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Murcko scaffold

Ring system with 2 rings and 19 atoms

510 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
510
With full pages
255
Scaffold SMILES

O=C(COc1ccccc1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 510 chemicals

2-(2-Chlorophenoxy)-N'-(4-(dimethylamino)benzylidene)acetohydrazide chemical structure, C17H18ClN3O2, CAS 461708-68-9
2-(2-Chlorophenoxy)-N'-(4-(dimethylamino)benzylidene)acetohydrazide
CAS 461708-68-9C17H18ClN3O2
2-(2-Chlorophenoxy)-N'-(3,4-dimethoxybenzylidene)acetohydrazide chemical structure, C17H17ClN2O4, CAS 393114-86-8
2-(2-Chlorophenoxy)-N'-(3,4-dimethoxybenzylidene)acetohydrazide
CAS 393114-86-8C17H17ClN2O4
N'-Benzylidene-2-(2-chlorophenoxy)acetohydrazide chemical structure, C15H13ClN2O2, CAS 443977-32-0
N'-Benzylidene-2-(2-chlorophenoxy)acetohydrazide
CAS 443977-32-0C15H13ClN2O2
2-(2-Chlorophenoxy)-N'-(4-methylbenzylidene)acetohydrazide chemical structure, C16H15ClN2O2, CAS 409348-99-8
2-(2-Chlorophenoxy)-N'-(4-methylbenzylidene)acetohydrazide
CAS 409348-99-8C16H15ClN2O2
N'-(3-Chlorobenzylidene)-2-(2-chlorophenoxy)acetohydrazide chemical structure, C15H12Cl2N2O2, CAS 463974-19-8
N'-(3-Chlorobenzylidene)-2-(2-chlorophenoxy)acetohydrazide
CAS 463974-19-8C15H12Cl2N2O2
N'-(2-Chlorobenzylidene)-2-(2-chlorophenoxy)acetohydrazide chemical structure, C15H12Cl2N2O2, CAS 409349-50-4
N'-(2-Chlorobenzylidene)-2-(2-chlorophenoxy)acetohydrazide
CAS 409349-50-4C15H12Cl2N2O2
2-(4-Bromophenoxy)-N'-(4-methylbenzylidene)acetohydrazide chemical structure, C16H15BrN2O2, CAS 303066-18-4
2-(4-Bromophenoxy)-N'-(4-methylbenzylidene)acetohydrazide
CAS 303066-18-4C16H15BrN2O2
N'-(4-Methylbenzylidene)-2-(3-methylphenoxy)acetohydrazide chemical structure, C17H18N2O2, CAS 303065-52-3
N'-(4-Methylbenzylidene)-2-(3-methylphenoxy)acetohydrazide
CAS 303065-52-3C17H18N2O2
N'-[(1E)-1-(3-Aminophenyl)ethylidene]-2-(4-methoxyphenoxy)acetohydrazide chemical structure, C17H19N3O3, CAS 511515-70-1
N'-[(1E)-1-(3-Aminophenyl)ethylidene]-2-(4-methoxyphenoxy)acetohydrazide
CAS 511515-70-1C17H19N3O3
N'-(2-Ethoxybenzylidene)-2-(4-nitrophenoxy)acetohydrazide chemical structure, C17H17N3O5, CAS 303085-76-9
N'-(2-Ethoxybenzylidene)-2-(4-nitrophenoxy)acetohydrazide
CAS 303085-76-9C17H17N3O5
N'-(2,4-Dichlorobenzylidene)-2-(4-ethylphenoxy)acetohydrazide chemical structure, C17H16Cl2N2O2, CAS 301159-24-0
N'-(2,4-Dichlorobenzylidene)-2-(4-ethylphenoxy)acetohydrazide
CAS 301159-24-0C17H16Cl2N2O2
2-(2,4-Dichlorophenoxy)-N'-(2,3-dimethoxybenzylidene)acetohydrazide chemical structure, C17H16Cl2N2O4, CAS 339247-83-5
2-(2,4-Dichlorophenoxy)-N'-(2,3-dimethoxybenzylidene)acetohydrazide
CAS 339247-83-5C17H16Cl2N2O4
N'-(4-Bromobenzylidene)-2-(2,4-dichlorophenoxy)acetohydrazide chemical structure, C15H11BrCl2N2O2, CAS 324046-56-2
N'-(4-Bromobenzylidene)-2-(2,4-dichlorophenoxy)acetohydrazide
CAS 324046-56-2C15H11BrCl2N2O2
2-(2,4-Dichlorophenoxy)-N'-(2-methoxybenzylidene)acetohydrazide chemical structure, C16H14Cl2N2O3, CAS 303085-71-4
2-(2,4-Dichlorophenoxy)-N'-(2-methoxybenzylidene)acetohydrazide
CAS 303085-71-4C16H14Cl2N2O3
2-(2-Chlorophenoxy)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide chemical structure, C18H19ClN2O5, CAS 331452-62-1
2-(2-Chlorophenoxy)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide
CAS 331452-62-1C18H19ClN2O5
N'-[(E)-(4-Methylphenyl)methylidene]-2-[4-(trifluoromethyl)phenoxy]acetohydrazide chemical structure, C17H15F3N2O2, CAS 860649-72-5
N'-[(E)-(4-Methylphenyl)methylidene]-2-[4-(trifluoromethyl)phenoxy]acetohydrazide
CAS 860649-72-5C17H15F3N2O2
N'-(4-Methylbenzylidene)-2-(2-methylphenoxy)acetohydrazide chemical structure, C17H18N2O2, CAS 303087-37-8
N'-(4-Methylbenzylidene)-2-(2-methylphenoxy)acetohydrazide
CAS 303087-37-8C17H18N2O2
2-(4-Chlorophenoxy)-N'-(4-methylbenzylidene)acetohydrazide chemical structure, C16H15ClN2O2, CAS 106825-36-9
2-(4-Chlorophenoxy)-N'-(4-methylbenzylidene)acetohydrazide
CAS 106825-36-9C16H15ClN2O2
2-(2,4-Dichlorophenoxy)-N'-(4-methylbenzylidene)acetohydrazide chemical structure, C16H14Cl2N2O2, CAS 51496-68-5
2-(2,4-Dichlorophenoxy)-N'-(4-methylbenzylidene)acetohydrazide
CAS 51496-68-5C16H14Cl2N2O2
(E)-2-(4-Chloro-2-methylphenoxy)-N'-(4-methylbenzylidene)acetohydrazide chemical structure, C17H17ClN2O2, CAS 51496-77-6
(E)-2-(4-Chloro-2-methylphenoxy)-N'-(4-methylbenzylidene)acetohydrazide
CAS 51496-77-6C17H17ClN2O2
N'-(4-Isopropylbenzylidene)-2-phenoxyacetohydrazide chemical structure, C18H20N2O2, CAS 330672-03-2
N'-(4-Isopropylbenzylidene)-2-phenoxyacetohydrazide
CAS 330672-03-2C18H20N2O2
N-(3-{N-[(2,5-dichlorophenoxy)acetyl]ethanehydrazonoyl}phenyl)acetamide chemical structure, C18H17Cl2N3O3, CAS 445004-06-8
N-(3-{N-[(2,5-dichlorophenoxy)acetyl]ethanehydrazonoyl}phenyl)acetamide
CAS 445004-06-8C18H17Cl2N3O3
2-(4-Bromophenoxy)-N'-(4-nitrobenzylidene)acetohydrazide chemical structure, C15H12BrN3O4, CAS 303064-85-9
2-(4-Bromophenoxy)-N'-(4-nitrobenzylidene)acetohydrazide
CAS 303064-85-9C15H12BrN3O4
2-(2,4-Dichlorophenoxy)-N'-(3-methoxybenzylidene)acetohydrazide chemical structure, C16H14Cl2N2O3, CAS 302908-77-6
2-(2,4-Dichlorophenoxy)-N'-(3-methoxybenzylidene)acetohydrazide
CAS 302908-77-6C16H14Cl2N2O3