carboxylate
CAS 1196973-46-2C16H20IN3O2
2-Methyl-6-(piperidin-4-yl)pyridine chemical structure, C11H16N2, CAS 1256794-45-2
2-Methyl-6-(piperidin-4-yl)pyridine
CAS 1256794-45-2C11H16N2
4-(5-Bromo-3-chloro-2-pyridinyl)-4-fluoro-1-piperidinecarboxylic acid 1,1-dimethylethyl ester chemical structure, C15H19BrClFN2O2, CAS 1412943-67-9
4-(5-Bromo-3-chloro-2-pyridinyl)-4-fluoro-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
CAS 1412943-67-9C15H19BrClFN2O2
N-[6-(4-Piperidinyl)-3-pyridinyl]acetamide chemical structure, C12H17N3O, CAS 845788-65-0
N-[6-(4-Piperidinyl)-3-pyridinyl]acetamide
CAS 845788-65-0C12H17N3O
3-(6-Methyl-1',2',3',4',5',6'-hexahydro-[2,4']bipyridinyl-4-yl)-propionic acid ethyl ester dihydrochloride chemical structure, C16H26Cl2N2O2, CAS 1361112-01-7
3-(6-Methyl-1',2',3',4',5',6'-hexahydro-[2,4']bipyridinyl-4-yl)-propionic acid ethyl ester dihydrochloride
CAS 1361112-01-7C16H26Cl2N2O2
1'-Methanesulfonyl-1',2',3',4',5',6'-hexahydro-[2,4']bipyridinyl-5-carboxylic acid hydrochloride chemical structure, C12H17ClN2O4S, CAS 1361113-39-4
1'-Methanesulfonyl-1',2',3',4',5',6'-hexahydro-[2,4']bipyridinyl-5-carboxylic acid hydrochloride
CAS 1361113-39-4C12H17ClN2O4S
3-(6-(Piperidin-4-yl)pyridin-2-yl)propanamide dihydrochloride chemical structure, C13H21Cl2N3O, CAS 1361112-63-1
3-(6-(Piperidin-4-yl)pyridin-2-yl)propanamide dihydrochloride
CAS 1361112-63-1C13H21Cl2N3O
3-(1',2',3',4',5',6'-Hexahydro-[2,4']bipyridinyl-6-yl)-N,N-dimethyl-propionamide dihydrochloride chemical structure, C15H25Cl2N3O, CAS 1361114-27-3
3-(1',2',3',4',5',6'-Hexahydro-[2,4']bipyridinyl-6-yl)-N,N-dimethyl-propionamide dihydrochloride
CAS 1361114-27-3C15H25Cl2N3O
5-Methyl-2-(piperidin-4-yl)pyridine hydrochloride chemical structure, C11H17ClN2, CAS 1361116-83-7
5-Methyl-2-(piperidin-4-yl)pyridine hydrochloride
CAS 1361116-83-7C11H17ClN2
N-Methyl-6-(piperidin-4-yl)picolinamide dihydrochloride chemical structure, C12H19Cl2N3O, CAS 1361116-07-5
N-Methyl-6-(piperidin-4-yl)picolinamide dihydrochloride
CAS 1361116-07-5C12H19Cl2N3O
N,N-Dimethyl-6-(piperidin-4-yl)pyridin-2-amine dihydrochloride chemical structure, C12H21Cl2N3, CAS 1361115-15-2
N,N-Dimethyl-6-(piperidin-4-yl)pyridin-2-amine dihydrochloride
CAS 1361115-15-2C12H21Cl2N3
6-(2-Carboxy-ethyl)-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-carboxylic acid tert-butyl ester dihydrochloride chemical structure, C18H28Cl2N2O4, CAS 1361116-56-4
6-(2-Carboxy-ethyl)-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-carboxylic acid tert-butyl ester dihydrochloride
CAS 1361116-56-4C18H28Cl2N2O4
N-((6-(Piperidin-4-yl)pyridin-3-yl)methyl)acetamide dihydrochloride chemical structure, C13H21Cl2N3O, CAS 1361112-52-8
N-((6-(Piperidin-4-yl)pyridin-3-yl)methyl)acetamide dihydrochloride
CAS 1361112-52-8C13H21Cl2N3O
(1',2',3',4',5',6'-Hexahydro-[2,4']bipyridinyl-6-yl)-methyl-amine hydrochloride chemical structure, C11H18ClN3, CAS 1361115-22-1
(1',2',3',4',5',6'-Hexahydro-[2,4']bipyridinyl-6-yl)-methyl-amine hydrochloride
CAS 1361115-22-1C11H18ClN3
1-[1-Methyl-4-(pyridin-2-yl)piperidin-4-yl]propan-1-one chemical structure, C14H20N2O, CAS 134988-03-7
1-[1-Methyl-4-(pyridin-2-yl)piperidin-4-yl]propan-1-one
CAS 134988-03-7C14H20N2O
4-(Pyridin-2-yl)piperidine-4-carbonitrile dihydrochloride chemical structure, C11H15Cl2N3, CAS 1416439-49-0
4-(Pyridin-2-yl)piperidine-4-carbonitrile dihydrochloride
CAS 1416439-49-0C11H15Cl2N3
6-(Piperidin-4-yl)pyridin-3-ol chemical structure, C10H14N2O, CAS 1196156-23-6
6-(Piperidin-4-yl)pyridin-3-ol
CAS 1196156-23-6C10H14N2O
Ethyl 6-(piperidin-4-yl)nicotinate chemical structure, C13H18N2O2, CAS 1196147-46-2
Ethyl 6-(piperidin-4-yl)nicotinate
CAS 1196147-46-2C13H18N2O2
Methyl 6-(piperidin-4-yl)nicotinate chemical structure, C12H16N2O2, CAS 1196157-10-4
Methyl 6-(piperidin-4-yl)nicotinate
CAS 1196157-10-4C12H16N2O2