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Murcko scaffold

Ring system with 2 rings and 12 atoms

25 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
25
With full pages
0
Scaffold SMILES

O=C1CCCC(c2cn[nH]c2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC(c2cn[nH]c2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1311316-52-5
1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxylic acid
CAS 1311316-52-5C11H15N3O3
1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxamide chemical structure, C11H16N4O2, CAS 1315366-28-9
1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxamide
CAS 1315366-28-9C11H16N4O2
5-Amino-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C9H14N4O, CAS 1334147-74-8
5-Amino-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 1334147-74-8C9H14N4O
1-Ethyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1496200-27-1
1-Ethyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxylic acid
CAS 1496200-27-1C12H17N3O3
(5S)-5-Amino-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C9H14N4O, CAS 1375830-21-9
(5S)-5-Amino-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 1375830-21-9C9H14N4O
rac-(5R,6S)-5-Amino-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C9H14N4O, CAS 1807938-72-2
rac-(5R,6S)-5-Amino-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 1807938-72-2C9H14N4O
Rac-(5R,6S)-5-amino-6-(1-ethyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C10H16N4O, CAS 1807940-60-8
Rac-(5R,6S)-5-amino-6-(1-ethyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 1807940-60-8C10H16N4O
1-Ethyl-N-methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxamide chemical structure, C13H20N4O2, CAS 1803570-55-9
1-Ethyl-N-methyl-2-(1-methyl-1H-pyrazol-4-yl)-6-oxopiperidine-3-carboxamide
CAS 1803570-55-9C13H20N4O2
1-Methyl-6-oxo-2-(1H-pyrazol-4-yl)piperidine-3-carboxylic acid chemical structure, C10H13N3O3, CAS 1707562-84-2
1-Methyl-6-oxo-2-(1H-pyrazol-4-yl)piperidine-3-carboxylic acid
CAS 1707562-84-2C10H13N3O3
6-Oxo-2-(1H-pyrazol-4-yl)piperidine-3-carboxylic acid chemical structure, C9H11N3O3, CAS 1710345-33-7
6-Oxo-2-(1H-pyrazol-4-yl)piperidine-3-carboxylic acid
CAS 1710345-33-7C9H11N3O3
2-(1-Ethyl-1H-pyrazol-4-yl)-1-methyl-6-oxopiperidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1779127-35-3
2-(1-Ethyl-1H-pyrazol-4-yl)-1-methyl-6-oxopiperidine-3-carboxylic acid
CAS 1779127-35-3C12H17N3O3
1-Methyl-6-oxo-2-(1-propyl-1H-pyrazol-4-yl)piperidine-3-carboxylic acid chemical structure, C13H19N3O3, CAS 1779127-38-6
1-Methyl-6-oxo-2-(1-propyl-1H-pyrazol-4-yl)piperidine-3-carboxylic acid
CAS 1779127-38-6C13H19N3O3
5-Amino-6-(1-ethyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C10H16N4O, CAS 1690433-86-3
5-Amino-6-(1-ethyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 1690433-86-3C10H16N4O
6-(3,5-Dimethyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C10H15N3O, CAS 1367676-20-7
6-(3,5-Dimethyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 1367676-20-7C10H15N3O
rac-(5R,6S)-5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C11H18N4O, CAS 2137726-95-3
rac-(5R,6S)-5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 2137726-95-3C11H18N4O
(5R,6S)-5-(Aminomethyl)-1-ethyl-6-(1-methylpyrazol-4-yl)piperidin-2-one chemical structure, C12H20N4O, CAS 2137611-70-0
(5R,6S)-5-(Aminomethyl)-1-ethyl-6-(1-methylpyrazol-4-yl)piperidin-2-one
CAS 2137611-70-0C12H20N4O
(2S,4S)-2-(1-Methylpyrazol-4-yl)-6-oxopiperidine-4-carboxylic acid chemical structure, C10H13N3O3, CAS 2243516-62-1
(2S,4S)-2-(1-Methylpyrazol-4-yl)-6-oxopiperidine-4-carboxylic acid
CAS 2243516-62-1C10H13N3O3
2-Chloro-N-[(2S,3R)-2-(1-methylpyrazol-4-yl)-6-oxopiperidin-3-yl]acetamide chemical structure, C11H15ClN4O2, CAS 2411177-68-7
2-Chloro-N-[(2S,3R)-2-(1-methylpyrazol-4-yl)-6-oxopiperidin-3-yl]acetamide
CAS 2411177-68-7C11H15ClN4O2
2-Chloro-N-[[(2S,3R)-1-ethyl-2-(1-methylpyrazol-4-yl)-6-oxopiperidin-3-yl]methyl]propanamide chemical structure, C15H23ClN4O2, CAS 2411183-71-4
2-Chloro-N-[[(2S,3R)-1-ethyl-2-(1-methylpyrazol-4-yl)-6-oxopiperidin-3-yl]methyl]propanamide
CAS 2411183-71-4C15H23ClN4O2
2-Chloro-N-[(2S,3R)-2-(1-ethylpyrazol-4-yl)-6-oxopiperidin-3-yl]propanamide chemical structure, C13H19ClN4O2, CAS 2411183-97-4
2-Chloro-N-[(2S,3R)-2-(1-ethylpyrazol-4-yl)-6-oxopiperidin-3-yl]propanamide
CAS 2411183-97-4C13H19ClN4O2
rac-(5R,6S)-5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one, trifluoroacetic acid chemical structure, C13H19F3N4O3, CAS 2137726-96-4
rac-(5R,6S)-5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one, trifluoroacetic acid
CAS 2137726-96-4C13H19F3N4O3
5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one, trifluoroacetic acid chemical structure, C13H19F3N4O3, CAS 2137708-66-6
5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one, trifluoroacetic acid
CAS 2137708-66-6C13H19F3N4O3
5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C11H18N4O, CAS 2137564-47-5
5-(Aminomethyl)-1-methyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 2137564-47-5C11H18N4O
5-(Aminomethyl)-1-ethyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one chemical structure, C12H20N4O, CAS 2137768-53-5
5-(Aminomethyl)-1-ethyl-6-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one
CAS 2137768-53-5C12H20N4O