Murcko scaffold
5,12-Naphthacenedione scaffold
79 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 20
- Chemicals
- 79
- With full pages
- 11
Scaffold SMILES
O=C1c2ccccc2C(=O)c2cc3ccccc3cc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 79 of 79 chemicals
6,11-Dihydroxy-2-methyltetracene-5,12-dione
CAS 88101-03-5C19H12O4
5,12-Dioxo-5,12-dihydrotetracene-2-carbaldehyde
CAS 144453-51-0C19H10O3
2,3,6,8,9,11-Hexachlorotetracene-5,12-dione
CAS 137313-63-4C18H4Cl6O2
2-Fluorotetracene-5,12-dione
CAS 91786-17-3C18H9FO2
7-Methyltetracene-5,12-dione
CAS 697799-55-6C19H12O2
2-Chlorotetracene-5,12-dione
CAS 85600-52-8C18H9ClO2
Bisanhydro-gamma-rhodomycinone
CAS 5236-40-8C20H14O5
7,8,9,10-Dehydro doxorubicinone
CAS 1159977-23-7C21H14O8
1,3,6,11-Tetrahydroxy-10-methoxytetracene-5,12-dione
CAS 1159977-24-8C19H12O7
Methyl 5,7,10-trihydroxy-2-methyl-6,11-dioxo-6,11-dihydrotetracene-1-carboxylate
CAS 19383-86-9C21H14O7
8-Bromotetracene-5,12-dione
CAS 126963-18-6C18H9BrO2
6-Chloro-1,11-dihydroxytetracene-5,12-dione
CAS 89564-21-6C18H9ClO4
12-Chloro-10-hydroxy-6,11-dioxo-6,11-dihydrotetracen-5-yl acetate
CAS 89564-48-7C20H11ClO5
12-Chloro-7-hydroxy-6,11-dioxo-6,11-dihydrotetracen-5-yl acetate
CAS 89564-49-8C20H11ClO5
11-Chloro-1-hydroxy-6-methoxytetracene-5,12-dione
CAS 89564-50-1C19H11ClO4
6-Chloro-1-hydroxy-11-methoxytetracene-5,12-dione
CAS 89564-51-2C19H11ClO4
11-Chloro-1,6-dihydroxytetracene-5,12-dione
CAS 89564-52-3C18H9ClO4
3-Ethyl-1,6,10,11-tetrahydroxytetracene-5,12-dione
CAS 93240-54-1C20H14O6
1,7,11-Trihydroxytetracene-5,12-dione
CAS 94620-40-3C18H10O5
5,12-Naphthacenedione, 6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-
CAS 105612-58-6C21H14O7
6-(Dimethylamino)tetracene-5,12-dione
CAS 193604-00-1C20H15NO2
1-Amino-7,10-dibromo-4-hydroxy-2-methoxytetracene-5,12-dione
CAS 63339-77-5C19H11Br2NO4
1-Amino-4-hydroxy-2-methoxytetracene-5,12-dione
CAS 63339-76-4C19H13NO4
8-Ethyl-6,11-bis(hydroxymethoxy)tetracene-5,12-dione
CAS 62242-57-3C22H18O6
- 2-Ethyl-6,11-dihydroxytetracene-5,12-dione88101-06-8C20H14O4
- 1,6,11-Trihydroxy-2-methyltetracene-5,12-dione88101-02-4C19H12O5
- 11-Chloro-2,6-dihydroxytetracene-5,12-dione83352-52-7C18H9ClO4
- 6,11-Bis[(trimethylsilyl)oxy]tetracene-5,12-dione919782-49-3C24H26O4Si2
- eta-Isorhodomycinone477-53-2C22H16O8
- Methyl Bis-anhydro-Daunomycinone Carboxylate71809-95-5C21H14O7
- 8-Acetyl-1,6,11-trihydroxytetracene-5,12-dione78901-92-5C20H12O6
Related scaffolds
Same ring framework with different atoms or bond orders
O=C1C=CC2C(=O)C3=Cc4ccccc4CC3CC2C163 chemicals
O=c1c2ccccc2oc2cc3c(cc12)C=CCO314 chemicals
O=C1c2ccccc2C(=O)c2cc3c(cc21)CCCC313 chemicals
O=C1C=CC2C(=O)c3cc4ccccc4cc3CC2C16 chemicals
O=c1c2ccccc2oc2cc3c(cc12)CCCO34 chemicals
O=c1c2ccccc2oc2nc3n(c(=O)c12)CCCS33 chemicals
O=C1c2cc3ccccc3cc2C(=O)C2C(=O)C=CCC123 chemicals
C=C1c2ccccc2C=C2C(=O)C3C=CC(=O)CC3CC123 chemicals
O=C1CCCc2cc3c(cc21)C(=O)c1ccccc1C3=O2 chemicals![Scaffold O=c1[nH]cnc2c1NC1CC3O[PH](=O)OCC3OC1N2](/scaffold/JGCXBWNZYNTBBR-UHFFFAOYSA-N/structure.svg)
O=c1[nH]cnc2c1NC1CC3O[PH](=O)OCC3OC1N22 chemicals
O=C1c2ccccc2C(=O)c2cc3c(=O)ccoc3cc212 chemicals
c1cnc2c(c1)Nc1nc3ccccc3nc1S21 chemical