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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,537 to 1,584 of 2,195 chemicals

6-(1-Methoxyethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C10H11N3O3, CAS 2654760-86-6
6-(1-Methoxyethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 2654760-86-6C10H11N3O3
6-Bromo-3-fluoro-2-methyl-pyrazolo[1,5-a]pyrimidine chemical structure, C7H5BrFN3, CAS 2638501-65-0
6-Bromo-3-fluoro-2-methyl-pyrazolo[1,5-a]pyrimidine
CAS 2638501-65-0C7H5BrFN3
3-Bromo-5-chloro-6-methoxypyrazolo[1,5-a]pyrimidine chemical structure, C7H5BrClN3O, CAS 2681395-23-1
3-Bromo-5-chloro-6-methoxypyrazolo[1,5-a]pyrimidine
CAS 2681395-23-1C7H5BrClN3O
3-Bromo-5-chloro-6-(methoxymethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C8H7BrClN3O, CAS 2681395-30-0
3-Bromo-5-chloro-6-(methoxymethyl)pyrazolo[1,5-a]pyrimidine
CAS 2681395-30-0C8H7BrClN3O
3-Bromo-5-chloro-6-fluoropyrazolo[1,5-a]pyrimidine chemical structure, C6H2BrClFN3, CAS 2681395-31-1
3-Bromo-5-chloro-6-fluoropyrazolo[1,5-a]pyrimidine
CAS 2681395-31-1C6H2BrClFN3
Ethyl 6-methoxypyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H11N3O3, CAS 2106349-82-8
Ethyl 6-methoxypyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2106349-82-8C10H11N3O3
Methyl 7-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H11N3O2, CAS 1352884-18-4
Methyl 7-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1352884-18-4C10H11N3O2
3-Iodo-N,N-dimethyl-pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C8H9IN4, CAS 2688841-54-3
3-Iodo-N,N-dimethyl-pyrazolo[1,5-a]pyrimidin-7-amine
CAS 2688841-54-3C8H9IN4
Methyl 5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C9H6F3N3O2, CAS 2112450-70-9
Methyl 5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2112450-70-9C9H6F3N3O2
3-Iodo-7-isopropylpyrazolo[1,5-a]pyrimidine chemical structure, C9H10IN3, CAS 2688841-52-1
3-Iodo-7-isopropylpyrazolo[1,5-a]pyrimidine
CAS 2688841-52-1C9H10IN3
5,7-Dibromo-3-fluoro-pyrazolo[1,5-a]pyrimidine chemical structure, C6H2Br2FN3, CAS 2735695-67-5
5,7-Dibromo-3-fluoro-pyrazolo[1,5-a]pyrimidine
CAS 2735695-67-5C6H2Br2FN3
5,7-Dichloro-3-fluoropyrazolo[1,5-A]pyrimidine chemical structure, C6H2Cl2FN3, CAS 2735700-55-5
5,7-Dichloro-3-fluoropyrazolo[1,5-A]pyrimidine
CAS 2735700-55-5C6H2Cl2FN3
5-Amino-2-bromoPyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C7H4BrN5, CAS 2738608-14-3
5-Amino-2-bromoPyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 2738608-14-3C7H4BrN5
2-Bromo-5-chloro-pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C7H2BrClN4, CAS 2738608-88-1
2-Bromo-5-chloro-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 2738608-88-1C7H2BrClN4
2-Bromo-5-chloroPyrazolo[1,5-a]pyrimidine-3-carboxaldehyde chemical structure, C7H3BrClN3O, CAS 2738608-11-0
2-Bromo-5-chloroPyrazolo[1,5-a]pyrimidine-3-carboxaldehyde
CAS 2738608-11-0C7H3BrClN3O
Ethyl 5-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-2-carboxylate chemical structure, C10H8F3N3O2, CAS 2701535-36-4
Ethyl 5-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-2-carboxylate
CAS 2701535-36-4C10H8F3N3O2
5,7-Dichloro-2-methoxypyrazolo[1,5-a]pyrimidine chemical structure, C7H5Cl2N3O, CAS 2730453-37-7
5,7-Dichloro-2-methoxypyrazolo[1,5-a]pyrimidine
CAS 2730453-37-7C7H5Cl2N3O
5-Chloro-2-fluoro-3-nitropyrazolo[1,5-a]pyrimidine chemical structure, C6H2ClFN4O2, CAS 2734856-00-7
5-Chloro-2-fluoro-3-nitropyrazolo[1,5-a]pyrimidine
CAS 2734856-00-7C6H2ClFN4O2
2,5,7-Trimethylpyrazolo[1,5-a]pyrimidin-6-ol chemical structure, C9H11N3O, CAS 2749532-91-8
2,5,7-Trimethylpyrazolo[1,5-a]pyrimidin-6-ol
CAS 2749532-91-8C9H11N3O
tert-Butyl (5-chloropyrazolo[1,5-a]pyrimidin-3-yl)carbamate chemical structure, C11H13ClN4O2, CAS 2770348-31-5
tert-Butyl (5-chloropyrazolo[1,5-a]pyrimidin-3-yl)carbamate
CAS 2770348-31-5C11H13ClN4O2
Ethyl 3-amino-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C10H12N4O2, CAS 2222465-59-8
Ethyl 3-amino-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 2222465-59-8C10H12N4O2
Ethyl 5,7-dichloro-3-isopropylpyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C12H13Cl2N3O2, CAS 2760415-25-4
Ethyl 5,7-dichloro-3-isopropylpyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 2760415-25-4C12H13Cl2N3O2
Pyrazolo[1,5-a]pyrimidine-6-carbohydrazide chemical structure, C7H7N5O, CAS 2639625-63-9
Pyrazolo[1,5-a]pyrimidine-6-carbohydrazide
CAS 2639625-63-9C7H7N5O
Methyl 7-(2-methoxy-2-oxoethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C11H11N3O4, CAS 2986918-64-1
Methyl 7-(2-methoxy-2-oxoethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 2986918-64-1C11H11N3O4