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Murcko scaffold

Ring system with 2 rings and 18 atoms

106 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
106
With full pages
10
Scaffold SMILES

O=C(Cc1ccccc1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 106 chemicals

N'-[(Z)-1-(4-Aminophenyl)ethylidene]-2-(4-methoxyphenyl)acetohydrazide chemical structure, C17H19N3O2, CAS 346721-15-1
N'-[(Z)-1-(4-Aminophenyl)ethylidene]-2-(4-methoxyphenyl)acetohydrazide
CAS 346721-15-1C17H19N3O2
I+/--Hydroxybenzeneacetic acid 2-[(2-chloro-6-fluorophenyl)methylene]hydrazide chemical structure, C15H12ClFN2O2, CAS 550299-60-0
I+/--Hydroxybenzeneacetic acid 2-[(2-chloro-6-fluorophenyl)methylene]hydrazide
CAS 550299-60-0C15H12ClFN2O2
4-Methoxybenzeneacetic acid 2-[(3,4-dichlorophenyl)methylene]hydrazide chemical structure, C16H14Cl2N2O2, CAS 544681-98-3
4-Methoxybenzeneacetic acid 2-[(3,4-dichlorophenyl)methylene]hydrazide
CAS 544681-98-3C16H14Cl2N2O2
N'-(1-(4-Bromophenyl)-4,4,4-trifluoro-3-oxobutylidene)-2-phenylacetohydrazide chemical structure, C18H14BrF3N2O2, CAS 672900-33-3
N'-(1-(4-Bromophenyl)-4,4,4-trifluoro-3-oxobutylidene)-2-phenylacetohydrazide
CAS 672900-33-3C18H14BrF3N2O2
N'-(3-Bromobenzylidene)-2-(3-(trifluoromethyl)phenyl)acetohydrazide chemical structure, C16H12BrF3N2O, CAS 359604-56-1
N'-(3-Bromobenzylidene)-2-(3-(trifluoromethyl)phenyl)acetohydrazide
CAS 359604-56-1C16H12BrF3N2O
N-[(3,5-Dibromo-2-hydroxyphenyl)methylideneamino]-2-hydroxy-2-phenylacetamide chemical structure, C15H12Br2N2O3
N-[(3,5-Dibromo-2-hydroxyphenyl)methylideneamino]-2-hydroxy-2-phenylacetamide
C15H12Br2N2O3
N-[1-(3,4-Dichlorophenyl)ethylideneamino]-2-(4-nitrophenyl)acetamide chemical structure, C16H13Cl2N3O3, CAS 6387-91-3
N-[1-(3,4-Dichlorophenyl)ethylideneamino]-2-(4-nitrophenyl)acetamide
CAS 6387-91-3C16H13Cl2N3O3
N'-(2-Chlorobenzylidene)-2-phenylacetohydrazide chemical structure, C15H13ClN2O, CAS 93476-65-4
N'-(2-Chlorobenzylidene)-2-phenylacetohydrazide
CAS 93476-65-4C15H13ClN2O
N'-(3-Chlorobenzylidene)-2-phenylacetohydrazide chemical structure, C15H13ClN2O, CAS 94090-75-2
N'-(3-Chlorobenzylidene)-2-phenylacetohydrazide
CAS 94090-75-2C15H13ClN2O
N-[(E)-(4-Chlorophenyl)methylideneamino]-2-phenylacetamide chemical structure, C15H13ClN2O, CAS 67759-87-9
N-[(E)-(4-Chlorophenyl)methylideneamino]-2-phenylacetamide
CAS 67759-87-9C15H13ClN2O
N'-(2,4-Dichlorobenzylidene)-2-phenylacetohydrazide chemical structure, C15H12Cl2N2O, CAS 343591-95-7
N'-(2,4-Dichlorobenzylidene)-2-phenylacetohydrazide
CAS 343591-95-7C15H12Cl2N2O
N'-[(E)-(4-Ethoxyphenyl)methylidene]-2-phenylacetohydrazide chemical structure, C17H18N2O2, CAS 343592-03-0
N'-[(E)-(4-Ethoxyphenyl)methylidene]-2-phenylacetohydrazide
CAS 343592-03-0C17H18N2O2
N'-(4-Methylbenzylidene)-2-phenylacetohydrazide chemical structure, C16H16N2O, CAS 4830-83-5
N'-(4-Methylbenzylidene)-2-phenylacetohydrazide
CAS 4830-83-5C16H16N2O
N-[(E)-(3-Iodo-4-methoxyphenyl)methylideneamino]-2-phenylacetamide chemical structure, C16H15IN2O2, CAS 330594-31-5
N-[(E)-(3-Iodo-4-methoxyphenyl)methylideneamino]-2-phenylacetamide
CAS 330594-31-5C16H15IN2O2
N-[(E)-(4-tert-Butylphenyl)methylideneamino]-2-phenylacetamide chemical structure, C19H22N2O, CAS 5326-13-6
N-[(E)-(4-tert-Butylphenyl)methylideneamino]-2-phenylacetamide
CAS 5326-13-6C19H22N2O
N-[(E)-(2,4-Dibromo-5-hydroxyphenyl)methylideneamino]-2-phenylacetamide chemical structure, C15H12Br2N2O2, CAS 341974-12-7
N-[(E)-(2,4-Dibromo-5-hydroxyphenyl)methylideneamino]-2-phenylacetamide
CAS 341974-12-7C15H12Br2N2O2
2-Phenyl-N-[(E)-(2,4,6-tribromo-3-hydroxyphenyl)methylideneamino]acetamide chemical structure, C15H11Br3N2O2, CAS 341974-14-9
2-Phenyl-N-[(E)-(2,4,6-tribromo-3-hydroxyphenyl)methylideneamino]acetamide
CAS 341974-14-9C15H11Br3N2O2
N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-2-phenylacetamide chemical structure, C15H12ClFN2O, CAS 341974-72-9
N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-2-phenylacetamide
CAS 341974-72-9C15H12ClFN2O
2-(4-Chlorophenyl)-N-[(E)-(4-chlorophenyl)methylideneamino]acetamide chemical structure, C15H12Cl2N2O, CAS 328901-79-7
2-(4-Chlorophenyl)-N-[(E)-(4-chlorophenyl)methylideneamino]acetamide
CAS 328901-79-7C15H12Cl2N2O
2-Hydroxy-N-[(E)-(2-nitrophenyl)methylideneamino]-2-phenylacetamide chemical structure, C15H13N3O4, CAS 221097-82-1
2-Hydroxy-N-[(E)-(2-nitrophenyl)methylideneamino]-2-phenylacetamide
CAS 221097-82-1C15H13N3O4
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-methoxy-2-phenylacetamide chemical structure, C16H14Cl2N2O2, CAS 1207549-02-7
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-methoxy-2-phenylacetamide
CAS 1207549-02-7C16H14Cl2N2O2
N-[(E)-(2,3-Dichlorophenyl)methylideneamino]-2-hydroxy-2-phenylacetamide chemical structure, C15H12Cl2N2O2, CAS 328937-95-7
N-[(E)-(2,3-Dichlorophenyl)methylideneamino]-2-hydroxy-2-phenylacetamide
CAS 328937-95-7C15H12Cl2N2O2
N-[(E)-(4-Fluorophenyl)methylideneamino]-2-hydroxy-2-phenylacetamide chemical structure, C15H13FN2O2, CAS 351189-83-8
N-[(E)-(4-Fluorophenyl)methylideneamino]-2-hydroxy-2-phenylacetamide
CAS 351189-83-8C15H13FN2O2
2-Methoxy-2-phenyl-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]acetamide chemical structure, C19H22N2O2, CAS 5539-79-7
2-Methoxy-2-phenyl-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]acetamide
CAS 5539-79-7C19H22N2O2