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Murcko scaffold

Ring system with 3 rings and 18 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
15
With full pages
5
Scaffold SMILES

c1ccc(Sc2ccnn2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Sc2ccnn2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

3-Methyl-5-[(4-methylphenyl)sulfanyl]-1-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C18H16N2OS, CAS 308298-47-7
3-Methyl-5-[(4-methylphenyl)sulfanyl]-1-phenyl-1H-pyrazole-4-carbaldehyde
CAS 308298-47-7C18H16N2OS
5-(4-Chlorophenyl)sulfanyl-3-methyl-1-phenylpyrazole-4-carbaldehyde chemical structure, C17H13ClN2OS, CAS 380471-89-6
5-(4-Chlorophenyl)sulfanyl-3-methyl-1-phenylpyrazole-4-carbaldehyde
CAS 380471-89-6C17H13ClN2OS
Methyl 5-[(4-chlorophenyl)sulfanyl]-4-formyl-1-phenyl-1H-pyrazole-3-carboxylate chemical structure, C18H13ClN2O3S, CAS 449778-53-4
Methyl 5-[(4-chlorophenyl)sulfanyl]-4-formyl-1-phenyl-1H-pyrazole-3-carboxylate
CAS 449778-53-4C18H13ClN2O3S
Methyl 5-[(4-chlorophenyl)sulfanyl]-4-cyano-1-phenyl-1H-pyrazole-3-carboxylate chemical structure, C18H12ClN3O2S, CAS 956324-48-4
Methyl 5-[(4-chlorophenyl)sulfanyl]-4-cyano-1-phenyl-1H-pyrazole-3-carboxylate
CAS 956324-48-4C18H12ClN3O2S
Methyl 4-[(hydroxyimino)methyl]-5-[(4-methoxyphenyl)sulfanyl]-1-phenyl-1H-pyrazole-3-carboxylate chemical structure, C19H17N3O4S, CAS 318237-98-8
Methyl 4-[(hydroxyimino)methyl]-5-[(4-methoxyphenyl)sulfanyl]-1-phenyl-1H-pyrazole-3-carboxylate
CAS 318237-98-8C19H17N3O4S
Methyl 4-[(hydroxyimino)methyl]-5-[(4-methylphenyl)sulfanyl]-1-phenyl-1H-pyrazole-3-carboxylate chemical structure, C19H17N3O3S, CAS 318238-01-6
Methyl 4-[(hydroxyimino)methyl]-5-[(4-methylphenyl)sulfanyl]-1-phenyl-1H-pyrazole-3-carboxylate
CAS 318238-01-6C19H17N3O3S
Methyl 4-[(hydroxyimino)methyl]-1-phenyl-5-(phenylsulfanyl)-1H-pyrazole-3-carboxylate chemical structure, C18H15N3O3S, CAS 318238-02-7
Methyl 4-[(hydroxyimino)methyl]-1-phenyl-5-(phenylsulfanyl)-1H-pyrazole-3-carboxylate
CAS 318238-02-7C18H15N3O3S
Methyl 4-[(hydroxyimino)methyl]-1-phenyl-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1H-pyrazole-3-carboxylate chemical structure, C19H14F3N3O3S, CAS 318238-04-9
Methyl 4-[(hydroxyimino)methyl]-1-phenyl-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1H-pyrazole-3-carboxylate
CAS 318238-04-9C19H14F3N3O3S
Methyl 4-[(hydroxyimino)methyl]-5-{[2-(methoxycarbonyl)phenyl]sulfanyl}-1-phenyl-1H-pyrazole-3-carboxylate chemical structure, C20H17N3O5S, CAS 318238-00-5
Methyl 4-[(hydroxyimino)methyl]-5-{[2-(methoxycarbonyl)phenyl]sulfanyl}-1-phenyl-1H-pyrazole-3-carboxylate
CAS 318238-00-5C20H17N3O5S
Methyl 5-[(4-bromophenyl)sulfanyl]-4-[(hydroxyimino)methyl]-1-phenyl-1H-pyrazole-3-carboxylate chemical structure, C18H14BrN3O3S, CAS 318238-03-8
Methyl 5-[(4-bromophenyl)sulfanyl]-4-[(hydroxyimino)methyl]-1-phenyl-1H-pyrazole-3-carboxylate
CAS 318238-03-8C18H14BrN3O3S
Methyl 5-[(4-chlorophenyl)sulfanyl]-4-[(hydroxyimino)methyl]-1-phenyl-1H-pyrazole-3-carboxylate chemical structure, C18H14ClN3O3S, CAS 318237-99-9
Methyl 5-[(4-chlorophenyl)sulfanyl]-4-[(hydroxyimino)methyl]-1-phenyl-1H-pyrazole-3-carboxylate
CAS 318237-99-9C18H14ClN3O3S
1-(3-Chlorophenyl)-5-[(4-chlorophenyl)thio]-3-methyl-1H-pyrazole-4-carbaldehyde chemical structure, C17H12Cl2N2OS, CAS 895881-67-1
1-(3-Chlorophenyl)-5-[(4-chlorophenyl)thio]-3-methyl-1H-pyrazole-4-carbaldehyde
CAS 895881-67-1C17H12Cl2N2OS
4-Formyl-1-phenyl-5-(phenylthio)-3-(trifluoromethyl)pyrazole chemical structure, C17H11F3N2OS, CAS 1284226-40-9
4-Formyl-1-phenyl-5-(phenylthio)-3-(trifluoromethyl)pyrazole
CAS 1284226-40-9C17H11F3N2OS
Ethyl 5-[(3-bromophenyl)thio]-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylate chemical structure, C18H14BrClN2O2S, CAS 1138037-21-4
Ethyl 5-[(3-bromophenyl)thio]-1-(2-chlorophenyl)-1H-pyrazole-3-carboxylate
CAS 1138037-21-4C18H14BrClN2O2S
Ethyl 5-[(3-methoxyphenyl)thio]-1-(2-methylphenyl)-1H-pyrazole-3-carboxylate chemical structure, C20H20N2O3S, CAS 1138037-15-6
Ethyl 5-[(3-methoxyphenyl)thio]-1-(2-methylphenyl)-1H-pyrazole-3-carboxylate
CAS 1138037-15-6C20H20N2O3S