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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,825 to 1,872 of 2,195 chemicals

6-(1-Bromopropan-2-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H10BrN3, CAS 2228354-73-0
6-(1-Bromopropan-2-yl)pyrazolo[1,5-a]pyrimidine
CAS 2228354-73-0C9H10BrN3
3,3,3-Trifluoro-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine chemical structure, C9H9F3N4, CAS 2228356-72-5
3,3,3-Trifluoro-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine
CAS 2228356-72-5C9H9F3N4
N-Methyl-N-({pyrazolo[1,5-a]pyrimidin-2-yl}methyl)hydroxylamine chemical structure, C8H10N4O, CAS 2228219-34-7
N-Methyl-N-({pyrazolo[1,5-a]pyrimidin-2-yl}methyl)hydroxylamine
CAS 2228219-34-7C8H10N4O
2-Oxo-2-{pyrazolo[1,5-a]pyrimidin-6-yl}acetic acid chemical structure, C8H5N3O3, CAS 2228878-68-8
2-Oxo-2-{pyrazolo[1,5-a]pyrimidin-6-yl}acetic acid
CAS 2228878-68-8C8H5N3O3
tert-Butyl N-(2-oxo-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethyl)carbamate chemical structure, C13H16N4O3, CAS 2229084-91-5
tert-Butyl N-(2-oxo-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethyl)carbamate
CAS 2229084-91-5C13H16N4O3
(1S)-2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol chemical structure, C8H6F3N3O, CAS 2227725-98-4
(1S)-2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
CAS 2227725-98-4C8H6F3N3O
2-Amino-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2229377-34-6
2-Amino-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
CAS 2229377-34-6C9H12N4O
(2R)-4-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-2-ol chemical structure, C10H13N3O, CAS 2227825-08-1
(2R)-4-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-2-ol
CAS 2227825-08-1C10H13N3O
1-{Pyrazolo[1,5-a]pyrimidin-6-yl}prop-2-en-1-ol chemical structure, C9H9N3O, CAS 2229614-69-9
1-{Pyrazolo[1,5-a]pyrimidin-6-yl}prop-2-en-1-ol
CAS 2229614-69-9C9H9N3O
(2S)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-ol chemical structure, C9H11N3O, CAS 2227726-25-0
(2S)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-ol
CAS 2227726-25-0C9H11N3O
(1S)-2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol chemical structure, C8H6F3N3O, CAS 2227825-39-8
(1S)-2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol
CAS 2227825-39-8C8H6F3N3O
1-Amino-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-ol chemical structure, C9H12N4O, CAS 2229117-24-0
1-Amino-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-ol
CAS 2229117-24-0C9H12N4O
O-(2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propyl)hydroxylamine chemical structure, C10H14N4O, CAS 2229323-41-3
O-(2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propyl)hydroxylamine
CAS 2229323-41-3C10H14N4O
2,2-Difluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol chemical structure, C8H7F2N3O, CAS 2228883-82-5
2,2-Difluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol
CAS 2228883-82-5C8H7F2N3O
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol chemical structure, C8H6F3N3O, CAS 2228753-08-8
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol
CAS 2228753-08-8C8H6F3N3O
2-(Isocyanatomethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C8H6N4O, CAS 2649003-94-9
2-(Isocyanatomethyl)pyrazolo[1,5-a]pyrimidine
CAS 2649003-94-9C8H6N4O
2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol chemical structure, C10H13N3O, CAS 2229191-13-1
2-Methyl-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol
CAS 2229191-13-1C10H13N3O
2-Amino-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2229098-20-6
2-Amino-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol
CAS 2229098-20-6C9H12N4O
2,2-Dimethyl-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine chemical structure, C11H16N4, CAS 2228260-15-7
2,2-Dimethyl-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine
CAS 2228260-15-7C11H16N4
tert-Butyl N-methyl-N-(2-oxo-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethyl)carbamate chemical structure, C14H18N4O3, CAS 2229546-56-7
tert-Butyl N-methyl-N-(2-oxo-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethyl)carbamate
CAS 2229546-56-7C14H18N4O3
4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-ol chemical structure, C10H13N3O, CAS 2229395-06-4
4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-ol
CAS 2229395-06-4C10H13N3O
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-1-amine chemical structure, C10H14N4, CAS 2228379-13-1
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-1-amine
CAS 2228379-13-1C10H14N4
Methyl(2-methyl-1-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-yl)amine chemical structure, C11H16N4, CAS 2228258-34-0
Methyl(2-methyl-1-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-yl)amine
CAS 2228258-34-0C11H16N4
3-{Pyrazolo[1,5-a]pyrimidin-6-yl}propane-1-thiol chemical structure, C9H11N3S, CAS 2229392-46-3
3-{Pyrazolo[1,5-a]pyrimidin-6-yl}propane-1-thiol
CAS 2229392-46-3C9H11N3S