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Murcko scaffold

Ring system with 3 rings and 23 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
12
With full pages
7
Scaffold SMILES

O=C(C1CCCN(S(=O)(=O)c2ccccc2)C1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C1CCCN(S(=O)(=O)c2ccccc2)C1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

[1-(4-Chlorophenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone chemical structure, C17H24ClN3O3S, CAS 524060-59-1
[1-(4-Chlorophenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone
CAS 524060-59-1C17H24ClN3O3S
[1-(4-Methoxyphenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone chemical structure, C18H27N3O4S, CAS 524675-44-3
[1-(4-Methoxyphenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone
CAS 524675-44-3C18H27N3O4S
(4-Methylpiperazin-1-yl)-[1-(4-nitrophenyl)sulfonylpiperidin-3-yl]methanone chemical structure, C17H24N4O5S, CAS 524675-51-2
(4-Methylpiperazin-1-yl)-[1-(4-nitrophenyl)sulfonylpiperidin-3-yl]methanone
CAS 524675-51-2C17H24N4O5S
(4-Methylpiperazin-1-yl)-[1-(2-nitrophenyl)sulfonylpiperidin-3-yl]methanone chemical structure, C17H24N4O5S, CAS 524675-57-8
(4-Methylpiperazin-1-yl)-[1-(2-nitrophenyl)sulfonylpiperidin-3-yl]methanone
CAS 524675-57-8C17H24N4O5S
Ethyl 4-[1-(4-fluorophenyl)sulfonylpiperidine-3-carbonyl]piperazine-1-carboxylate chemical structure, C19H26FN3O5S, CAS 717892-17-6
Ethyl 4-[1-(4-fluorophenyl)sulfonylpiperidine-3-carbonyl]piperazine-1-carboxylate
CAS 717892-17-6C19H26FN3O5S
1-(Benzenesulfonyl)-N-[4-chloro-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide chemical structure, C19H27N3O5S, CAS 830351-78-5
1-(Benzenesulfonyl)-N-[4-chloro-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide
CAS 830351-78-5C19H27N3O5S
[1-(4-Fluorophenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone chemical structure, C17H24FN3O3S, CAS 524060-40-0
[1-(4-Fluorophenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone
CAS 524060-40-0C17H24FN3O3S
(4-Methylpiperazin-1-yl)[1-(phenylsulfonyl)piperidin-3-yl]methanone chemical structure, C17H25N3O3S, CAS 524060-48-8
(4-Methylpiperazin-1-yl)[1-(phenylsulfonyl)piperidin-3-yl]methanone
CAS 524060-48-8C17H25N3O3S
[1-(4-Methylphenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone chemical structure, C18H27N3O3S, CAS 524060-54-6
[1-(4-Methylphenyl)sulfonylpiperidin-3-yl]-(4-methylpiperazin-1-yl)methanone
CAS 524060-54-6C18H27N3O3S
1-[1-(4-Nitrobenzenesulfonyl)piperidine-3-carbonyl]piperazine chemical structure, C16H22N4O5S, CAS 1837507-75-1
1-[1-(4-Nitrobenzenesulfonyl)piperidine-3-carbonyl]piperazine
CAS 1837507-75-1C16H22N4O5S
1-[1-(Benzenesulfonyl)piperidine-3-carbonyl]-4-(prop-2-yn-1-yl)piperazine chemical structure, C19H25N3O3S, CAS 2094334-65-1
1-[1-(Benzenesulfonyl)piperidine-3-carbonyl]-4-(prop-2-yn-1-yl)piperazine
CAS 2094334-65-1C19H25N3O3S
1-[1-(2-Nitrobenzenesulfonyl)piperidine-3-carbonyl]piperazine chemical structure, C16H22N4O5S, CAS 2138567-45-8
1-[1-(2-Nitrobenzenesulfonyl)piperidine-3-carbonyl]piperazine
CAS 2138567-45-8C16H22N4O5S