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Murcko scaffold

Ring system with 2 rings and 15 atoms

59 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
59
With full pages
4
Scaffold SMILES

O=S(=O)(Cc1cccs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Cc1cccs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

2-(Benzenesulfonyl)-2-(thiophen-2-yl)acetonitrile chemical structure, C12H9NO2S2, CAS 130138-43-1
2-(Benzenesulfonyl)-2-(thiophen-2-yl)acetonitrile
CAS 130138-43-1C12H9NO2S2
2-Thiopheneethanamine, beta-[(4-chlorophenyl)sulfonyl]- chemical structure, C12H12ClNO2S2, CAS 903094-84-8
2-Thiopheneethanamine, beta-[(4-chlorophenyl)sulfonyl]-
CAS 903094-84-8C12H12ClNO2S2
2-[(4-Methylphenyl)sulphonyl]-2-(2-thienyl)ethylamine chemical structure, C13H15NO2S2, CAS 903094-04-2
2-[(4-Methylphenyl)sulphonyl]-2-(2-thienyl)ethylamine
CAS 903094-04-2C13H15NO2S2
2-[(4-Methoxyphenyl)sulphonyl]-2-(2-thienyl)ethylamine chemical structure, C13H15NO3S2, CAS 903094-00-8
2-[(4-Methoxyphenyl)sulphonyl]-2-(2-thienyl)ethylamine
CAS 903094-00-8C13H15NO3S2
2-(Phenylsulphonyl)-2-(2-thienyl)ethylamine chemical structure, C12H13NO2S2, CAS 903094-46-2
2-(Phenylsulphonyl)-2-(2-thienyl)ethylamine
CAS 903094-46-2C12H13NO2S2
N-[2-(4-Fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]methanesulfonamide chemical structure, C13H14FNO4S3, CAS 896346-21-7
N-[2-(4-Fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]methanesulfonamide
CAS 896346-21-7C13H14FNO4S3
2-((4-Fluorophenyl)sulfonyl)-2-(thiophen-2-yl)ethanamine hydrochloride chemical structure, C12H13ClFNO2S2, CAS 1094398-06-7
2-((4-Fluorophenyl)sulfonyl)-2-(thiophen-2-yl)ethanamine hydrochloride
CAS 1094398-06-7C12H13ClFNO2S2
N-[2-(4-Fluoro-3-methylbenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,2-dimethylpropanamide chemical structure, C18H22FNO3S2, CAS 941986-85-2
N-[2-(4-Fluoro-3-methylbenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,2-dimethylpropanamide
CAS 941986-85-2C18H22FNO3S2
N-[2-(4-Fluoro-3-methylbenzenesulfonyl)-2-(thiophen-2-yl)ethyl]butanamide chemical structure, C17H20FNO3S2, CAS 923150-81-6
N-[2-(4-Fluoro-3-methylbenzenesulfonyl)-2-(thiophen-2-yl)ethyl]butanamide
CAS 923150-81-6C17H20FNO3S2
Ethyl 2-oxo-2-((2-(phenylsulfonyl)-2-(thiophen-2-yl)ethyl)amino)acetate chemical structure, C16H17NO5S2, CAS 896335-10-7
Ethyl 2-oxo-2-((2-(phenylsulfonyl)-2-(thiophen-2-yl)ethyl)amino)acetate
CAS 896335-10-7C16H17NO5S2
Ethyl 2-oxo-2-((2-(thiophen-2-yl)-2-tosylethyl)amino)acetate chemical structure, C17H19NO5S2, CAS 896343-46-7
Ethyl 2-oxo-2-((2-(thiophen-2-yl)-2-tosylethyl)amino)acetate
CAS 896343-46-7C17H19NO5S2
N1-(3-(dimethylamino)propyl)-N2-(2-((4-fluorophenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)oxalamide chemical structure, C19H24FN3O4S2, CAS 898413-07-5
N1-(3-(dimethylamino)propyl)-N2-(2-((4-fluorophenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)oxalamide
CAS 898413-07-5C19H24FN3O4S2
Ethyl 2-((2-((4-fluorophenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)amino)-2-oxoacetate chemical structure, C16H16FNO5S2, CAS 896329-63-8
Ethyl 2-((2-((4-fluorophenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)amino)-2-oxoacetate
CAS 896329-63-8C16H16FNO5S2
N-[2-(Phenylsulfonyl)-2-(2-thienyl)ethyl]ethanesulfonamide chemical structure, C14H17NO4S3, CAS 896341-40-5
N-[2-(Phenylsulfonyl)-2-(2-thienyl)ethyl]ethanesulfonamide
CAS 896341-40-5C14H17NO4S3
N-(2-(Thiophen-2-yl)-2-tosylethyl)ethanesulfonamide chemical structure, C15H19NO4S3, CAS 896343-37-6
N-(2-(Thiophen-2-yl)-2-tosylethyl)ethanesulfonamide
CAS 896343-37-6C15H19NO4S3
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]butanamide chemical structure, C17H21NO4S2, CAS 946348-03-4
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]butanamide
CAS 946348-03-4C17H21NO4S2
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3,3-dimethylbutanamide chemical structure, C19H25NO4S2, CAS 946285-06-9
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3,3-dimethylbutanamide
CAS 946285-06-9C19H25NO4S2
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3-methylbutanamide chemical structure, C18H23NO4S2, CAS 946348-33-0
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3-methylbutanamide
CAS 946348-33-0C18H23NO4S2
N-(2-((4-Methoxyphenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)acetamide chemical structure, C15H17NO4S2, CAS 946348-45-4
N-(2-((4-Methoxyphenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)acetamide
CAS 946348-45-4C15H17NO4S2
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,2-dimethylpropanamide chemical structure, C18H23NO4S2, CAS 946297-76-3
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,2-dimethylpropanamide
CAS 946297-76-3C18H23NO4S2
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]propanamide chemical structure, C16H19NO4S2, CAS 946348-49-8
N-[2-(4-Methoxybenzenesulfonyl)-2-(thiophen-2-yl)ethyl]propanamide
CAS 946348-49-8C16H19NO4S2
N-(2-((4-Fluoro-3-methylphenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)-3,3-dimethylbutanamide chemical structure, C19H24FNO3S2, CAS 946242-82-6
N-(2-((4-Fluoro-3-methylphenyl)sulfonyl)-2-(thiophen-2-yl)ethyl)-3,3-dimethylbutanamide
CAS 946242-82-6C19H24FNO3S2
N-[2-(4-Fluoro-3-methylbenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3-methylbutanamide chemical structure, C18H22FNO3S2, CAS 946298-08-4
N-[2-(4-Fluoro-3-methylbenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3-methylbutanamide
CAS 946298-08-4C18H22FNO3S2
N-[2-[(4-Fluoro-3-methylphenyl)sulfonyl]-2-(2-thienyl)ethyl]acetamide chemical structure, C15H16FNO3S2, CAS 946264-64-8
N-[2-[(4-Fluoro-3-methylphenyl)sulfonyl]-2-(2-thienyl)ethyl]acetamide
CAS 946264-64-8C15H16FNO3S2