Murcko scaffold
Ring system with 4 rings and 23 atoms
780 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 780
- With full pages
- 5
Scaffold SMILES
O=C(NC1CCOC1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 780 chemicals
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)oxolane-3-carboxylic acid
CAS 1132879-21-0C20H19NO5
![4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolane-3-carboxylic acid chemical structure, C21H21NO5, CAS 1503723-14-5](/s/MDEPEPZTYBCYRP-UHFFFAOYSA-N.svg)
4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolane-3-carboxylic acid
CAS 1503723-14-5C21H21NO5
![3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)oxolane-3-carboxylic acid chemical structure, C21H21NO5, CAS 1695959-63-7](/s/AURQPGDIHILZJC-UHFFFAOYSA-N.svg)
3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)oxolane-3-carboxylic acid
CAS 1695959-63-7C21H21NO5
![rac-(9H-Fluoren-9-yl)methyl N-[(3R,4S)-4-hydroxyoxolan-3-yl]carbamate chemical structure, C19H19NO4, CAS 1932138-80-1](/s/SAQSZNBNWRHPDN-QZTJIDSGSA-N.svg)
rac-(9H-Fluoren-9-yl)methyl N-[(3R,4S)-4-hydroxyoxolan-3-yl]carbamate
CAS 1932138-80-1C19H19NO4
![(9H-Fluoren-9-yl)methyl N-[3-(hydroxymethyl)oxolan-3-yl]carbamate chemical structure, C20H21NO4, CAS 1857725-48-4](/s/NLCCCFOZXPZHSC-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(hydroxymethyl)oxolan-3-yl]carbamate
CAS 1857725-48-4C20H21NO4
![2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]acetic acid chemical structure, C21H21NO5, CAS 1935458-78-8](/s/IQUDNPWJDFDTES-UHFFFAOYSA-N.svg)
2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]acetic acid
CAS 1935458-78-8C21H21NO5
![rac-(2R,3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-2-carboxylic acid chemical structure, C20H19NO5, CAS 2138266-64-3](/s/NUCSYZBFEPVWSU-ZWKOTPCHSA-N.svg)
rac-(2R,3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-2-carboxylic acid
CAS 2138266-64-3C20H19NO5
![3-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]propanoic acid chemical structure, C22H23NO5, CAS 2219373-89-2](/s/JKHXXGWSFYCSNO-UHFFFAOYSA-N.svg)
3-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]propanoic acid
CAS 2219373-89-2C22H23NO5
![rac-(3R,4S)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-3-carboxylic acid chemical structure, C20H19NO5, CAS 2219378-56-8](/s/SXJQMBNBCLUFOK-MSOLQXFVSA-N.svg)
rac-(3R,4S)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-3-carboxylic acid
CAS 2219378-56-8C20H19NO5
![2-[4-(9H-Fluoren-9-ylmethoxycarbonylamino)oxolan-3-yl]acetic acid chemical structure, C21H21NO5, CAS 2413877-86-6](/s/CFUQFAWZSPWKKC-UHFFFAOYSA-N.svg)
2-[4-(9H-Fluoren-9-ylmethoxycarbonylamino)oxolan-3-yl]acetic acid
CAS 2413877-86-6C21H21NO5
![3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}-2,2-dimethylpropanoic acid chemical structure, C26H30N2O6, CAS 2172178-29-7](/s/XQLZIJZYIXUUML-UHFFFAOYSA-N.svg)
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}-2,2-dimethylpropanoic acid
CAS 2172178-29-7C26H30N2O6
![(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-4-methylpentanoic acid chemical structure, C26H30N2O6, CAS 2648911-71-9](/s/CKJHALGHWCJAOJ-CHQVSRGASA-N.svg)
(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-4-methylpentanoic acid
CAS 2648911-71-9C26H30N2O6
![2-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}methyl)-3-methylbutanoic acid chemical structure, C26H30N2O6, CAS 2171641-85-1](/s/MIOPWTDQAJLQEI-UHFFFAOYSA-N.svg)
2-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}methyl)-3-methylbutanoic acid
CAS 2171641-85-1C26H30N2O6
![2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}butanoic acid chemical structure, C24H26N2O6, CAS 2171549-63-4](/s/XKHSURPFTSDEND-UHFFFAOYSA-N.svg)
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}butanoic acid
CAS 2171549-63-4C24H26N2O6
![3-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}methyl)-4-methylpentanoic acid chemical structure, C27H32N2O6, CAS 2171946-01-1](/s/FWDPWHUAUWABHQ-UHFFFAOYSA-N.svg)
3-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}methyl)-4-methylpentanoic acid
CAS 2171946-01-1C27H32N2O6
![3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2,2-dimethylpropanoic acid chemical structure, C25H28N2O6, CAS 2172366-36-6](/s/OUAMLDVQJBWJCM-UHFFFAOYSA-N.svg)
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2,2-dimethylpropanoic acid
CAS 2172366-36-6C25H28N2O6
![2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}hex-4-ynoic acid chemical structure, C26H26N2O6, CAS 2171609-06-4](/s/HVANNRXILJKNAF-UHFFFAOYSA-N.svg)
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}hex-4-ynoic acid
CAS 2171609-06-4C26H26N2O6
![2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-5-methoxypentanoic acid chemical structure, C26H30N2O7, CAS 2171491-08-8](/s/JGSHTVMKSGWWKN-UHFFFAOYSA-N.svg)
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-5-methoxypentanoic acid
CAS 2171491-08-8C26H30N2O7
![(2R)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}-3-hydroxypropanoic acid chemical structure, C24H26N2O7, CAS 2648914-95-6](/s/XCXIMVQBCXJGJH-KDARRYODSA-N.svg)
(2R)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}-3-hydroxypropanoic acid
CAS 2648914-95-6C24H26N2O7
![2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2,5-dimethyloxolan-3-yl]acetic acid chemical structure, C23H25NO5, CAS 2171603-20-4](/s/GTCNLZYDUJWGAO-UHFFFAOYSA-N.svg)
2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2,5-dimethyloxolan-3-yl]acetic acid
CAS 2171603-20-4C23H25NO5
![3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2-hydroxypropanoic acid chemical structure, C23H24N2O7, CAS 2172143-68-7](/s/XMPKDBHSYNDLOR-UHFFFAOYSA-N.svg)
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2-hydroxypropanoic acid
CAS 2172143-68-7C23H24N2O7
![2-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}methyl)-2-methylbutanoic acid chemical structure, C26H30N2O6, CAS 2172082-46-9](/s/RIOYIEZOUOPJQL-UHFFFAOYSA-N.svg)
2-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}methyl)-2-methylbutanoic acid
CAS 2172082-46-9C26H30N2O6
![4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}but-2-enoic acid chemical structure, C24H24N2O6, CAS 2172633-04-2](/s/GFFFCLFLLKDCIT-BJMVGYQFSA-N.svg)
4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}but-2-enoic acid
CAS 2172633-04-2C24H24N2O6
![5-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}pentanoic acid chemical structure, C26H30N2O6, CAS 2172464-05-8](/s/YXKJHCZHOLATSU-UHFFFAOYSA-N.svg)
5-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}pentanoic acid
CAS 2172464-05-8C26H30N2O6
- 2-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}methyl)pentanoic acid2172183-58-1C26H30N2O6
- (2S)-4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}-2-hydroxybutanoic acid2171419-07-9C25H28N2O7
- 4-{1-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]-N-methylformamido}butanoic acid2172049-14-6C25H28N2O6
- (2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}hexanoic acid2648936-27-8C26H30N2O6
- 2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}-4,4,4-trifluorobutanoic acid2171759-92-3C24H23F3N2O6
- (2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}pentanoic acid2648924-66-5C25H28N2O6
- (3R)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}butanoic acid2171424-70-5C25H28N2O6
- (2R)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-3-hydroxypropanoic acid2648935-31-1C23H24N2O7
- 3-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2-hydroxy-2-methylpropanoic acid2172501-91-4C24H26N2O7
- 4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}pentanoic acid2172520-24-8C25H28N2O6
- 3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}butanoic acid2171984-55-5C25H28N2O6
- 3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2-hydroxy-2-methylpropanoic acid2171821-61-5C24H26N2O7
- 2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}acetic acid2172522-27-7C22H22N2O6
- 2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2-methylbutanoic acid2648982-48-1C25H28N2O6
- 4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-4-methylpentanoic acid2172530-14-0C26H30N2O6
- 3-(2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}ethoxy)propanoic acid2172514-97-3C25H28N2O7
- 4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-2,2-dimethylbutanoic acid2171836-60-3C26H30N2O6
- 2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}pent-4-enoic acid2171618-16-7C25H26N2O6
- (3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}heptanoic acid2171435-02-0C27H32N2O6
- 3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}heptanoic acid2172513-65-2C27H32N2O6
- 4-{1-[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]-N-(propan-2-yl)formamido}butanoic acid2172328-55-9C27H32N2O6
- 3-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}heptanoic acid2171735-44-5C27H32N2O6
- (2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}-3,3-dimethylbutanoic acid2171453-65-7C27H32N2O6
- (2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}-4-(methylsulfanyl)butanoic acid2648931-03-5C25H28N2O6S
Related scaffolds
Same ring framework with different atoms or bond orders
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