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Murcko scaffold

Ring system with 4 rings and 23 atoms

1,683 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
1,683
With full pages
15
Scaffold SMILES

O=C(NC1CCCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,683 chemicals

Fmoc-cycloleucine chemical structure, C21H21NO4, CAS 117322-30-2
Fmoc-cycloleucine
CAS 117322-30-2C21H21NO4
3-(9H-Fluoren-9-ylmethoxycarbonylamino)cyclopentanecarboxylic acid chemical structure, C21H21NO4, CAS 929976-34-1
3-(9H-Fluoren-9-ylmethoxycarbonylamino)cyclopentanecarboxylic acid
CAS 929976-34-1C21H21NO4
(1S,2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentane-1-carboxylic acid chemical structure, C21H21NO4, CAS 359586-64-4
(1S,2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentane-1-carboxylic acid
CAS 359586-64-4C21H21NO4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentane-1-carboxylic acid chemical structure, C21H21NO4, CAS 282524-97-4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentane-1-carboxylic acid
CAS 282524-97-4C21H21NO4
rac-(1R,3S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentane-1-carboxylic acid chemical structure, C21H21NO4, CAS 220497-67-6
rac-(1R,3S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentane-1-carboxylic acid
CAS 220497-67-6C21H21NO4
(+)-(1S,3R)-N-Fmoc-3-aminocyclopentane-1-carboxylic acid chemical structure, C21H21NO4, CAS 220497-66-5
(+)-(1S,3R)-N-Fmoc-3-aminocyclopentane-1-carboxylic acid
CAS 220497-66-5C21H21NO4
(1S,3S)-3-(Fmoc-amino)cyclopentanecarboxylic acid chemical structure, C21H21NO4, CAS 872174-19-1
(1S,3S)-3-(Fmoc-amino)cyclopentanecarboxylic acid
CAS 872174-19-1C21H21NO4
(1R,3R)-3-(Fmoc-amino)cyclopentanecarboxylic acid chemical structure, C21H21NO4, CAS 872174-18-0
(1R,3R)-3-(Fmoc-amino)cyclopentanecarboxylic acid
CAS 872174-18-0C21H21NO4
(9H-Fluoren-9-yl)methyl N-[(1S,2S)-2-(hydroxymethyl)cyclopentyl]carbamate chemical structure, C21H23NO3, CAS 359586-63-3
(9H-Fluoren-9-yl)methyl N-[(1S,2S)-2-(hydroxymethyl)cyclopentyl]carbamate
CAS 359586-63-3C21H23NO3
(1R,2R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylic acid chemical structure, C21H21NO4, CAS 359586-69-9
(1R,2R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylic acid
CAS 359586-69-9C21H21NO4
cis-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylic acid chemical structure, C21H21NO4, CAS 1203556-26-6
cis-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentanecarboxylic acid
CAS 1203556-26-6C21H21NO4
N-Fmoc-(1R,2S)-2-Amino-1-cyclopentanecarboxylic acid chemical structure, C21H21NO4, CAS 352707-76-7
N-Fmoc-(1R,2S)-2-Amino-1-cyclopentanecarboxylic acid
CAS 352707-76-7C21H21NO4
1-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-cyclopentanecarboxylic acid methyl ester chemical structure, C22H23NO5, CAS 924817-61-8
1-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-cyclopentanecarboxylic acid methyl ester
CAS 924817-61-8C22H23NO5
N-Fmoc-N-cyclopentylglycine chemical structure, C22H23NO4, CAS 1343040-07-2
N-Fmoc-N-cyclopentylglycine
CAS 1343040-07-2C22H23NO4
2-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetic acid chemical structure, C22H23NO4, CAS 1936119-70-8
2-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetic acid
CAS 1936119-70-8C22H23NO4
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxycyclopentane-1-carboxylic acid chemical structure, C21H21NO5, CAS 369403-17-8
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxycyclopentane-1-carboxylic acid
CAS 369403-17-8C21H21NO5
3-(1,1-Dimethylethoxy)-1-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-cyclopentanecarboxylic acid chemical structure, C25H29NO5, CAS 369403-19-0
3-(1,1-Dimethylethoxy)-1-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-cyclopentanecarboxylic acid
CAS 369403-19-0C25H29NO5
(3-Hydroxy-1-hydroxymethyl-cyclopentyl)-carbamic acid 9H-fluoren-9-ylmethyl ester chemical structure, C21H23NO4, CAS 898404-79-0
(3-Hydroxy-1-hydroxymethyl-cyclopentyl)-carbamic acid 9H-fluoren-9-ylmethyl ester
CAS 898404-79-0C21H23NO4
(3-tert-Butoxy-1-hydroxymethyl-cyclopentyl)-carbamic acid 9H-fluoren-9-ylmethyl ester chemical structure, C25H31NO4, CAS 898404-81-4
(3-tert-Butoxy-1-hydroxymethyl-cyclopentyl)-carbamic acid 9H-fluoren-9-ylmethyl ester
CAS 898404-81-4C25H31NO4
2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentyl)acetic acid chemical structure, C22H23NO4, CAS 282524-99-6
2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentyl)acetic acid
CAS 282524-99-6C22H23NO4
rac-2-((1R,2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentyl)acetic acid chemical structure, C22H23NO4, CAS 1932774-91-8
rac-2-((1R,2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopentyl)acetic acid
CAS 1932774-91-8C22H23NO4
2-[(1R,2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)cyclopentyl]acetic acid chemical structure, C22H23NO4, CAS 623566-96-1
2-[(1R,2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)cyclopentyl]acetic acid
CAS 623566-96-1C22H23NO4
(9H-Fluoren-9-yl)methyl N-cyclopentyl-N-(2-hydroxyethyl)carbamate chemical structure, C22H25NO3, CAS 1340076-99-4
(9H-Fluoren-9-yl)methyl N-cyclopentyl-N-(2-hydroxyethyl)carbamate
CAS 1340076-99-4C22H25NO3
(9H-Fluoren-9-yl)methyl N-[1-(hydroxymethyl)cyclopentyl]carbamate chemical structure, C21H23NO3, CAS 1342567-12-7
(9H-Fluoren-9-yl)methyl N-[1-(hydroxymethyl)cyclopentyl]carbamate
CAS 1342567-12-7C21H23NO3