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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,777 to 1,824 of 2,195 chemicals

tert-Butyl N-methyl-N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-yl)carbamate chemical structure, C15H20N4O3, CAS 2228394-68-9
tert-Butyl N-methyl-N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-yl)carbamate
CAS 2228394-68-9C15H20N4O3
4,4,4-Trifluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}butanoic acid chemical structure, C10H8F3N3O2, CAS 2228639-32-3
4,4,4-Trifluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}butanoic acid
CAS 2228639-32-3C10H8F3N3O2
(2S)-1-{Pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-ol chemical structure, C9H11N3O, CAS 2227710-28-1
(2S)-1-{Pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-ol
CAS 2227710-28-1C9H11N3O
3-Methyl-3-{pyrazolo[1,5-a]pyrimidin-2-yl}butan-1-amine chemical structure, C11H16N4, CAS 2229124-99-4
3-Methyl-3-{pyrazolo[1,5-a]pyrimidin-2-yl}butan-1-amine
CAS 2229124-99-4C11H16N4
Methyl (3S)-3-hydroxy-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propanoate chemical structure, C10H11N3O3, CAS 2227723-15-9
Methyl (3S)-3-hydroxy-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propanoate
CAS 2227723-15-9C10H11N3O3
2-{Pyrazolo[1,5-a]pyrimidin-6-yloxy}acetic acid chemical structure, C8H7N3O3, CAS 2228841-75-4
2-{Pyrazolo[1,5-a]pyrimidin-6-yloxy}acetic acid
CAS 2228841-75-4C8H7N3O3
2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-amine chemical structure, C10H14N4, CAS 2229013-31-2
2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-amine
CAS 2229013-31-2C10H14N4
(1S)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-amine chemical structure, C8H10N4, CAS 2227813-93-4
(1S)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-amine
CAS 2227813-93-4C8H10N4
2,2-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid chemical structure, C9H7F2N3O2, CAS 2229441-36-3
2,2-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid
CAS 2229441-36-3C9H7F2N3O2
2-Amino-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2228279-23-8
2-Amino-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
CAS 2228279-23-8C9H12N4O
(1R)-2-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol chemical structure, C8H10N4O, CAS 2227848-46-4
(1R)-2-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol
CAS 2227848-46-4C8H10N4O
(2R)-4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-amine chemical structure, C10H14N4, CAS 2227726-90-9
(2R)-4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-amine
CAS 2227726-90-9C10H14N4
2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine chemical structure, C10H14N4, CAS 2229223-05-4
2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine
CAS 2229223-05-4C10H14N4
3-Bromo-6-iodopyrazolo[1,5-a]pyrimidine chemical structure, C6H3BrIN3, CAS 2743438-58-4
3-Bromo-6-iodopyrazolo[1,5-a]pyrimidine
CAS 2743438-58-4C6H3BrIN3
4,4-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}butanoic acid chemical structure, C10H9F2N3O2, CAS 2228294-95-7
4,4-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}butanoic acid
CAS 2228294-95-7C10H9F2N3O2
3,3-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine chemical structure, C9H10F2N4, CAS 2229578-34-9
3,3-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine
CAS 2229578-34-9C9H10F2N4
6-(Isocyanatomethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C8H6N4O, CAS 2649074-84-8
6-(Isocyanatomethyl)pyrazolo[1,5-a]pyrimidine
CAS 2649074-84-8C8H6N4O
2-(2-Nitroethenyl)pyrazolo[1,5-a]pyrimidine chemical structure, C8H6N4O2, CAS 2229658-19-7
2-(2-Nitroethenyl)pyrazolo[1,5-a]pyrimidine
CAS 2229658-19-7C8H6N4O2
(2S)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine chemical structure, C9H12N4, CAS 2227886-69-1
(2S)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine
CAS 2227886-69-1C9H12N4
O-(1-{Pyrazolo[1,5-a]pyrimidin-2-yl}ethyl)hydroxylamine chemical structure, C8H10N4O, CAS 2228857-13-2
O-(1-{Pyrazolo[1,5-a]pyrimidin-2-yl}ethyl)hydroxylamine
CAS 2228857-13-2C8H10N4O
O-(2-{Pyrazolo[1,5-a]pyrimidin-6-yl}propyl)hydroxylamine chemical structure, C9H12N4O, CAS 2229229-83-6
O-(2-{Pyrazolo[1,5-a]pyrimidin-6-yl}propyl)hydroxylamine
CAS 2229229-83-6C9H12N4O
2-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine chemical structure, C9H12N4, CAS 2228499-55-4
2-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine
CAS 2228499-55-4C9H12N4
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-amine chemical structure, C8H7F3N4, CAS 2228962-21-6
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-amine
CAS 2228962-21-6C8H7F3N4
(1R)-3-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2227818-70-2
(1R)-3-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
CAS 2227818-70-2C9H12N4O