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Murcko scaffold

Ring system with 4 rings and 24 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
7
With full pages
1
Scaffold SMILES

O=C(Nc1ccccc1)c1cc2ccc(-c3cccnc3)nc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cc2ccc(-c3cccnc3)nc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

3-Amino-N-phenyl-6-pyridin-3-ylthieno[2,3-b]pyridine-2-carboxamide chemical structure, C19H14N4OS, CAS 340817-11-0
3-Amino-N-phenyl-6-pyridin-3-ylthieno[2,3-b]pyridine-2-carboxamide
CAS 340817-11-0C19H14N4OS
3-Amino-N-(2,6-dichlorophenyl)-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide chemical structure, C19H12Cl2N4OS, CAS 625370-72-1
3-Amino-N-(2,6-dichlorophenyl)-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide
CAS 625370-72-1C19H12Cl2N4OS
SOD1-Derlin-1 inhibitor-1 chemical structure, C19H12Br2N4OS, CAS 840461-03-2
SOD1-Derlin-1 inhibitor-1
CAS 840461-03-2C19H12Br2N4OS
3-Amino-N-(2-fluorophenyl)-6-(3-pyridinyl)-2-thieno[2,3-b]pyridinecarboxamide chemical structure, C19H13FN4OS, CAS 498569-24-7
3-Amino-N-(2-fluorophenyl)-6-(3-pyridinyl)-2-thieno[2,3-b]pyridinecarboxamide
CAS 498569-24-7C19H13FN4OS
3-Amino-N-(2,4-dichlorophenyl)-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide chemical structure, C19H12Cl2N4OS, CAS 489402-79-1
3-Amino-N-(2,4-dichlorophenyl)-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide
CAS 489402-79-1C19H12Cl2N4OS
3-Amino-N-(2-chloro-5-methoxyphenyl)-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide chemical structure, C20H15ClN4O2S, CAS 878977-43-6
3-Amino-N-(2-chloro-5-methoxyphenyl)-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide
CAS 878977-43-6C20H15ClN4O2S
SOD1-Derlin-1 inhibitor-2 chemical structure, C22H18N4OS, CAS 2170170-27-9
SOD1-Derlin-1 inhibitor-2
CAS 2170170-27-9C22H18N4OS