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Murcko scaffold

Ring system with 2 rings and 13 atoms

70 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
70
With full pages
11
Scaffold SMILES

c1ccc(OCc2cncs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCc2cncs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 70 chemicals

2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]benzonitrile chemical structure, C11H7ClN2OS, CAS 860787-01-5
2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]benzonitrile
CAS 860787-01-5C11H7ClN2OS
2-Chloro-5-[(2,4-dimethylphenoxy)methyl]-1,3-thiazole chemical structure, C12H12ClNOS, CAS 303987-44-2
2-Chloro-5-[(2,4-dimethylphenoxy)methyl]-1,3-thiazole
CAS 303987-44-2C12H12ClNOS
Methyl 2-{4-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenyl}acetate chemical structure, C13H12ClNO3S, CAS 478064-76-5
Methyl 2-{4-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenyl}acetate
CAS 478064-76-5C13H12ClNO3S
(E)-3-{4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-3-methoxyphenyl}-2-propenoic acid chemical structure, C14H12ClNO4S, CAS 866050-79-5
(E)-3-{4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-3-methoxyphenyl}-2-propenoic acid
CAS 866050-79-5C14H12ClNO4S
2-Chloro-5-[(4-methoxyphenoxy)methyl]-1,3-thiazole chemical structure, C11H10ClNO2S, CAS 339018-20-1
2-Chloro-5-[(4-methoxyphenoxy)methyl]-1,3-thiazole
CAS 339018-20-1C11H10ClNO2S
(2-Chloro-1,3-thiazol-5-yl)methyl phenyl ether chemical structure, C10H8ClNOS, CAS 339018-23-4
(2-Chloro-1,3-thiazol-5-yl)methyl phenyl ether
CAS 339018-23-4C10H8ClNOS
N-{4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}acetamide chemical structure, C12H11ClN2O2S, CAS 339018-25-6
N-{4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}acetamide
CAS 339018-25-6C12H11ClN2O2S
2-Chloro-5-[(4-nitrophenoxy)methyl]-1,3-thiazole chemical structure, C10H7ClN2O3S, CAS 339018-26-7
2-Chloro-5-[(4-nitrophenoxy)methyl]-1,3-thiazole
CAS 339018-26-7C10H7ClN2O3S
2-Chloro-5-[(2,4-dichlorophenoxy)methyl]-1,3-thiazole chemical structure, C10H6Cl3NOS, CAS 339018-27-8
2-Chloro-5-[(2,4-dichlorophenoxy)methyl]-1,3-thiazole
CAS 339018-27-8C10H6Cl3NOS
2-Chloro-5-[(3-methylphenoxy)methyl]-1,3-thiazole chemical structure, C11H10ClNOS, CAS 339018-28-9
2-Chloro-5-[(3-methylphenoxy)methyl]-1,3-thiazole
CAS 339018-28-9C11H10ClNOS
2-Chloro-5-[(4-fluorophenoxy)methyl]-1,3-thiazole chemical structure, C10H7ClFNOS, CAS 339018-31-4
2-Chloro-5-[(4-fluorophenoxy)methyl]-1,3-thiazole
CAS 339018-31-4C10H7ClFNOS
2-Chloro-5-[[4-(1,1-dimethylethyl)phenoxy]methyl]thiazole chemical structure, C14H16ClNOS, CAS 339018-34-7
2-Chloro-5-[[4-(1,1-dimethylethyl)phenoxy]methyl]thiazole
CAS 339018-34-7C14H16ClNOS
2-Chloro-5-{[3-(trifluoromethyl)phenoxy]methyl}-1,3-thiazole chemical structure, C11H7ClF3NOS, CAS 339018-43-8
2-Chloro-5-{[3-(trifluoromethyl)phenoxy]methyl}-1,3-thiazole
CAS 339018-43-8C11H7ClF3NOS
2-({4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylene)malononitrile chemical structure, C14H8ClN3OS, CAS 692732-78-8
2-({4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylene)malononitrile
CAS 692732-78-8C14H8ClN3OS
2-({4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-3-methoxyphenyl}methylene)malononitrile chemical structure, C15H10ClN3O2S, CAS 692732-81-3
2-({4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-3-methoxyphenyl}methylene)malononitrile
CAS 692732-81-3C15H10ClN3O2S
2-Chloro-5-{[2-nitro-4-(trifluoromethyl)phenoxy]methyl}-1,3-thiazole chemical structure, C11H6ClF3N2O3S, CAS 339104-87-9
2-Chloro-5-{[2-nitro-4-(trifluoromethyl)phenoxy]methyl}-1,3-thiazole
CAS 339104-87-9C11H6ClF3N2O3S
N-{2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}acetamide chemical structure, C12H11ClN2O2S, CAS 320423-44-7
N-{2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}acetamide
CAS 320423-44-7C12H11ClN2O2S
{4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methanol chemical structure, C11H10ClNO2S, CAS 320423-67-4
{4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methanol
CAS 320423-67-4C11H10ClNO2S
2-Chloro-5-[(4-chloro-3-fluorophenoxy)methyl]-1,3-thiazole chemical structure, C10H6Cl2FNOS, CAS 338393-41-2
2-Chloro-5-[(4-chloro-3-fluorophenoxy)methyl]-1,3-thiazole
CAS 338393-41-2C10H6Cl2FNOS
2-({2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylene)malononitrile chemical structure, C14H8ClN3OS, CAS 338393-71-8
2-({2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylene)malononitrile
CAS 338393-71-8C14H8ClN3OS
5-(Phenoxymethyl)thiazol-2-amine chemical structure, C10H10N2OS, CAS 611196-39-5
5-(Phenoxymethyl)thiazol-2-amine
CAS 611196-39-5C10H10N2OS
3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]benzaldehyde chemical structure, C11H8ClNO2S, CAS 439094-98-1
3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]benzaldehyde
CAS 439094-98-1C11H8ClNO2S
1-{2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}-1-ethanone chemical structure, C12H10ClNO2S, CAS 320423-63-0
1-{2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}-1-ethanone
CAS 320423-63-0C12H10ClNO2S
Methyl 3-[(2-chloro-1,3-thiazol-5-yl)methoxy]benzenecarboxylate chemical structure, C12H10ClNO3S, CAS 338393-42-3
Methyl 3-[(2-chloro-1,3-thiazol-5-yl)methoxy]benzenecarboxylate
CAS 338393-42-3C12H10ClNO3S