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Murcko scaffold

Ring system with 3 rings and 20 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
20
With full pages
15
Scaffold SMILES

c1ccc(Nc2ncnc(CN3CCCCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ncnc(CN3CCCCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

1-({4-Amino-6-[(2,3-dimethylphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide chemical structure, C18H25N7O, CAS 575460-21-8
1-({4-Amino-6-[(2,3-dimethylphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide
CAS 575460-21-8C18H25N7O
N-(2,4-Dimethylphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine chemical structure, C18H26N6, CAS 433695-31-9
N-(2,4-Dimethylphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine
CAS 433695-31-9C18H26N6
N2-(4-methoxyphenyl)-6-(1-piperidinylmethyl)-1,3,5-triazine-2,4-diamine chemical structure, C16H22N6O, CAS 433694-46-3
N2-(4-methoxyphenyl)-6-(1-piperidinylmethyl)-1,3,5-triazine-2,4-diamine
CAS 433694-46-3C16H22N6O
N-(3-Chloro-2-methylphenyl)-6-(piperidin-1-ylmethyl)-1,3,5-triazine-2,4-diamine chemical structure, C16H21ClN6, CAS 448914-84-9
N-(3-Chloro-2-methylphenyl)-6-(piperidin-1-ylmethyl)-1,3,5-triazine-2,4-diamine
CAS 448914-84-9C16H21ClN6
N-(2,3-Dimethylphenyl)-6-[(4-methyl-1-piperidinyl)methyl]-1,3,5-triazine-2,4-diamine chemical structure, C18H26N6, CAS 524056-71-1
N-(2,3-Dimethylphenyl)-6-[(4-methyl-1-piperidinyl)methyl]-1,3,5-triazine-2,4-diamine
CAS 524056-71-1C18H26N6
N-(2-Methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine chemical structure, C17H24N6O, CAS 669743-81-1
N-(2-Methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine
CAS 669743-81-1C17H24N6O
N-(4-Methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine chemical structure, C17H24N6O, CAS 669743-06-0
N-(4-Methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine
CAS 669743-06-0C17H24N6O
1-({(6Z)-4-Amino-6-[(4-methoxyphenyl)imino]-1,6-dihydro-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide chemical structure, C17H23N7O2, CAS 669743-31-1
1-({(6Z)-4-Amino-6-[(4-methoxyphenyl)imino]-1,6-dihydro-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide
CAS 669743-31-1C17H23N7O2
1-({4-Amino-6-[(2-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide chemical structure, C17H23N7O2, CAS 669743-95-7
1-({4-Amino-6-[(2-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide
CAS 669743-95-7C17H23N7O2
Ethyl 1-[(4-amino-6-anilino-1,3,5-triazin-2-yl)methyl]-3-piperidinecarboxylate chemical structure, C18H24N6O2, CAS 585551-79-7
Ethyl 1-[(4-amino-6-anilino-1,3,5-triazin-2-yl)methyl]-3-piperidinecarboxylate
CAS 585551-79-7C18H24N6O2
Ethyl 1-({4-amino-6-[(4-methylphenyl)amino]-1,3,5-triazin-2-yl}methyl)-3-piperidinecarboxylate chemical structure, C19H26N6O2, CAS 700857-77-8
Ethyl 1-({4-amino-6-[(4-methylphenyl)amino]-1,3,5-triazin-2-yl}methyl)-3-piperidinecarboxylate
CAS 700857-77-8C19H26N6O2
6-(3,5-Dimethyl-piperidin-1-ylmethyl)-N-phenyl-[1,3,5]triazine-2,4-diamine chemical structure, C17H24N6, CAS 700859-27-4
6-(3,5-Dimethyl-piperidin-1-ylmethyl)-N-phenyl-[1,3,5]triazine-2,4-diamine
CAS 700859-27-4C17H24N6
N-(2-Ethoxyphenyl)-6-[(2-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine chemical structure, C18H26N6O, CAS 674305-63-6
N-(2-Ethoxyphenyl)-6-[(2-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine
CAS 674305-63-6C18H26N6O
6-[(3,5-Dimethylpiperidin-1-yl)methyl]-N-(4-ethoxyphenyl)-1,3,5-triazine-2,4-diamine chemical structure, C19H28N6O, CAS 670240-50-3
6-[(3,5-Dimethylpiperidin-1-yl)methyl]-N-(4-ethoxyphenyl)-1,3,5-triazine-2,4-diamine
CAS 670240-50-3C19H28N6O
Ethyl 1-({4-amino-6-[(2-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-3-carboxylate chemical structure, C19H26N6O3, CAS 669744-01-8
Ethyl 1-({4-amino-6-[(2-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-3-carboxylate
CAS 669744-01-8C19H26N6O3
Ethyl 1-({4-amino-6-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl)-3-piperidinecarboxylate chemical structure, C19H26N6O3, CAS 669743-55-9
Ethyl 1-({4-amino-6-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl)-3-piperidinecarboxylate
CAS 669743-55-9C19H26N6O3
6-[(3,5-Dimethylpiperidin-1-yl)methyl]-N-(2-methoxyphenyl)-1,3,5-triazine-2,4-diamine chemical structure, C18H26N6O, CAS 669743-84-4
6-[(3,5-Dimethylpiperidin-1-yl)methyl]-N-(2-methoxyphenyl)-1,3,5-triazine-2,4-diamine
CAS 669743-84-4C18H26N6O
N-(3-Chloro-2-methylphenyl)-6-[(2-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine chemical structure, C17H23ClN6, CAS 488708-50-5
N-(3-Chloro-2-methylphenyl)-6-[(2-methylpiperidin-1-yl)methyl]-1,3,5-triazine-2,4-diamine
CAS 488708-50-5C17H23ClN6
1-({4-Amino-6-[(4-methylphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide chemical structure, C17H23N7O, CAS 522660-39-5
1-({4-Amino-6-[(4-methylphenyl)amino]-1,3,5-triazin-2-yl}methyl)piperidine-4-carboxamide
CAS 522660-39-5C17H23N7O
1-{[4-Amino-6-(3-methoxyanilino)-1,3,5-triazin-2-yl]methyl}-4-piperidinecarboxamide chemical structure, C17H23N7O2, CAS 895359-74-7
1-{[4-Amino-6-(3-methoxyanilino)-1,3,5-triazin-2-yl]methyl}-4-piperidinecarboxamide
CAS 895359-74-7C17H23N7O2