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Murcko scaffold

2-N,4-N-diphenylpyrimidine-2,4-diamine scaffold

149 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
149
With full pages
17
Scaffold SMILES

c1ccc(Nc2ccnc(Nc3ccccc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-N,4-N-diphenylpyrimidine-2,4-diamine page
Murcko scaffold c1ccc(Nc2ccnc(Nc3ccccc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 149 chemicals

Anthranilic acid, N-(2-anilino-4-pyrimidinyl)- chemical structure, C17H14N4O2, CAS 89450-91-9
Anthranilic acid, N-(2-anilino-4-pyrimidinyl)-
CAS 89450-91-9C17H14N4O2
Dapivirine chemical structure, C20H19N5, CAS 244767-67-7
Dapivirine
CAS 244767-67-7C20H19N5
N~2~,N~4~-Bis(4-fluorophenyl)-6-methyl-5-nitropyrimidine-2,4-diamine chemical structure, C17H13F2N5O2, CAS 1525-17-3
N~2~,N~4~-Bis(4-fluorophenyl)-6-methyl-5-nitropyrimidine-2,4-diamine
CAS 1525-17-3C17H13F2N5O2
n2-(3,4-Dichlorophenyl)-n4-{3-[(diethylamino)methyl]-4-methoxyphenyl}-6-methylpyrimidine-2,4-diamine chemical structure, C23H27Cl2N5O, CAS 71523-79-0
n2-(3,4-Dichlorophenyl)-n4-{3-[(diethylamino)methyl]-4-methoxyphenyl}-6-methylpyrimidine-2,4-diamine
CAS 71523-79-0C23H27Cl2N5O
4-[(4-Cyano-2,6-dimethylphenyl)amino]-2-[(4-cyanophenyl)amino]pyrimidine-5-carbonitrile chemical structure, C21H15N7, CAS 269055-11-0
4-[(4-Cyano-2,6-dimethylphenyl)amino]-2-[(4-cyanophenyl)amino]pyrimidine-5-carbonitrile
CAS 269055-11-0C21H15N7
4-({4-[(4-Bromo-2,6-dimethylphenyl)amino]pyrimidin-2-yl}amino)benzonitrile chemical structure, C19H16BrN5, CAS 374067-85-3
4-({4-[(4-Bromo-2,6-dimethylphenyl)amino]pyrimidin-2-yl}amino)benzonitrile
CAS 374067-85-3C19H16BrN5
4-[[4-(2,6-Dimethylanilino)pyrimidin-2-yl]amino]benzonitrile chemical structure, C19H17N5, CAS 244768-59-0
4-[[4-(2,6-Dimethylanilino)pyrimidin-2-yl]amino]benzonitrile
CAS 244768-59-0C19H17N5
4-[[4-(4-Chloro-2,6-dimethyl-anilino)pyrimidin-2-yl]amino]benzonitrile chemical structure, C19H16ClN5, CAS 244767-93-9
4-[[4-(4-Chloro-2,6-dimethyl-anilino)pyrimidin-2-yl]amino]benzonitrile
CAS 244767-93-9C19H16ClN5
5-Fluoro-2-N,4-N-diphenylpyrimidine-2,4-diamine chemical structure, C16H13FN4, CAS 40423-75-4
5-Fluoro-2-N,4-N-diphenylpyrimidine-2,4-diamine
CAS 40423-75-4C16H13FN4
N2,N4-bis(2,4-dimethylphenyl)-6-methylpyrimidine-2,4-diamine chemical structure, C21H24N4, CAS 303193-02-4
N2,N4-bis(2,4-dimethylphenyl)-6-methylpyrimidine-2,4-diamine
CAS 303193-02-4C21H24N4
5-Fluoro-N,N'-bis(4-methoxyphenyl)pyrimidine-2,4-diamine chemical structure, C18H17FN4O2, CAS 312616-70-9
5-Fluoro-N,N'-bis(4-methoxyphenyl)pyrimidine-2,4-diamine
CAS 312616-70-9C18H17FN4O2
2-N,4-N-diphenylpyrimidine-2,4-diamine chemical structure, C16H14N4, CAS 28458-89-1
2-N,4-N-diphenylpyrimidine-2,4-diamine
CAS 28458-89-1C16H14N4
5-Fluoro-N,N'-bis(4-fluorophenyl)pyrimidine-2,4-diamine chemical structure, C16H11F3N4, CAS 40505-53-1
5-Fluoro-N,N'-bis(4-fluorophenyl)pyrimidine-2,4-diamine
CAS 40505-53-1C16H11F3N4
2,4-Pyrimidinediamine, N,N'-bis(2-chlorophenyl)-5-fluoro- chemical structure, C16H11Cl2FN4, CAS 312616-72-1
2,4-Pyrimidinediamine, N,N'-bis(2-chlorophenyl)-5-fluoro-
CAS 312616-72-1C16H11Cl2FN4
Diethyl 4,4'-[(6-methylpyrimidine-2,4-diyl)diimino]dibenzoate chemical structure, C23H24N4O4, CAS 51944-29-7
Diethyl 4,4'-[(6-methylpyrimidine-2,4-diyl)diimino]dibenzoate
CAS 51944-29-7C23H24N4O4
2-N,4-N-bis(4-methoxyphenyl)-6-methyl-5-nitropyrimidine-2,4-diamine chemical structure, C19H19N5O4, CAS 392696-58-1
2-N,4-N-bis(4-methoxyphenyl)-6-methyl-5-nitropyrimidine-2,4-diamine
CAS 392696-58-1C19H19N5O4
Anthranilic acid, N,N'-(5-bromo-6-methylpyrimidin-2,4-ylene)di-, hydrochloride chemical structure, C19H16BrClN4O4, CAS 89450-92-0
Anthranilic acid, N,N'-(5-bromo-6-methylpyrimidin-2,4-ylene)di-, hydrochloride
CAS 89450-92-0C19H16BrClN4O4
4-Pyrimidinecarboxylic acid, 2,6-bis(o-carboxyanilino)-, hydrochloride chemical structure, C19H15ClN4O6, CAS 89450-93-1
4-Pyrimidinecarboxylic acid, 2,6-bis(o-carboxyanilino)-, hydrochloride
CAS 89450-93-1C19H15ClN4O6
N4,6-Dimethyl-5-nitro-N2-(3-nitrophenyl)-N4-phenyl-2,4-pyrimidinediamine chemical structure, C18H16N6O4, CAS 330566-31-9
N4,6-Dimethyl-5-nitro-N2-(3-nitrophenyl)-N4-phenyl-2,4-pyrimidinediamine
CAS 330566-31-9C18H16N6O4
5-Nitro-2,4-bis(4-iodoanilino)-6-methylpyrimidine chemical structure, C17H13I2N5O2, CAS 331464-74-5
5-Nitro-2,4-bis(4-iodoanilino)-6-methylpyrimidine
CAS 331464-74-5C17H13I2N5O2
5-Nitro-4-methyl-2,6-di(2-toluidino)pyrimidine chemical structure, C19H19N5O2, CAS 312924-48-4
5-Nitro-4-methyl-2,6-di(2-toluidino)pyrimidine
CAS 312924-48-4C19H19N5O2
N2-(4-ethoxyphenyl)-N4-(2-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamine chemical structure, C19H20N6O4, CAS 673494-35-4
N2-(4-ethoxyphenyl)-N4-(2-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamine
CAS 673494-35-4C19H20N6O4
N4-(2-methoxyphenyl)-5-nitro-N2-phenylpyrimidine-2,4,6-triamine chemical structure, C17H16N6O3, CAS 673453-47-9
N4-(2-methoxyphenyl)-5-nitro-N2-phenylpyrimidine-2,4,6-triamine
CAS 673453-47-9C17H16N6O3
N2-(2-fluorophenyl)-N4-(4-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamine chemical structure, C17H15FN6O3, CAS 714917-94-9
N2-(2-fluorophenyl)-N4-(4-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamine
CAS 714917-94-9C17H15FN6O3