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Murcko scaffold

Ring system with 2 rings and 14 atoms

84 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
84
With full pages
11
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCOC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCOC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

4,4-Dimethyl-3-[(4-nitrophenyl)sulfonyl]-1,3-oxazolane chemical structure, C11H14N2O5S, CAS 866157-30-4
4,4-Dimethyl-3-[(4-nitrophenyl)sulfonyl]-1,3-oxazolane
CAS 866157-30-4C11H14N2O5S
4,4-Dimethyl-3-[(4-methylphenyl)sulfonyl]-1,3-oxazolane chemical structure, C12H17NO3S, CAS 866157-32-6
4,4-Dimethyl-3-[(4-methylphenyl)sulfonyl]-1,3-oxazolane
CAS 866157-32-6C12H17NO3S
4,4-Dimethyl-3-{[2-(trifluoromethyl)phenyl]sulfonyl}-1,3-oxazolane chemical structure, C12H14F3NO3S, CAS 866157-31-5
4,4-Dimethyl-3-{[2-(trifluoromethyl)phenyl]sulfonyl}-1,3-oxazolane
CAS 866157-31-5C12H14F3NO3S
N1-(2-(dimethylamino)ethyl)-N2-((3-((4-nitrophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C16H23N5O7S, CAS 868981-91-3
N1-(2-(dimethylamino)ethyl)-N2-((3-((4-nitrophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868981-91-3C16H23N5O7S
N1-(2-(diethylamino)ethyl)-N2-((3-((4-nitrophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C18H27N5O7S, CAS 868981-85-5
N1-(2-(diethylamino)ethyl)-N2-((3-((4-nitrophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868981-85-5C18H27N5O7S
5-Methoxy-2,2-dimethyl-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine chemical structure, C13H19NO4S, CAS 52180-34-4
5-Methoxy-2,2-dimethyl-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine
CAS 52180-34-4C13H19NO4S
5-Ethoxy-2,2-dimethyl-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine chemical structure, C14H21NO4S, CAS 52180-35-5
5-Ethoxy-2,2-dimethyl-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine
CAS 52180-35-5C14H21NO4S
5-Methoxy-2,2-dimethyl-3-(4-nitrobenzene-1-sulfonyl)-1,3-oxazolidine chemical structure, C12H16N2O6S, CAS 62472-50-8
5-Methoxy-2,2-dimethyl-3-(4-nitrobenzene-1-sulfonyl)-1,3-oxazolidine
CAS 62472-50-8C12H16N2O6S
5-Methoxy-2-methyl-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine chemical structure, C12H17NO4S, CAS 62642-51-7
5-Methoxy-2-methyl-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine
CAS 62642-51-7C12H17NO4S
2-Ethyl-5-methoxy-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine chemical structure, C13H19NO4S, CAS 62642-52-8
2-Ethyl-5-methoxy-3-(4-methylbenzene-1-sulfonyl)-1,3-oxazolidine
CAS 62642-52-8C13H19NO4S
5-Methoxy-3-(4-methylbenzene-1-sulfonyl)-2-(propan-2-yl)-1,3-oxazolidine chemical structure, C14H21NO4S, CAS 62642-53-9
5-Methoxy-3-(4-methylbenzene-1-sulfonyl)-2-(propan-2-yl)-1,3-oxazolidine
CAS 62642-53-9C14H21NO4S
4-Oxazolidinecarboxaldehyde, 2,2,5-trimethyl-3-(phenylsulfonyl)-, (4R-trans)- chemical structure, C13H17NO4S, CAS 141990-08-1
4-Oxazolidinecarboxaldehyde, 2,2,5-trimethyl-3-(phenylsulfonyl)-, (4R-trans)-
CAS 141990-08-1C13H17NO4S
N1-methyl-N2-((3-((4-nitrophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C13H16N4O7S, CAS 868982-22-3
N1-methyl-N2-((3-((4-nitrophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868982-22-3C13H16N4O7S
N1-(2-(diethylamino)ethyl)-N2-((3-((4-fluorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C18H27FN4O5S, CAS 868980-86-3
N1-(2-(diethylamino)ethyl)-N2-((3-((4-fluorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868980-86-3C18H27FN4O5S
N-[2-(Diethylamino)ethyl]-N'-{[3-(4-methoxybenzenesulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide chemical structure, C19H30N4O6S, CAS 868981-15-1
N-[2-(Diethylamino)ethyl]-N'-{[3-(4-methoxybenzenesulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide
CAS 868981-15-1C19H30N4O6S
N1-(2-(dimethylamino)ethyl)-N2-((3-((4-methoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C17H26N4O6S, CAS 868981-20-8
N1-(2-(dimethylamino)ethyl)-N2-((3-((4-methoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868981-20-8C17H26N4O6S
N1-(2-(diethylamino)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C18H28N4O5S, CAS 868981-52-6
N1-(2-(diethylamino)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868981-52-6C18H28N4O5S
N1-(2-(dimethylamino)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C16H24N4O5S, CAS 868981-58-2
N1-(2-(dimethylamino)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868981-58-2C16H24N4O5S
N'-{[3-(Benzenesulfonyl)-1,3-oxazolidin-2-yl]methyl}-N-[3-(dimethylamino)propyl]ethanediamide chemical structure, C17H26N4O5S, CAS 868981-59-3
N'-{[3-(Benzenesulfonyl)-1,3-oxazolidin-2-yl]methyl}-N-[3-(dimethylamino)propyl]ethanediamide
CAS 868981-59-3C17H26N4O5S
N-[3-(Dimethylamino)propyl]-N'-{[3-(4-nitrobenzenesulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide chemical structure, C17H25N5O7S, CAS 868981-92-4
N-[3-(Dimethylamino)propyl]-N'-{[3-(4-nitrobenzenesulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide
CAS 868981-92-4C17H25N5O7S
N1-(2-(dimethylamino)ethyl)-N2-((3-(mesitylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C19H30N4O5S, CAS 868982-65-4
N1-(2-(dimethylamino)ethyl)-N2-((3-(mesitylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868982-65-4C19H30N4O5S
N1-(3-(dimethylamino)propyl)-N2-((3-(mesitylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C20H32N4O5S, CAS 868982-66-5
N1-(3-(dimethylamino)propyl)-N2-((3-(mesitylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868982-66-5C20H32N4O5S
N1-(2-(diethylamino)ethyl)-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C20H32N4O7S, CAS 868982-99-4
N1-(2-(diethylamino)ethyl)-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868982-99-4C20H32N4O7S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)-N2-(2-(dimethylamino)ethyl)oxalamide chemical structure, C18H28N4O7S, CAS 868983-04-4
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)-N2-(2-(dimethylamino)ethyl)oxalamide
CAS 868983-04-4C18H28N4O7S