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Murcko scaffold

Ring system with 4 rings and 24 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
14
With full pages
2
Scaffold SMILES

O=C(NC1CCNC1=O)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCNC1=O)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Fmoc-Freidinger's lactam chemical structure, C25H28N2O5, CAS 145484-45-3
Fmoc-Freidinger's lactam
CAS 145484-45-3C25H28N2O5
N-Fmoc-Freidinger's lactam chemical structure, C24H26N2O5, CAS 957507-85-6
N-Fmoc-Freidinger's lactam
CAS 957507-85-6C24H26N2O5
3-(Fmoc-amino)-2-oxo-1-pyrrolidineacetic Acid chemical structure, C21H20N2O5, CAS 317354-95-3
3-(Fmoc-amino)-2-oxo-1-pyrrolidineacetic Acid
CAS 317354-95-3C21H20N2O5
3-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-oxopyrrolidin-1-yl]propanoic acid chemical structure, C22H22N2O5, CAS 2137472-97-8
3-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-oxopyrrolidin-1-yl]propanoic acid
CAS 2137472-97-8C22H22N2O5
(3R)-Fmoc-2-oxo-1-Pyrrolidineacetic acid chemical structure, C21H20N2O5, CAS 143129-76-4
(3R)-Fmoc-2-oxo-1-Pyrrolidineacetic acid
CAS 143129-76-4C21H20N2O5
Fmoc-Freidinger's lactam chemical structure, C25H28N2O5, CAS 1046761-84-5
Fmoc-Freidinger's lactam
CAS 1046761-84-5C25H28N2O5
(S)-2-((R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopyrrolidin-1-yl)propanoic acid chemical structure, C22H22N2O5, CAS 195607-50-2
(S)-2-((R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopyrrolidin-1-yl)propanoic acid
CAS 195607-50-2C22H22N2O5
(9H-Fluoren-9-yl)methyl N-[(3S,5R)-5-(hydroxymethyl)-2-oxopyrrolidin-3-yl]carbamate chemical structure, C20H20N2O4, CAS 2446818-40-0
(9H-Fluoren-9-yl)methyl N-[(3S,5R)-5-(hydroxymethyl)-2-oxopyrrolidin-3-yl]carbamate
CAS 2446818-40-0C20H20N2O4
(3S)-Fmoc-2-oxo-1-Pyrrolidineacetic acid chemical structure, C21H20N2O5, CAS 143129-77-5
(3S)-Fmoc-2-oxo-1-Pyrrolidineacetic acid
CAS 143129-77-5C21H20N2O5
4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C20H18N2O5, CAS 2137447-21-1
4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopyrrolidine-3-carboxylic acid
CAS 2137447-21-1C20H18N2O5
rac-(3R,4S)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C20H18N2O5, CAS 2227694-04-2
rac-(3R,4S)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopyrrolidine-3-carboxylic acid
CAS 2227694-04-2C20H18N2O5
(9H-Fluoren-9-yl)methyl N-[(3R,5R)-5-(hydroxymethyl)-2-oxopyrrolidin-3-yl]carbamate chemical structure, C20H20N2O4, CAS 2770452-89-4
(9H-Fluoren-9-yl)methyl N-[(3R,5R)-5-(hydroxymethyl)-2-oxopyrrolidin-3-yl]carbamate
CAS 2770452-89-4C20H20N2O4
(9H-Fluoren-9-yl)methyl N-methyl-N-[2-oxo-1-(prop-2-en-1-yl)pyrrolidin-3-yl]carbamate chemical structure, C23H24N2O3, CAS 2770486-34-3
(9H-Fluoren-9-yl)methyl N-methyl-N-[2-oxo-1-(prop-2-en-1-yl)pyrrolidin-3-yl]carbamate
CAS 2770486-34-3C23H24N2O3
(S)-2-((S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopyrrolidin-1-yl)propanoic acid chemical structure, C22H22N2O5, CAS 3034578-64-5
(S)-2-((S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopyrrolidin-1-yl)propanoic acid
CAS 3034578-64-5C22H22N2O5