CompoundList
Sign in
Murcko scaffold

1-(Phenylsulfonyl)-4-(2-(4-pyridyl)ethyl)piperazine scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
6
With full pages
3
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(CCc2ccncc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Phenylsulfonyl)-4-(2-(4-pyridyl)ethyl)piperazine page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(CCc2ccncc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

1-(4-Methylbenzenesulfonyl)-4-[2-(pyridin-4-yl)ethyl]piperazine chemical structure, C18H23N3O2S, CAS 742095-22-3
1-(4-Methylbenzenesulfonyl)-4-[2-(pyridin-4-yl)ethyl]piperazine
CAS 742095-22-3C18H23N3O2S
Ethyl 4-({4-[2-(pyridin-4-yl)ethyl]piperazin-1-yl}sulfonyl)benzoate chemical structure, C20H25N3O4S, CAS 790707-56-1
Ethyl 4-({4-[2-(pyridin-4-yl)ethyl]piperazin-1-yl}sulfonyl)benzoate
CAS 790707-56-1C20H25N3O4S
1-(4-Chlorophenyl)sulfonyl-4-(2-pyridin-4-ylethyl)piperazine chemical structure, C17H20ClN3O2S, CAS 792940-17-1
1-(4-Chlorophenyl)sulfonyl-4-(2-pyridin-4-ylethyl)piperazine
CAS 792940-17-1C17H20ClN3O2S
1-(Phenylsulfonyl)-4-(2-(4-pyridyl)ethyl)piperazine chemical structure, C17H21N3O2S, CAS 923879-78-1
1-(Phenylsulfonyl)-4-(2-(4-pyridyl)ethyl)piperazine
CAS 923879-78-1C17H21N3O2S
1-(4-Fluorobenzenesulfonyl)-4-[2-(pyridin-4-yl)ethyl]piperazine chemical structure, C17H20FN3O2S, CAS 924019-96-5
1-(4-Fluorobenzenesulfonyl)-4-[2-(pyridin-4-yl)ethyl]piperazine
CAS 924019-96-5C17H20FN3O2S
1-(4-Methoxybenzenesulfonyl)-4-[2-(pyridin-4-yl)ethyl]piperazine chemical structure, C18H23N3O3S, CAS 924012-86-2
1-(4-Methoxybenzenesulfonyl)-4-[2-(pyridin-4-yl)ethyl]piperazine
CAS 924012-86-2C18H23N3O3S