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Murcko scaffold

2-(Piperidin-4-yl)pyridine scaffold

331 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
331
With full pages
18
Scaffold SMILES

c1ccc(C2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)pyridine page
Murcko scaffold c1ccc(C2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 331 chemicals

3-Chloro-2-(piperidin-4-yl)pyridine dihydrochloride chemical structure, C10H15Cl3N2, CAS 1803608-41-4
3-Chloro-2-(piperidin-4-yl)pyridine dihydrochloride
CAS 1803608-41-4C10H15Cl3N2
4-Hydroxy-4-(2-pyridinyl)-1-piperidinecarbonyl chloride chemical structure, C11H13ClN2O2, CAS 957999-13-2
4-Hydroxy-4-(2-pyridinyl)-1-piperidinecarbonyl chloride
CAS 957999-13-2C11H13ClN2O2
6-(1-Methyl-4-piperidyl)pyridin-3-amine chemical structure, C11H17N3, CAS 1373421-18-1
6-(1-Methyl-4-piperidyl)pyridin-3-amine
CAS 1373421-18-1C11H17N3
2-(Piperidin-4-yl)pyridin-4-amine chemical structure, C10H15N3, CAS 1260856-38-9
2-(Piperidin-4-yl)pyridin-4-amine
CAS 1260856-38-9C10H15N3
tert-Butyl 4-(6-bromopyridin-2-yl)-4-(hydroxymethyl)piperidine-1-carboxylate chemical structure, C16H23BrN2O3, CAS 1415812-82-6
tert-Butyl 4-(6-bromopyridin-2-yl)-4-(hydroxymethyl)piperidine-1-carboxylate
CAS 1415812-82-6C16H23BrN2O3
2-(Piperidin-4-yl)-6-(propan-2-yloxy)pyridine chemical structure, C13H20N2O, CAS 1448682-32-3
2-(Piperidin-4-yl)-6-(propan-2-yloxy)pyridine
CAS 1448682-32-3C13H20N2O
2-Ethoxy-6-piperidin-4-ylpyridine chemical structure, C12H18N2O, CAS 1448682-33-4
2-Ethoxy-6-piperidin-4-ylpyridine
CAS 1448682-33-4C12H18N2O
tert-Butyl 4-(3-methoxypyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H24N2O3, CAS 1621910-27-7
tert-Butyl 4-(3-methoxypyridin-2-yl)piperidine-1-carboxylate
CAS 1621910-27-7C16H24N2O3
2-(Piperidin-4-yl)isonicotinonitrile chemical structure, C11H13N3, CAS 1260639-67-5
2-(Piperidin-4-yl)isonicotinonitrile
CAS 1260639-67-5C11H13N3
6-(Piperidin-4-yl)picolinonitrile chemical structure, C11H13N3, CAS 1256817-65-8
6-(Piperidin-4-yl)picolinonitrile
CAS 1256817-65-8C11H13N3
tert-Butyl 4-(3-aminopyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H23N3O2, CAS 873000-10-3
tert-Butyl 4-(3-aminopyridin-2-yl)piperidine-1-carboxylate
CAS 873000-10-3C15H23N3O2
tert-Butyl 4-(5-nitro-2-pyridinyl)piperidine-1-carboxylate chemical structure, C15H21N3O4, CAS 1085841-76-4
tert-Butyl 4-(5-nitro-2-pyridinyl)piperidine-1-carboxylate
CAS 1085841-76-4C15H21N3O4
2-(1-((1,1-Dimethylethoxy)carbonyl)-4-piperidinyl)-6-methyl-3-pyridinecarboxylic acid chemical structure, C17H24N2O4, CAS 521302-70-5
2-(1-((1,1-Dimethylethoxy)carbonyl)-4-piperidinyl)-6-methyl-3-pyridinecarboxylic acid
CAS 521302-70-5C17H24N2O4
1',2',3',4',5',6'-Hexahydro-[2,4']bipyridinyl-6-carboxylic acid dimethylamide chemical structure, C13H19N3O, CAS 1316222-34-0
1',2',3',4',5',6'-Hexahydro-[2,4']bipyridinyl-6-carboxylic acid dimethylamide
CAS 1316222-34-0C13H19N3O
2-(4-Fluoropiperidin-4-yl)pyridine dihydrochloride chemical structure, C10H15Cl2FN2, CAS 1803604-45-6
2-(4-Fluoropiperidin-4-yl)pyridine dihydrochloride
CAS 1803604-45-6C10H15Cl2FN2
4-Ethyl-2-(piperidin-4-yl)pyridine chemical structure, C12H18N2, CAS 1892335-62-4
4-Ethyl-2-(piperidin-4-yl)pyridine
CAS 1892335-62-4C12H18N2
(6-(1-Methylpiperidin-4-yl)pyridin-3-yl)methanamine chemical structure, C12H19N3, CAS 1895319-03-5
(6-(1-Methylpiperidin-4-yl)pyridin-3-yl)methanamine
CAS 1895319-03-5C12H19N3
6-(1-Methylpiperidin-4-yl)pyridine-3-carboxylic acid chemical structure, C12H16N2O2, CAS 1888989-50-1
6-(1-Methylpiperidin-4-yl)pyridine-3-carboxylic acid
CAS 1888989-50-1C12H16N2O2
tert-Butyl 4-[5-(aminomethyl)pyridin-2-yl]piperidine-1-carboxylate chemical structure, C16H25N3O2, CAS 1888759-39-4
tert-Butyl 4-[5-(aminomethyl)pyridin-2-yl]piperidine-1-carboxylate
CAS 1888759-39-4C16H25N3O2
tert-Butyl 4-(4-methylpyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H24N2O2, CAS 1638968-10-1
tert-Butyl 4-(4-methylpyridin-2-yl)piperidine-1-carboxylate
CAS 1638968-10-1C16H24N2O2
tert-Butyl 4-hydroxy-4-(3-(hydroxymethyl)-6-methylpyridin-2-yl)piperidine-1-carboxylate chemical structure, C17H26N2O4, CAS 1799924-01-8
tert-Butyl 4-hydroxy-4-(3-(hydroxymethyl)-6-methylpyridin-2-yl)piperidine-1-carboxylate
CAS 1799924-01-8C17H26N2O4
tert-Butyl 4-(5-amino-6-ethoxypyridin-2-yl)piperidine-1-carboxylate chemical structure, C17H27N3O3, CAS 1802180-69-3
tert-Butyl 4-(5-amino-6-ethoxypyridin-2-yl)piperidine-1-carboxylate
CAS 1802180-69-3C17H27N3O3
2-Piperidin-4-ylpyridin-3-ol, dihydrochloride chemical structure, C10H16Cl2N2O, CAS 1803352-67-1
2-Piperidin-4-ylpyridin-3-ol, dihydrochloride
CAS 1803352-67-1C10H16Cl2N2O
4-[5-(Hydroxymethyl)-4-methyl-2-pyridinyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester chemical structure, C17H26N2O3, CAS 1889326-68-4
4-[5-(Hydroxymethyl)-4-methyl-2-pyridinyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
CAS 1889326-68-4C17H26N2O3