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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,489 to 1,536 of 2,195 chemicals

Ethyl 5-chloro-6-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C9H8ClN3O3, CAS 2359663-69-5
Ethyl 5-chloro-6-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2359663-69-5C9H8ClN3O3
Ethyl 5-chloro-6-methoxypyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H10ClN3O3, CAS 2359663-72-0
Ethyl 5-chloro-6-methoxypyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2359663-72-0C10H10ClN3O3
5-(Difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-amine chemical structure, C7H6F2N4, CAS 2573213-97-3
5-(Difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-amine
CAS 2573213-97-3C7H6F2N4
6-MethoxyPyrazolo[1,5-a]pyrimidin-3-amine chemical structure, C7H8N4O, CAS 2573152-16-4
6-MethoxyPyrazolo[1,5-a]pyrimidin-3-amine
CAS 2573152-16-4C7H8N4O
6-Fluoropyrazolo[1,5-a]pyrimidin-3-amine chemical structure, C6H5FN4, CAS 2168177-53-3
6-Fluoropyrazolo[1,5-a]pyrimidin-3-amine
CAS 2168177-53-3C6H5FN4
6-Fluoropyrazolo[1,5-a]pyrimidin-3-amine hydrochloride chemical structure, C6H6ClFN4, CAS 2573150-78-2
6-Fluoropyrazolo[1,5-a]pyrimidin-3-amine hydrochloride
CAS 2573150-78-2C6H6ClFN4
6-(Difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-amine chemical structure, C7H6F2N4, CAS 2573213-87-1
6-(Difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-amine
CAS 2573213-87-1C7H6F2N4
N-(5-Chloropyrazolo[1,5-a]pyrimidin-2-yl)acetamide chemical structure, C8H7ClN4O, CAS 2711726-91-7
N-(5-Chloropyrazolo[1,5-a]pyrimidin-2-yl)acetamide
CAS 2711726-91-7C8H7ClN4O
tert-Butyl 6-formylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C12H13N3O3, CAS 2470435-28-8
tert-Butyl 6-formylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2470435-28-8C12H13N3O3
Methyl 3-aminopyrazolo[1,5-a]pyrimidine-6-carboxylate, hydrochloride chemical structure, C8H9ClN4O2, CAS 2470439-24-6
Methyl 3-aminopyrazolo[1,5-a]pyrimidine-6-carboxylate, hydrochloride
CAS 2470439-24-6C8H9ClN4O2
Methyl 7-chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylate chemical structure, C9H7ClIN3O2, CAS 2490405-99-5
Methyl 7-chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylate
CAS 2490405-99-5C9H7ClIN3O2
N-(3-Amino-4-methylpentyl)-3-chloro-N-methylpyrazolo[1,5-a]pyrimidine-2-carboxamide, dihydrochloride chemical structure, C14H22Cl3N5O, CAS 2490406-14-7
N-(3-Amino-4-methylpentyl)-3-chloro-N-methylpyrazolo[1,5-a]pyrimidine-2-carboxamide, dihydrochloride
CAS 2490406-14-7C14H22Cl3N5O
3-Pyrazolo[1,5-a]pyrimidin-6-ylpropan-1-amine, dihydrochloride chemical structure, C9H14Cl2N4, CAS 2551114-94-2
3-Pyrazolo[1,5-a]pyrimidin-6-ylpropan-1-amine, dihydrochloride
CAS 2551114-94-2C9H14Cl2N4
2-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propanoic acid chemical structure, C10H9BrClN3O2, CAS 2387601-09-2
2-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propanoic acid
CAS 2387601-09-2C10H9BrClN3O2
2-(7-Chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)-2-methylpropan-1-ol chemical structure, C11H14ClN3O, CAS 2387596-87-2
2-(7-Chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)-2-methylpropan-1-ol
CAS 2387596-87-2C11H14ClN3O
2-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)acetic acid chemical structure, C9H7BrClN3O2, CAS 2387596-07-6
2-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)acetic acid
CAS 2387596-07-6C9H7BrClN3O2
3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidine-5-carbaldehyde chemical structure, C8H5BrClN3O, CAS 2387601-53-6
3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidine-5-carbaldehyde
CAS 2387601-53-6C8H5BrClN3O
7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C8H5ClIN3O2, CAS 2387601-50-3
7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 2387601-50-3C8H5ClIN3O2
2-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)butan-1-ol chemical structure, C11H13BrClN3O, CAS 2387598-94-7
2-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)butan-1-ol
CAS 2387598-94-7C11H13BrClN3O
2-(7-Chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)butan-1-ol chemical structure, C11H14ClN3O, CAS 2387599-35-9
2-(7-Chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)butan-1-ol
CAS 2387599-35-9C11H14ClN3O
Ethyl 2-(7-chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propanoate chemical structure, C12H13ClIN3O2, CAS 2387601-22-9
Ethyl 2-(7-chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propanoate
CAS 2387601-22-9C12H13ClIN3O2
2-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propanoic acid chemical structure, C10H9ClIN3O2, CAS 2387600-74-8
2-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propanoic acid
CAS 2387600-74-8C10H9ClIN3O2
7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carbaldehyde chemical structure, C8H5ClIN3O, CAS 2387598-81-2
7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carbaldehyde
CAS 2387598-81-2C8H5ClIN3O
2-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)-2-methylpropan-1-ol chemical structure, C11H13ClIN3O, CAS 2387600-30-6
2-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)-2-methylpropan-1-ol
CAS 2387600-30-6C11H13ClIN3O