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Murcko scaffold

Ring system with 3 rings and 16 atoms

52 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 52
With full pages: 4

Scaffold SMILES

O=c1oc2ccccc2cc1-c1cscn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1oc2ccccc2cc1-c1cscn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

2-[4-(2-Oxochromen-3-yl)-1,3-thiazol-2-yl]acetonitrile chemical structure, C14H8N2O2S, CAS 88735-45-9

2-[4-(2-Oxochromen-3-yl)-1,3-thiazol-2-yl]acetonitrile

CAS 88735-45-9C₁₄H₈N₂O₂S

3-(2-Methyl-1,3-thiazol-4-yl)-2H-chromen-2-one chemical structure, C13H9NO2S, CAS 106578-02-3

3-(2-Methyl-1,3-thiazol-4-yl)-2H-chromen-2-one

CAS 106578-02-3C₁₃H₉NO₂S

3-(2-Methyl-1,3-thiazol-4-yl)-6-nitro-2H-chromen-2-one chemical structure, C13H8N2O4S, CAS 313497-22-2

3-(2-Methyl-1,3-thiazol-4-yl)-6-nitro-2H-chromen-2-one

CAS 313497-22-2C₁₃H₈N₂O₄S

3-(2-Aminothiazol-4-yl)-2H-chromen-2-one chemical structure, C12H8N2O2S, CAS 61636-28-0

3-(2-Aminothiazol-4-yl)-2H-chromen-2-one

CAS 61636-28-0C₁₂H₈N₂O₂S

Ethyl 2-[4-(2-oxochromen-3-yl)-1,3-thiazol-2-yl]acetate chemical structure, C16H13NO4S, CAS 442659-72-5

Ethyl 2-[4-(2-oxochromen-3-yl)-1,3-thiazol-2-yl]acetate

CAS 442659-72-5C₁₆H₁₃NO₄S

3-{2-[2-(Propan-2-ylidene)hydrazinyl]-1,3-thiazol-4-yl}-2H-chromen-2-one chemical structure, C15H13N3O2S, CAS 256511-34-9

3-{2-[2-(Propan-2-ylidene)hydrazinyl]-1,3-thiazol-4-yl}-2H-chromen-2-one

CAS 256511-34-9C₁₅H₁₃N₃O₂S

N-(4-(2-Oxo-2H-chromen-3-yl)thiazol-2-yl)pivalamide chemical structure, C17H16N2O3S, CAS 329903-13-1

N-(4-(2-Oxo-2H-chromen-3-yl)thiazol-2-yl)pivalamide

CAS 329903-13-1C₁₇H₁₆N₂O₃S

3-(2-Amino-1,3-thiazol-4-yl)-6,8-dichloro-2H-chromen-2-one chemical structure, C12H6Cl2N2O2S, CAS 176788-73-1

3-(2-Amino-1,3-thiazol-4-yl)-6,8-dichloro-2H-chromen-2-one

CAS 176788-73-1C₁₂H₆Cl₂N₂O₂S

6-Bromo-3-(2-methyl-1,3-thiazol-4-yl)chromen-2-one chemical structure, C13H8BrNO2S, CAS 106578-06-7

6-Bromo-3-(2-methyl-1,3-thiazol-4-yl)chromen-2-one

CAS 106578-06-7C₁₃H₈BrNO₂S

N-[4-(2-Oxochromen-3-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C14H10N2O3S, CAS 87503-73-9

N-[4-(2-Oxochromen-3-yl)-1,3-thiazol-2-yl]acetamide

CAS 87503-73-9C₁₄H₁₀N₂O₃S

N-[4-(8-Methoxy-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C15H12N2O4S, CAS 176788-80-0

N-[4-(8-Methoxy-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide

CAS 176788-80-0C₁₅H₁₂N₂O₄S

N-[4-(6-Nitro-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C14H9N3O5S, CAS 313233-63-5

N-[4-(6-Nitro-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide

CAS 313233-63-5C₁₄H₉N₃O₅S

8-Methoxy-3-(2-methyl-1,3-thiazol-4-yl)-2H-chromen-2-one chemical structure, C14H11NO3S, CAS 106578-03-4

8-Methoxy-3-(2-methyl-1,3-thiazol-4-yl)-2H-chromen-2-one

CAS 106578-03-4C₁₄H₁₁NO₃S

4-Oxo-4-((4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl)amino)butanoic acid chemical structure, C16H12N2O5S, CAS 422272-44-4

4-Oxo-4-((4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl)amino)butanoic acid

CAS 422272-44-4C₁₆H₁₂N₂O₅S

N-[4-(6-Methoxy-2-oxochromen-3-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C15H12N2O4S, CAS 324525-64-6

N-[4-(6-Methoxy-2-oxochromen-3-yl)-1,3-thiazol-2-yl]acetamide

CAS 324525-64-6C₁₅H₁₂N₂O₄S

2H-1-Benzopyran-2-one, 3-(2-amino-4-thiazolyl)-6-methoxy- chemical structure, C13H10N2O3S, CAS 313954-60-8

2H-1-Benzopyran-2-one, 3-(2-amino-4-thiazolyl)-6-methoxy-

CAS 313954-60-8C₁₃H₁₀N₂O₃S

N-(4-(2-Oxo-2H-chromen-3-yl)thiazol-2-yl)propionamide chemical structure, C15H12N2O3S, CAS 392249-24-0

N-(4-(2-Oxo-2H-chromen-3-yl)thiazol-2-yl)propionamide

CAS 392249-24-0C₁₅H₁₂N₂O₃S

2H-1-Benzopyran-2-one, 3-(2-amino-4-thiazolyl)-6,8-dibromo- chemical structure, C12H6Br2N2O2S, CAS 126357-22-0

2H-1-Benzopyran-2-one, 3-(2-amino-4-thiazolyl)-6,8-dibromo-

CAS 126357-22-0C₁₂H₆Br₂N₂O₂S

N-[4-(6-Bromo-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C14H9BrN2O3S, CAS 313956-42-2

N-[4-(6-Bromo-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide

CAS 313956-42-2C₁₄H₉BrN₂O₃S

N-[4-(6,8-Dichloro-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C14H8Cl2N2O3S, CAS 176788-84-4

N-[4-(6,8-Dichloro-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]acetamide

CAS 176788-84-4C₁₄H₈Cl₂N₂O₃S

3-(2-Amino-1,3-thiazol-4-yl)-6-bromo-2H-chromen-2-one chemical structure, C12H7BrN2O2S, CAS 126357-21-9

3-(2-Amino-1,3-thiazol-4-yl)-6-bromo-2H-chromen-2-one

CAS 126357-21-9C₁₂H₇BrN₂O₂S

3-(2-Amino-1,3-thiazol-4-yl)-7-propoxy-2H-chromen-2-one chemical structure, C15H14N2O3S, CAS 554407-09-9

3-(2-Amino-1,3-thiazol-4-yl)-7-propoxy-2H-chromen-2-one

CAS 554407-09-9C₁₅H₁₄N₂O₃S

3-(2-Amino-5-methyl-thiazol-4-yl)-chromen-2-one chemical structure, C13H10N2O2S, CAS 422272-41-1

3-(2-Amino-5-methyl-thiazol-4-yl)-chromen-2-one

CAS 422272-41-1C₁₃H₁₀N₂O₂S

3-(2-Amino-1,3-thiazol-4-yl)-7-methoxy-2H-chromen-2-one chemical structure, C13H10N2O3S, CAS 313954-61-9

3-(2-Amino-1,3-thiazol-4-yl)-7-methoxy-2H-chromen-2-one

CAS 313954-61-9C₁₃H₁₀N₂O₃S