Murcko scaffold
Ring system with 3 rings and 25 atoms
158 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 25
- Chemicals
- 158
- With full pages
- 4
Scaffold SMILES
O=C(NCCc1cnc(-c2ccccc2)s1)C(=O)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 158 chemicals
N1-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)-N2-phenyloxalamide
CAS 894010-82-3C20H19N3O2S
N1-(2,5-dimethylphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide
CAS 894011-32-6C22H23N3O2S
N1-(3-chloro-2-methylphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide
CAS 894012-09-0C21H20ClN3O2S
N1-(2-(4-methyl-2-(p-tolyl)thiazol-5-yl)ethyl)-N2-(m-tolyl)oxalamide
CAS 894012-70-5C22H23N3O2S
N1-(3-fluoro-4-methylphenyl)-N2-(2-(4-methyl-2-(p-tolyl)thiazol-5-yl)ethyl)oxalamide
CAS 894014-42-7C22H22FN3O2S
![N-{2-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-phenylethanediamide chemical structure, C20H18ClN3O2S, CAS 895800-75-6](/s/IVGPQFARXWDLRT-UHFFFAOYSA-N.svg)
N-{2-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-phenylethanediamide
CAS 895800-75-6C20H18ClN3O2S
![N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methylphenyl)ethanediamide chemical structure, C21H20FN3O2S, CAS 895801-90-8](/s/RLPLTPHRQYIFCN-UHFFFAOYSA-N.svg)
N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methylphenyl)ethanediamide
CAS 895801-90-8C21H20FN3O2S
![N'-(3,5-Dimethylphenyl)-N-[2-[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide chemical structure, C22H22FN3O2S, CAS 895801-96-4](/s/DVZAIOYALVDKAC-UHFFFAOYSA-N.svg)
N'-(3,5-Dimethylphenyl)-N-[2-[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide
CAS 895801-96-4C22H22FN3O2S
N1-(2-fluorophenyl)-N2-(2-(2-(4-fluorophenyl)-4-methylthiazol-5-yl)ethyl)oxalamide
CAS 895802-02-5C20H17F2N3O2S
N1-(3-fluorophenyl)-N2-(2-(2-(4-fluorophenyl)-4-methylthiazol-5-yl)ethyl)oxalamide
CAS 895802-21-8C20H17F2N3O2S
![N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methoxyphenyl)ethanediamide chemical structure, C21H20FN3O3S, CAS 895802-26-3](/s/OTYSGFMIPFCADZ-UHFFFAOYSA-N.svg)
N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methoxyphenyl)ethanediamide
CAS 895802-26-3C21H20FN3O3S
![N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-phenylethanediamide chemical structure, C20H18FN3O2S, CAS 895802-35-4](/s/BXOFJKPLLOUJJY-UHFFFAOYSA-N.svg)
N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-phenylethanediamide
CAS 895802-35-4C20H18FN3O2S
![N'-(2,6-Dimethylphenyl)-N-[2-[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide chemical structure, C22H22FN3O2S, CAS 895802-41-2](/s/CKASOKUHUKDNAG-UHFFFAOYSA-N.svg)
N'-(2,6-Dimethylphenyl)-N-[2-[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide
CAS 895802-41-2C22H22FN3O2S
![N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-methoxyphenyl)ethanediamide chemical structure, C21H20FN3O3S, CAS 895802-44-5](/s/ZZYFVNRYBZDUPI-UHFFFAOYSA-N.svg)
N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-methoxyphenyl)ethanediamide
CAS 895802-44-5C21H20FN3O3S
![N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-methylphenyl)ethanediamide chemical structure, C21H20FN3O2S, CAS 895802-50-3](/s/VMIICANPHSKDLU-UHFFFAOYSA-N.svg)
N-{2-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-methylphenyl)ethanediamide
CAS 895802-50-3C21H20FN3O2S
![N'-(2,5-Dimethylphenyl)-N-[2-[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide chemical structure, C22H22FN3O2S, CAS 895802-62-7](/s/LMHFNLSPMUVJDT-UHFFFAOYSA-N.svg)
N'-(2,5-Dimethylphenyl)-N-[2-[2-(4-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide
CAS 895802-62-7C22H22FN3O2S
N1-(2-ethylphenyl)-N2-(2-(2-(4-fluorophenyl)-4-methylthiazol-5-yl)ethyl)oxalamide
CAS 895803-06-2C22H22FN3O2S
![N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methylphenyl)ethanediamide chemical structure, C21H20FN3O2S, CAS 895803-71-1](/s/JGTLFSAOIYKSAO-UHFFFAOYSA-N.svg)
N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methylphenyl)ethanediamide
CAS 895803-71-1C21H20FN3O2S
![N'-(3,5-Dimethylphenyl)-N-[2-[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide chemical structure, C22H22FN3O2S, CAS 895803-77-7](/s/NOVRLUWIVVUIMS-UHFFFAOYSA-N.svg)
N'-(3,5-Dimethylphenyl)-N-[2-[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide
CAS 895803-77-7C22H22FN3O2S
N1-(3-fluorophenyl)-N2-(2-(2-(3-fluorophenyl)-4-methylthiazol-5-yl)ethyl)oxalamide
CAS 895804-02-1C20H17F2N3O2S
![N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methoxyphenyl)ethanediamide chemical structure, C21H20FN3O3S, CAS 895804-07-6](/s/OOJZSVIFYUYRNJ-UHFFFAOYSA-N.svg)
N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(3-methoxyphenyl)ethanediamide
CAS 895804-07-6C21H20FN3O3S
N1-(4-ethylphenyl)-N2-(2-(2-(3-fluorophenyl)-4-methylthiazol-5-yl)ethyl)oxalamide
CAS 895804-12-3C22H22FN3O2S
![N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-phenylethanediamide chemical structure, C20H18FN3O2S, CAS 895804-17-8](/s/GKGXUIKCEGQUMD-UHFFFAOYSA-N.svg)
N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-phenylethanediamide
CAS 895804-17-8C20H18FN3O2S
![N'-(2,6-Dimethylphenyl)-N-[2-[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide chemical structure, C22H22FN3O2S, CAS 895804-28-1](/s/DGIWKPGFPPMPLV-UHFFFAOYSA-N.svg)
N'-(2,6-Dimethylphenyl)-N-[2-[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide
CAS 895804-28-1C22H22FN3O2S
- N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-methoxyphenyl)ethanediamide895804-35-0C21H20FN3O3S
- N-{2-[2-(3-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl}-N'-(2-methylphenyl)ethanediamide895804-48-5C21H20FN3O2S
- N'-(2,4-Dimethylphenyl)-N-[2-[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide895804-60-1C22H22FN3O2S
- N'-(2,5-Dimethylphenyl)-N-[2-[2-(3-fluorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl]oxamide895804-66-7C22H22FN3O2S
- N1-(3-fluoro-4-methylphenyl)-N2-(2-(2-(3-fluorophenyl)-4-methylthiazol-5-yl)ethyl)oxalamide895778-21-9C21H19F2N3O2S
- N1-(4-methoxyphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894009-97-3C21H21N3O3S
- N1-(4-chlorophenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894010-03-8C20H18ClN3O2S
- N1-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)-N2-(p-tolyl)oxalamide894010-09-4C21H21N3O2S
- N1-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)-N2-(m-tolyl)oxalamide894010-22-1C21H21N3O2S
- N1-(2-cyanophenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894010-34-5C21H18N4O2S
- N1-(4-fluorophenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894010-54-9C20H18FN3O2S
- N1-(3-fluorophenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894010-61-8C20H18FN3O2S
- N1-(3-methoxyphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894010-68-5C21H21N3O3S
- N1-(2,3-dimethylphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894010-89-0C22H23N3O2S
- N'-(2-Chlorophenyl)-N-[2-(4-methyl-2-phenyl-1,3-thiazol-5-yl)ethyl]ethanediamide894011-08-6C20H18ClN3O2S
- N-[2-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)ethyl]-N'-(4-nitrophenyl)ethanediamide894011-38-2C20H18N4O4S
- N1-(2-methoxy-5-methylphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894011-44-0C22H23N3O3S
- N1-(3-fluoro-4-methylphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894011-86-0C21H20FN3O2S
- N-[2-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)ethyl]-N'-(2-nitrophenyl)ethanediamide894012-20-5C20H18N4O4S
- N1-(2-ethoxyphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894012-26-1C22H23N3O3S
- N1-(3-chloro-4-methylphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894012-32-9C21H20ClN3O2S
- N1-(5-chloro-2-methylphenyl)-N2-(2-(4-methyl-2-phenylthiazol-5-yl)ethyl)oxalamide894012-37-4C21H20ClN3O2S
- N-[2-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)ethyl]-N'-(3-nitrophenyl)ethanediamide894012-43-2C20H18N4O4S
- N-{2-[4-Methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]ethyl}-N'-(4-methylphenyl)ethanediamide894012-59-0C22H23N3O2S
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