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Murcko scaffold

Ring system with 3 rings and 20 atoms

70 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
70
With full pages
19
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN=C1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN=C1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 70 chemicals

1-(2-Methoxy-5-methylphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole chemical structure, C17H18N2O3S, CAS 723743-84-8
1-(2-Methoxy-5-methylphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole
CAS 723743-84-8C17H18N2O3S
1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C17H17ClN2O2S, CAS 723744-49-8
1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole
CAS 723744-49-8C17H17ClN2O2S
1-(4-Fluorophenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole chemical structure, C15H13FN2O2S, CAS 723744-51-2
1-(4-Fluorophenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole
CAS 723744-51-2C15H13FN2O2S
1-[(3,4-Dimethylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C17H18N2O2S, CAS 723745-01-5
1-[(3,4-Dimethylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole
CAS 723745-01-5C17H18N2O2S
1-((4-Fluoro-3-methoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C16H15FN2O3S, CAS 717892-66-5
1-((4-Fluoro-3-methoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 717892-66-5C16H15FN2O3S
1-(Mesitylsulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C18H20N2O2S, CAS 708228-85-7
1-(Mesitylsulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 708228-85-7C18H20N2O2S
1-[(4-Ethoxyphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C17H18N2O3S, CAS 708242-51-7
1-[(4-Ethoxyphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole
CAS 708242-51-7C17H18N2O3S
1-[(4-Methoxy-2,5-dimethylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C18H20N2O3S, CAS 708242-57-3
1-[(4-Methoxy-2,5-dimethylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole
CAS 708242-57-3C18H20N2O3S
2-Phenyl-1-[(2,4,5-trimethylphenyl)sulfonyl]-4,5-dihydro-1H-imidazole chemical structure, C18H20N2O2S, CAS 701288-64-4
2-Phenyl-1-[(2,4,5-trimethylphenyl)sulfonyl]-4,5-dihydro-1H-imidazole
CAS 701288-64-4C18H20N2O2S
1-((4-Chloro-2,5-dimethoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C17H17ClN2O4S, CAS 701276-49-5
1-((4-Chloro-2,5-dimethoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 701276-49-5C17H17ClN2O4S
1-((4-Bromo-2,5-dimethoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C17H17BrN2O4S, CAS 701952-26-3
1-((4-Bromo-2,5-dimethoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 701952-26-3C17H17BrN2O4S
1-[(5-Chloro-2-methoxyphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C16H15ClN2O3S, CAS 708223-83-0
1-[(5-Chloro-2-methoxyphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole
CAS 708223-83-0C16H15ClN2O3S
1-[(4-Chloro-3-methoxyphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C16H15ClN2O3S, CAS 723743-87-1
1-[(4-Chloro-3-methoxyphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole
CAS 723743-87-1C16H15ClN2O3S
1-((2,4-Dichloro-3-methylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C16H14Cl2N2O2S, CAS 723744-53-4
1-((2,4-Dichloro-3-methylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 723744-53-4C16H14Cl2N2O2S
1-((2,4-Dichloro-5-methylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C16H14Cl2N2O2S, CAS 723745-03-7
1-((2,4-Dichloro-5-methylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 723745-03-7C16H14Cl2N2O2S
1-((4-Ethoxy-2,3-dimethylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C19H22N2O3S, CAS 717892-97-2
1-((4-Ethoxy-2,3-dimethylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 717892-97-2C19H22N2O3S
N-{4-[(2-Phenyl-4,5-dihydro-1H-imidazol-1-yl)sulfonyl]phenyl}acetamide chemical structure, C17H17N3O3S, CAS 695209-29-1
N-{4-[(2-Phenyl-4,5-dihydro-1H-imidazol-1-yl)sulfonyl]phenyl}acetamide
CAS 695209-29-1C17H17N3O3S
1-(5-Bromo-2-methoxyphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole chemical structure, C16H15BrN2O3S, CAS 701929-62-6
1-(5-Bromo-2-methoxyphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole
CAS 701929-62-6C16H15BrN2O3S
1-(2,5-Dichloro-4-methoxyphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole chemical structure, C16H14Cl2N2O3S, CAS 701944-49-2
1-(2,5-Dichloro-4-methoxyphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole
CAS 701944-49-2C16H14Cl2N2O3S
1-[(4-Fluoro-3-methylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C16H15FN2O2S, CAS 708235-58-9
1-[(4-Fluoro-3-methylphenyl)sulfonyl]-2-phenyl-4,5-dihydro-1H-imidazole
CAS 708235-58-9C16H15FN2O2S
1-((4-Chloro-3-ethoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C17H17ClN2O3S, CAS 713500-85-7
1-((4-Chloro-3-ethoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 713500-85-7C17H17ClN2O3S
1-((4-Ethoxy-3-methylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C18H20N2O3S, CAS 832685-79-7
1-((4-Ethoxy-3-methylphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 832685-79-7C18H20N2O3S
1-(4-Methoxyphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole chemical structure, C16H16N2O3S, CAS 915888-31-2
1-(4-Methoxyphenyl)sulfonyl-2-phenyl-4,5-dihydroimidazole
CAS 915888-31-2C16H16N2O3S
1-((5-Fluoro-2-methoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole chemical structure, C16H15FN2O3S, CAS 873580-23-5
1-((5-Fluoro-2-methoxyphenyl)sulfonyl)-2-phenyl-4,5-dihydro-1H-imidazole
CAS 873580-23-5C16H15FN2O3S