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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 2,195 chemicals

1-(2-Methylpyrazolo[1,5-A]pyrimidin-6-yl)propan-2-one chemical structure, C10H11N3O, CAS 198349-38-1
1-(2-Methylpyrazolo[1,5-A]pyrimidin-6-yl)propan-2-one
CAS 198349-38-1C10H11N3O
7-Aminopyrazolo(1,5-a)pyrimidine chemical structure, C6H6N4, CAS 1194-63-4
7-Aminopyrazolo(1,5-a)pyrimidine
CAS 1194-63-4C6H6N4
Pyrazolo[1,5-a]pyrimidin-7-amine, 5-(1-methylethyl)- chemical structure, C9H12N4, CAS 93669-75-1
Pyrazolo[1,5-a]pyrimidin-7-amine, 5-(1-methylethyl)-
CAS 93669-75-1C9H12N4
Pyrazolo[1,5-a]pyrimidine-3,7-diamine chemical structure, C6H7N5, CAS 201599-12-4
Pyrazolo[1,5-a]pyrimidine-3,7-diamine
CAS 201599-12-4C6H7N5
6-Bromo-2-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H6BrN3, CAS 916256-65-0
6-Bromo-2-methylpyrazolo[1,5-a]pyrimidine
CAS 916256-65-0C7H6BrN3
7-(Dimethoxymethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H11N3O2, CAS 930395-98-5
7-(Dimethoxymethyl)pyrazolo[1,5-a]pyrimidine
CAS 930395-98-5C9H11N3O2
3-{3-Cyano-5,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid chemical structure, C12H12N4O2, CAS 900137-38-4
3-{3-Cyano-5,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid
CAS 900137-38-4C12H12N4O2
Ethyl 6-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C9H8ClN3O2, CAS 936074-36-1
Ethyl 6-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 936074-36-1C9H8ClN3O2
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H4F3N3O2, CAS 869947-41-1
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 869947-41-1C8H4F3N3O2
3-Bromopyrazolo(1,5-a)pyrimidine-2-carboxylic acid chemical structure, C7H4BrN3O2, CAS 832740-60-0
3-Bromopyrazolo(1,5-a)pyrimidine-2-carboxylic acid
CAS 832740-60-0C7H4BrN3O2
6-Bromo-2-methylpyrazolo(1,5-a)pyrimidine-3-carbaldehyde chemical structure, C8H6BrN3O, CAS 899518-62-8
6-Bromo-2-methylpyrazolo(1,5-a)pyrimidine-3-carbaldehyde
CAS 899518-62-8C8H6BrN3O
Pyrazolo[1,5-a]pyrimidine-3-carboxamide chemical structure, C7H6N4O, CAS 774549-55-2
Pyrazolo[1,5-a]pyrimidine-3-carboxamide
CAS 774549-55-2C7H6N4O
3-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]acrylic acid chemical structure, C11H8F3N3O2, CAS 1613051-35-6
3-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]acrylic acid
CAS 1613051-35-6C11H8F3N3O2
Ethyl 3-cyanopyrazolo[1,5-a]pyrimidine-7-carboxylate chemical structure, C10H8N4O2, CAS 950057-07-5
Ethyl 3-cyanopyrazolo[1,5-a]pyrimidine-7-carboxylate
CAS 950057-07-5C10H8N4O2
{Pyrazolo[1,5-a]pyrimidin-7-yl}methanamine chemical structure, C7H8N4, CAS 930471-11-7
{Pyrazolo[1,5-a]pyrimidin-7-yl}methanamine
CAS 930471-11-7C7H8N4
5,7-Dimethylpyrazolo[1,5-A]pyrimidine-3-carboxamide chemical structure, C9H10N4O, CAS 43024-19-7
5,7-Dimethylpyrazolo[1,5-A]pyrimidine-3-carboxamide
CAS 43024-19-7C9H10N4O
3-Bromo-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine chemical structure, C9H7BrF3N3, CAS 954278-38-7
3-Bromo-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine
CAS 954278-38-7C9H7BrF3N3
5,7-Dichloro-3-ethylpyrazolo(1,5-a)pyrimidine chemical structure, C8H7Cl2N3, CAS 779353-64-9
5,7-Dichloro-3-ethylpyrazolo(1,5-a)pyrimidine
CAS 779353-64-9C8H7Cl2N3
2-[(3-Aminopyrazolo[1,5-a]pyrimidin-7-yl)amino]ethanol chemical structure, C8H11N5O, CAS 201599-21-5
2-[(3-Aminopyrazolo[1,5-a]pyrimidin-7-yl)amino]ethanol
CAS 201599-21-5C8H11N5O
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-sulfonyl chloride chemical structure, C8H8ClN3O2S, CAS 61552-52-1
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-sulfonyl chloride
CAS 61552-52-1C8H8ClN3O2S
(5-Methylpyrazolo[1,5-a]pyrimidin-3-yl)methanol chemical structure, C8H9N3O, CAS 1263060-50-9
(5-Methylpyrazolo[1,5-a]pyrimidin-3-yl)methanol
CAS 1263060-50-9C8H9N3O
2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-sulfonyl chloride chemical structure, C8H5ClF3N3O2S, CAS 1016515-74-4
2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-sulfonyl chloride
CAS 1016515-74-4C8H5ClF3N3O2S
7-Chloro-2,5-dimethylpyrazolo(1,5-a)pyrimidine chemical structure, C8H8ClN3, CAS 136549-13-8
7-Chloro-2,5-dimethylpyrazolo(1,5-a)pyrimidine
CAS 136549-13-8C8H8ClN3
6-Methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C8H7N3O2, CAS 889939-98-4
6-Methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 889939-98-4C8H7N3O2