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Murcko scaffold

6,7,8,9-Tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one scaffold

102 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 102
With full pages: 7

Scaffold SMILES

O=c1ccnc2n1CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 6,7,8,9-Tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one page

Murcko scaffold O=c1ccnc2n1CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 102 chemicals

3-(2-Chloroethyl)-7-methoxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C12H17ClN2O2, CAS 130049-80-8

3-(2-Chloroethyl)-7-methoxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 130049-80-8C₁₂H₁₇ClN₂O₂

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one monohydrochloride chemical structure, C12H18Cl2N2O2, CAS 130049-81-9

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one monohydrochloride

CAS 130049-81-9C₁₂H₁₈Cl₂N₂O₂

3-(2-Chloroethyl)-9-hydroxy-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one chemical structure, C10H13ClN2O2, CAS 130049-77-3

3-(2-Chloroethyl)-9-hydroxy-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one

CAS 130049-77-3C₁₀H₁₃ClN₂O₂

4H-Pyrido[1,2-A]pyrimidin-3-carboxylic acid, 6,7 chemical structure, C10H12N2O3, CAS 80715-99-7

4H-Pyrido[1,2-A]pyrimidin-3-carboxylic acid, 6,7

CAS 80715-99-7C₁₀H₁₂N₂O₃

9-(Acetyloxy)-3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C13H17ClN2O3, CAS 1117803-76-5

9-(Acetyloxy)-3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 1117803-76-5C₁₃H₁₇ClN₂O₃

(S)-3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C11H15ClN2O2, CAS 1606138-65-1

(S)-3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 1606138-65-1C₁₁H₁₅ClN₂O₂

2-Methyl-3-(2-(methylamino)ethyl)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C12H19N3O, CAS 1144440-42-5

2-Methyl-3-(2-(methylamino)ethyl)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 1144440-42-5C₁₂H₁₉N₃O

3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride chemical structure, C11H16Cl2N2O2, CAS 849727-63-5

3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride

CAS 849727-63-5C₁₁H₁₆Cl₂N₂O₂

3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-A]pyrimidin-4-one chemical structure, C11H16N2O2, CAS 849903-79-3

3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-A]pyrimidin-4-one

CAS 849903-79-3C₁₁H₁₆N₂O₂

Methyl 3-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate chemical structure, C10H12N2O4, CAS 724445-24-3

Methyl 3-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylate

CAS 724445-24-3C₁₀H₁₂N₂O₄

Paliperidone IMpurity 07 chemical structure, C11H14N2O2, CAS 1008796-23-3

Paliperidone IMpurity 07

CAS 1008796-23-3C₁₁H₁₄N₂O₂

6,7,8,9-Tetrahydro-3-(2-iodoethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C11H15IN2O, CAS 885706-66-1

6,7,8,9-Tetrahydro-3-(2-iodoethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 885706-66-1C₁₁H₁₅IN₂O

3-(2-Chloroethyl-d4)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C11H15ClN2O, CAS 1189712-26-2

3-(2-Chloroethyl-d4)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 1189712-26-2C₁₁H₁₅ClN₂O

3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Hydrochloride chemical structure, C11H17ClN2O2, CAS 849727-64-6

3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Hydrochloride

CAS 849727-64-6C₁₁H₁₇ClN₂O₂

3-Ethenyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one chemical structure, C11H14N2O, CAS 832747-59-8

3-Ethenyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one

CAS 832747-59-8C₁₁H₁₄N₂O

1,3,6-Trimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-1-ium chemical structure, C11H17N2O+, CAS 54606-25-6

1,3,6-Trimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-1-ium

CAS 54606-25-6C₁₁H₁₇N₂O+

Paliperidone impurity 7 chemical structure, C27H45ClN2O3, CAS 1415488-05-9

Paliperidone impurity 7

CAS 1415488-05-9C₂₇H₄₅ClN₂O₃

9-Hydroxy-3-(2-hydroxyethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C11H16N2O3, CAS 1160915-55-8

9-Hydroxy-3-(2-hydroxyethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 1160915-55-8C₁₁H₁₆N₂O₃

3-(2-Aminoethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one dihydrochloride chemical structure, C11H19Cl2N3O, CAS 1333491-21-6

3-(2-Aminoethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one dihydrochloride

CAS 1333491-21-6C₁₁H₁₉Cl₂N₃O

4-Oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid chemical structure, C9H10N2O3, CAS 1551062-50-0

4-Oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid

CAS 1551062-50-0C₉H₁₀N₂O₃

(2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-3-yl)acetic acid chemical structure, C11H14N2O3, CAS 152542-01-3

(2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-3-yl)acetic acid

CAS 152542-01-3C₁₁H₁₄N₂O₃

4H-Pyrido(1,2-a)pyrimidine-3-acetic acid, 6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4-oxo- chemical structure, C11H14N2O4, CAS 152542-02-4

4H-Pyrido(1,2-a)pyrimidine-3-acetic acid, 6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4-oxo-

CAS 152542-02-4C₁₁H₁₄N₂O₄

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one N-Oxide chemical structure, C11H15ClN2O2, CAS 1797131-18-0

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one N-Oxide

CAS 1797131-18-0C₁₁H₁₅ClN₂O₂

2-(Difluoromethyl)-8,8-dimethyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C11H14F2N2O, CAS 2059940-67-7

2-(Difluoromethyl)-8,8-dimethyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one

CAS 2059940-67-7C₁₁H₁₄F₂N₂O