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Murcko scaffold

N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenylacetamide scaffold

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(Cc1ccccc1)Nc1ccc2c(c1)C(=O)NC2=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenylacetamide page
Murcko scaffold O=C(Cc1ccccc1)Nc1ccc2c(c1)C(=O)NC2=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-(4-Chlorophenyl)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide chemical structure, C17H13ClN2O3, CAS 433242-34-3
2-(4-Chlorophenyl)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide
CAS 433242-34-3C17H13ClN2O3
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenylacetamide chemical structure, C16H12N2O3, CAS 404840-37-5
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenylacetamide
CAS 404840-37-5C16H12N2O3
N-(1,3-Dioxoisoindol-5-yl)-2-(4-nitrophenyl)acetamide chemical structure, C16H11N3O5, CAS 690989-32-3
N-(1,3-Dioxoisoindol-5-yl)-2-(4-nitrophenyl)acetamide
CAS 690989-32-3C16H11N3O5
2-(4-Chlorophenyl)-N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide chemical structure, C16H11ClN2O3, CAS 500262-82-8
2-(4-Chlorophenyl)-N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide
CAS 500262-82-8C16H11ClN2O3
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-(2-methoxyphenyl)acetamide chemical structure, C17H14N2O4, CAS 665025-61-6
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-(2-methoxyphenyl)acetamide
CAS 665025-61-6C17H14N2O4
2-(4-Fluorophenyl)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)acetamide chemical structure, C17H13FN2O3, CAS 922700-59-2
2-(4-Fluorophenyl)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)acetamide
CAS 922700-59-2C17H13FN2O3
N-(1,3-Dioxoisoindol-5-yl)-2-(4-ethoxyphenyl)acetamide chemical structure, C18H16N2O4, CAS 923371-99-7
N-(1,3-Dioxoisoindol-5-yl)-2-(4-ethoxyphenyl)acetamide
CAS 923371-99-7C18H16N2O4
N-(1,3-Dioxoisoindolin-5-yl)-2-(4-(methylthio)phenyl)acetamide chemical structure, C17H14N2O3S, CAS 919844-29-4
N-(1,3-Dioxoisoindolin-5-yl)-2-(4-(methylthio)phenyl)acetamide
CAS 919844-29-4C17H14N2O3S
N-(1,3-Dioxoisoindolin-5-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide chemical structure, C18H16N2O5S, CAS 919858-25-6
N-(1,3-Dioxoisoindolin-5-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide
CAS 919858-25-6C18H16N2O5S