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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 2,195 chemicals

3-{2,5,7-Trimethylpyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid chemical structure, C12H15N3O2, CAS 851116-09-1
3-{2,5,7-Trimethylpyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid
CAS 851116-09-1C12H15N3O2
3-Cyano-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C9H6N4O2, CAS 329207-47-8
3-Cyano-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 329207-47-8C9H6N4O2
5-tert-Butyl-N-(2-methylpropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide chemical structure, C16H21F3N4O, CAS 438224-81-8
5-tert-Butyl-N-(2-methylpropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
CAS 438224-81-8C16H21F3N4O
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-2,3-diamine chemical structure, C8H11N5, CAS 200884-04-4
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-2,3-diamine
CAS 200884-04-4C8H11N5
6-Acetyl-7-[(E)-2-(dimethylamino)ethenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C13H13N5O, CAS 130506-87-5
6-Acetyl-7-[(E)-2-(dimethylamino)ethenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 130506-87-5C13H13N5O
2-[1-Cyano-2-(dimethylamino)vinyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C14H14N6, CAS 338977-21-2
2-[1-Cyano-2-(dimethylamino)vinyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 338977-21-2C14H14N6
N-[(E)-[Amino-(2-methylpyrazolo[1,5-a]pyrimidin-6-yl)methylidene]amino]-2-cyanoacetamide chemical structure, C11H11N7O
N-[(E)-[Amino-(2-methylpyrazolo[1,5-a]pyrimidin-6-yl)methylidene]amino]-2-cyanoacetamide
C11H11N7O
2-[(1Z)-1-Cyano-2-(dimethylamino)eth-1-en-1-yl]-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C14H8F6N6, CAS 338786-57-5
2-[(1Z)-1-Cyano-2-(dimethylamino)eth-1-en-1-yl]-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 338786-57-5C14H8F6N6
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carbaldehyde chemical structure, C9H9N3O, CAS 878414-63-2
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carbaldehyde
CAS 878414-63-2C9H9N3O
6-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H7N3O2, CAS 869941-96-8
6-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 869941-96-8C8H7N3O2
Pyrazolo(1,5-a)pyrimidine-3-carbaldehyde chemical structure, C7H5N3O, CAS 879072-59-0
Pyrazolo(1,5-a)pyrimidine-3-carbaldehyde
CAS 879072-59-0C7H5N3O
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C8H3F3N4, CAS 832115-44-3
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 832115-44-3C8H3F3N4
Ethyl 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H11N3O2, CAS 832741-06-7
Ethyl 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 832741-06-7C10H11N3O2
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C8H4F3N3O2, CAS 869947-40-0
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 869947-40-0C8H4F3N3O2
3-Bromopyrazolo[1,5-a]pyrimidine-2-carbonyl chloride chemical structure, C7H3BrClN3O, CAS 861224-59-1
3-Bromopyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
CAS 861224-59-1C7H3BrClN3O
5-Methyl-7-(1,1,2,2,2-pentafluoroethyl)pyrazolo(1,5-a)pyrimidine chemical structure, C9H6F5N3, CAS 869951-80-4
5-Methyl-7-(1,1,2,2,2-pentafluoroethyl)pyrazolo(1,5-a)pyrimidine
CAS 869951-80-4C9H6F5N3
Ethyl pyrazolo(1,5-a)pyrimidine-3-carboxylate chemical structure, C9H9N3O2, CAS 115932-00-8
Ethyl pyrazolo(1,5-a)pyrimidine-3-carboxylate
CAS 115932-00-8C9H9N3O2
3-Bromo-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C9H5BrF3N3O2, CAS 832740-70-2
3-Bromo-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 832740-70-2C9H5BrF3N3O2
(Z)-N'-Hydroxy-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboximidamide chemical structure, C9H11N5O, CAS 61552-51-0
(Z)-N'-Hydroxy-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboximidamide
CAS 61552-51-0C9H11N5O
1-(2-Ethoxy-7-methylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone chemical structure, C11H13N3O2, CAS 159976-76-8
1-(2-Ethoxy-7-methylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone
CAS 159976-76-8C11H13N3O2
Ethyl 2-(1,1-dimethylethyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C14H19N3O2, CAS 162286-63-7
Ethyl 2-(1,1-dimethylethyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 162286-63-7C14H19N3O2
Ethyl 2-methoxy-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C11H13N3O3, CAS 162286-71-7
Ethyl 2-methoxy-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 162286-71-7C11H13N3O3
7-Chloro-5-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H6ClN3, CAS 16082-27-2
7-Chloro-5-methylpyrazolo[1,5-a]pyrimidine
CAS 16082-27-2C7H6ClN3
7-Chloro-3,5-dimethylpyrazolo(1,5-a)pyrimidine chemical structure, C8H8ClN3, CAS 244127-42-2
7-Chloro-3,5-dimethylpyrazolo(1,5-a)pyrimidine
CAS 244127-42-2C8H8ClN3