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Murcko scaffold

Ring system with 3 rings and 20 atoms

95 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
95
With full pages
8
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCSC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCSC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 95 chemicals

N-{4-[2-(4-Chloro-phenyl)-thiazolidine-3-sulfonyl]-phenyl}-acetamide chemical structure, C17H17ClN2O3S2, CAS 799257-61-7
N-{4-[2-(4-Chloro-phenyl)-thiazolidine-3-sulfonyl]-phenyl}-acetamide
CAS 799257-61-7C17H17ClN2O3S2
3-(4-Fluoro-benzenesulfonyl)-2-(2,4,5-trimethoxy-phenyl)-thiazolidine chemical structure, C18H20FNO5S2, CAS 441738-23-4
3-(4-Fluoro-benzenesulfonyl)-2-(2,4,5-trimethoxy-phenyl)-thiazolidine
CAS 441738-23-4C18H20FNO5S2
2-(4-Chlorophenyl)-3-(4-methylphenyl)sulfonyl-1,3-thiazolidine chemical structure, C16H16ClNO2S2, CAS 312615-52-4
2-(4-Chlorophenyl)-3-(4-methylphenyl)sulfonyl-1,3-thiazolidine
CAS 312615-52-4C16H16ClNO2S2
2-(3-Chlorophenyl)-3-((4-ethoxyphenyl)sulfonyl)thiazolidine chemical structure, C17H18ClNO3S2, CAS 397283-62-4
2-(3-Chlorophenyl)-3-((4-ethoxyphenyl)sulfonyl)thiazolidine
CAS 397283-62-4C17H18ClNO3S2
3-((4-Bromophenyl)sulfonyl)-2-(4-methoxyphenyl)thiazolidine chemical structure, C16H16BrNO3S2, CAS 397283-64-6
3-((4-Bromophenyl)sulfonyl)-2-(4-methoxyphenyl)thiazolidine
CAS 397283-64-6C16H16BrNO3S2
2-(3,4-Dimethoxyphenyl)-3-((4-ethoxyphenyl)sulfonyl)thiazolidine chemical structure, C19H23NO5S2, CAS 418810-47-6
2-(3,4-Dimethoxyphenyl)-3-((4-ethoxyphenyl)sulfonyl)thiazolidine
CAS 418810-47-6C19H23NO5S2
3-(Benzenesulfonyl)-2-(3-nitrophenyl)-1,3-thiazolidine chemical structure, C15H14N2O4S2, CAS 313267-69-5
3-(Benzenesulfonyl)-2-(3-nitrophenyl)-1,3-thiazolidine
CAS 313267-69-5C15H14N2O4S2
2-(4-Bromophenyl)-3-((4-ethoxyphenyl)sulfonyl)thiazolidine chemical structure, C17H18BrNO3S2, CAS 397283-92-0
2-(4-Bromophenyl)-3-((4-ethoxyphenyl)sulfonyl)thiazolidine
CAS 397283-92-0C17H18BrNO3S2
2-(2-Methoxyphenyl)-3-(m-tolylsulfonyl)thiazolidine chemical structure, C17H19NO3S2, CAS 397283-55-5
2-(2-Methoxyphenyl)-3-(m-tolylsulfonyl)thiazolidine
CAS 397283-55-5C17H19NO3S2
2-(5-Bromo-2-methoxyphenyl)-3-(m-tolylsulfonyl)thiazolidine chemical structure, C17H18BrNO3S2, CAS 321579-25-3
2-(5-Bromo-2-methoxyphenyl)-3-(m-tolylsulfonyl)thiazolidine
CAS 321579-25-3C17H18BrNO3S2
2-(3,4-Dimethoxyphenyl)-3-(4-methylbenzenesulfonyl)-1,3-thiazolidine chemical structure, C18H21NO4S2, CAS 312615-54-6
2-(3,4-Dimethoxyphenyl)-3-(4-methylbenzenesulfonyl)-1,3-thiazolidine
CAS 312615-54-6C18H21NO4S2
2-(3-Nitrophenyl)-3-(m-tolylsulfonyl)thiazolidine chemical structure, C16H16N2O4S2, CAS 397283-68-0
2-(3-Nitrophenyl)-3-(m-tolylsulfonyl)thiazolidine
CAS 397283-68-0C16H16N2O4S2
3-((4-Chlorophenyl)sulfonyl)-2-(4-methoxyphenyl)thiazolidine chemical structure, C16H16ClNO3S2, CAS 319490-53-4
3-((4-Chlorophenyl)sulfonyl)-2-(4-methoxyphenyl)thiazolidine
CAS 319490-53-4C16H16ClNO3S2
2-(3,4-Dimethoxyphenyl)-3-((4-methyl-3-nitrophenyl)sulfonyl)thiazolidine chemical structure, C18H20N2O6S2, CAS 337353-79-4
2-(3,4-Dimethoxyphenyl)-3-((4-methyl-3-nitrophenyl)sulfonyl)thiazolidine
CAS 337353-79-4C18H20N2O6S2
3-(4-Chlorophenyl)sulfonyl-2-(2,4,5-trimethoxyphenyl)-1,3-thiazolidine chemical structure, C18H20ClNO5S2, CAS 397284-03-6
3-(4-Chlorophenyl)sulfonyl-2-(2,4,5-trimethoxyphenyl)-1,3-thiazolidine
CAS 397284-03-6C18H20ClNO5S2
2-(4-Chloro-phenyl)-3-(4-methyl-3-nitro-benzenesulfonyl)-thiazolidine chemical structure, C16H15ClN2O4S2, CAS 337353-77-2
2-(4-Chloro-phenyl)-3-(4-methyl-3-nitro-benzenesulfonyl)-thiazolidine
CAS 337353-77-2C16H15ClN2O4S2
3-(4-Methyl-3-nitrophenyl)sulfonyl-2-phenyl-1,3-thiazolidine chemical structure, C16H16N2O4S2, CAS 337353-82-9
3-(4-Methyl-3-nitrophenyl)sulfonyl-2-phenyl-1,3-thiazolidine
CAS 337353-82-9C16H16N2O4S2
3-(4-Methoxy-benzenesulfonyl)-2-(4-nitro-phenyl)-thiazolidine chemical structure, C16H16N2O5S2, CAS 337353-33-0
3-(4-Methoxy-benzenesulfonyl)-2-(4-nitro-phenyl)-thiazolidine
CAS 337353-33-0C16H16N2O5S2
2-(4-Bromophenyl)-3-((4-methyl-3-nitrophenyl)sulfonyl)thiazolidine chemical structure, C16H15BrN2O4S2, CAS 397284-47-8
2-(4-Bromophenyl)-3-((4-methyl-3-nitrophenyl)sulfonyl)thiazolidine
CAS 397284-47-8C16H15BrN2O4S2
2-(2-Chlorophenyl)-3-((4-methoxyphenyl)sulfonyl)thiazolidine chemical structure, C16H16ClNO3S2, CAS 337505-00-7
2-(2-Chlorophenyl)-3-((4-methoxyphenyl)sulfonyl)thiazolidine
CAS 337505-00-7C16H16ClNO3S2
2-(4-Nitro-phenyl)-3-(toluene-3-sulfonyl)-thiazolidine chemical structure, C16H16N2O4S2, CAS 333435-88-4
2-(4-Nitro-phenyl)-3-(toluene-3-sulfonyl)-thiazolidine
CAS 333435-88-4C16H16N2O4S2
3-(Benzenesulfonyl)-2-(4-chlorophenyl)-1,3-thiazolidine chemical structure, C15H14ClNO2S2, CAS 5474-16-8
3-(Benzenesulfonyl)-2-(4-chlorophenyl)-1,3-thiazolidine
CAS 5474-16-8C15H14ClNO2S2
3-(4-Bromo-benzenesulfonyl)-2-(3-nitro-phenyl)-thiazolidine chemical structure, C15H13BrN2O4S2, CAS 312943-51-4
3-(4-Bromo-benzenesulfonyl)-2-(3-nitro-phenyl)-thiazolidine
CAS 312943-51-4C15H13BrN2O4S2
3-(m-Tolylsulfonyl)-2-(2,4,5-trimethoxyphenyl)thiazolidine chemical structure, C19H23NO5S2, CAS 337353-41-0
3-(m-Tolylsulfonyl)-2-(2,4,5-trimethoxyphenyl)thiazolidine
CAS 337353-41-0C19H23NO5S2