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Murcko scaffold

5-(Pyrrolidin-2-yl)isoxazole scaffold

39 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
39
With full pages
10
Scaffold SMILES

c1cc(C2CCCN2)on1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Pyrrolidin-2-yl)isoxazole page
Murcko scaffold c1cc(C2CCCN2)on1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole chemical structure, C9H14N2O, CAS 147402-53-7
3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole
CAS 147402-53-7C9H14N2O
(R)-3-Methyl-5-(1-methylpyrrolidin-2-yl)isoxazole chemical structure, C9H14N2O, CAS 147402-73-1
(R)-3-Methyl-5-(1-methylpyrrolidin-2-yl)isoxazole
CAS 147402-73-1C9H14N2O
(S)-3-Methyl-5-(pyrrolidin-2-yl)isoxazole chemical structure, C8H12N2O, CAS 147402-52-6
(S)-3-Methyl-5-(pyrrolidin-2-yl)isoxazole
CAS 147402-52-6C8H12N2O
(R)-3-Methyl-5-(pyrrolidin-2-yl)isoxazole chemical structure, C8H12N2O, CAS 147402-72-0
(R)-3-Methyl-5-(pyrrolidin-2-yl)isoxazole
CAS 147402-72-0C8H12N2O
(2S)-2-[3-Ethylisoxazol-5-yl]pyrrolidine chemical structure, C9H14N2O, CAS 147402-55-9
(2S)-2-[3-Ethylisoxazol-5-yl]pyrrolidine
CAS 147402-55-9C9H14N2O
(R)-3-Ethyl-5-(pyrrolidin-2-yl)isoxazole chemical structure, C9H14N2O, CAS 147402-75-3
(R)-3-Ethyl-5-(pyrrolidin-2-yl)isoxazole
CAS 147402-75-3C9H14N2O
ABT-418 hydrochloride chemical structure, C9H15ClN2O, CAS 147388-83-8
ABT-418 hydrochloride
CAS 147388-83-8C9H15ClN2O
3-Methyl-5-(pyrrolidin-2-yl)-1,2-oxazole chemical structure, C8H12N2O, CAS 851434-82-7
3-Methyl-5-(pyrrolidin-2-yl)-1,2-oxazole
CAS 851434-82-7C8H12N2O
3-Methyl-5-(1-methylpyrrolidin-2-yl)isoxazole chemical structure, C9H14N2O, CAS 243119-20-2
3-Methyl-5-(1-methylpyrrolidin-2-yl)isoxazole
CAS 243119-20-2C9H14N2O
3-Ethyl-5-pyrrolidin-2-ylisoxazole chemical structure, C9H14N2O, CAS 1018126-13-0
3-Ethyl-5-pyrrolidin-2-ylisoxazole
CAS 1018126-13-0C9H14N2O
tert-Butyl 2-(3-(trifluoromethyl)isoxazol-5-yl)pyrrolidine-1-carboxylate chemical structure, C13H17F3N2O3, CAS 1824514-40-0
tert-Butyl 2-(3-(trifluoromethyl)isoxazol-5-yl)pyrrolidine-1-carboxylate
CAS 1824514-40-0C13H17F3N2O3
5-(Pyrrolidin-2-yl)isoxazole chemical structure, C7H10N2O, CAS 164351-64-8
5-(Pyrrolidin-2-yl)isoxazole
CAS 164351-64-8C7H10N2O
tert-Butyl 2-(3-bromo-1,2-oxazol-5-yl)pyrrolidine-1-carboxylate chemical structure, C12H17BrN2O3, CAS 3017211-16-1
tert-Butyl 2-(3-bromo-1,2-oxazol-5-yl)pyrrolidine-1-carboxylate
CAS 3017211-16-1C12H17BrN2O3
5-(1-Methylpyrrolidin-2-yl)isoxazole chemical structure, C8H12N2O, CAS 164351-65-9
5-(1-Methylpyrrolidin-2-yl)isoxazole
CAS 164351-65-9C8H12N2O
3-Isopropyl-5-pyrrolidin-2-ylisoxazole chemical structure, C10H16N2O, CAS 1018163-28-4
3-Isopropyl-5-pyrrolidin-2-ylisoxazole
CAS 1018163-28-4C10H16N2O
(S)-5-(1-Methylpyrrolidin-2-yl)isoxazole chemical structure, C8H12N2O, CAS 472960-17-1
(S)-5-(1-Methylpyrrolidin-2-yl)isoxazole
CAS 472960-17-1C8H12N2O
1-[2-(3-Methyl-1,2-oxazol-5-yl)pyrrolidin-1-yl]prop-2-en-1-one chemical structure, C11H14N2O2, CAS 1183408-58-3
1-[2-(3-Methyl-1,2-oxazol-5-yl)pyrrolidin-1-yl]prop-2-en-1-one
CAS 1183408-58-3C11H14N2O2
5-Pyrrolidin-2-ylisoxazole dihydrochloride chemical structure, C7H12Cl2N2O, CAS 1993054-67-3
5-Pyrrolidin-2-ylisoxazole dihydrochloride
CAS 1993054-67-3C7H12Cl2N2O
1,1-Dimethylethyl (2S)-2-(5-isoxazolyl)-1-pyrrolidinecarboxylate chemical structure, C12H18N2O3, CAS 217805-60-2
1,1-Dimethylethyl (2S)-2-(5-isoxazolyl)-1-pyrrolidinecarboxylate
CAS 217805-60-2C12H18N2O3
Tcv6hje4ZN chemical structure, C9H14N2O2, CAS 158840-76-7
Tcv6hje4ZN
CAS 158840-76-7C9H14N2O2
ABT-418-N-oxide, S-cis- chemical structure, C9H14N2O2, CAS 158840-77-8
ABT-418-N-oxide, S-cis-
CAS 158840-77-8C9H14N2O2
tert-Butyl 2-(4-amino-1,2-oxazol-5-yl)pyrrolidine-1-carboxylate chemical structure, C12H19N3O3, CAS 1784583-48-7
tert-Butyl 2-(4-amino-1,2-oxazol-5-yl)pyrrolidine-1-carboxylate
CAS 1784583-48-7C12H19N3O3
5-{1-[(tert-Butoxy)carbonyl]pyrrolidin-2-yl}-1,2-oxazole-4-carboxylic acid chemical structure, C13H18N2O5, CAS 1784600-06-1
5-{1-[(tert-Butoxy)carbonyl]pyrrolidin-2-yl}-1,2-oxazole-4-carboxylic acid
CAS 1784600-06-1C13H18N2O5
5-{1-[(tert-Butoxy)carbonyl]pyrrolidin-2-yl}-1,2-oxazole-3-carboxylic acid chemical structure, C13H18N2O5, CAS 1824513-70-3
5-{1-[(tert-Butoxy)carbonyl]pyrrolidin-2-yl}-1,2-oxazole-3-carboxylic acid
CAS 1824513-70-3C13H18N2O5