Murcko scaffold
Ring system with 4 rings and 23 atoms
33 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 33
- With full pages
- 1
Scaffold SMILES
O=C(NC1CC=CC1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 33 of 33 chemicals
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-3-ene-1-carboxylic acid
CAS 2219369-66-9C21H19NO4
![4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-ene-1-carboxylic acid chemical structure, C21H19NO4, CAS 2138342-32-0](/s/NCPGXDCNFMQHSH-UHFFFAOYSA-N.svg)
4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-ene-1-carboxylic acid
CAS 2138342-32-0C21H19NO4
(3R,4S)-4-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxycyclopentene-1-carboxylic acid
CAS 2411178-84-0C21H19NO5
![2-Ethyl-2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}butanoic acid chemical structure, C27H30N2O5, CAS 2172264-35-4](/s/DGMAHGXVPWMLJP-UHFFFAOYSA-N.svg)
2-Ethyl-2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}butanoic acid
CAS 2172264-35-4C27H30N2O5
![4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}but-2-ynoic acid chemical structure, C25H22N2O5, CAS 2171860-68-5](/s/OCYCKDFOXZEATR-UHFFFAOYSA-N.svg)
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}but-2-ynoic acid
CAS 2171860-68-5C25H22N2O5
![2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-4-methylhexanoic acid chemical structure, C28H32N2O5, CAS 2171586-29-9](/s/QMYYFMAVDNXOIS-UHFFFAOYSA-N.svg)
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-4-methylhexanoic acid
CAS 2171586-29-9C28H32N2O5
![(2S)-3-(Dimethylamino)-2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}propanoic acid chemical structure, C26H29N3O5, CAS 2171369-95-0](/s/SPRNQBQKJYINNI-VXLWULRPSA-N.svg)
(2S)-3-(Dimethylamino)-2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}propanoic acid
CAS 2171369-95-0C26H29N3O5
![(3R)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}heptanoic acid chemical structure, C28H32N2O5, CAS 2171322-42-0](/s/GXHGDPCCORJRJG-FIWHBWSRSA-N.svg)
(3R)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}heptanoic acid
CAS 2171322-42-0C28H32N2O5
![2-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}oxy)propanoic acid chemical structure, C24H24N2O6, CAS 2172343-35-8](/s/ZJMCEFZSNMFPSK-UHFFFAOYSA-N.svg)
2-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}oxy)propanoic acid
CAS 2172343-35-8C24H24N2O6
![2-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}oxy)-3-methoxypropanoic acid chemical structure, C25H26N2O7, CAS 2171992-74-6](/s/ZHVCTFJXAGWRLU-UHFFFAOYSA-N.svg)
2-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}oxy)-3-methoxypropanoic acid
CAS 2171992-74-6C25H26N2O7
![(3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hexanoic acid chemical structure, C27H30N2O5, CAS 2171379-30-7](/s/DXJHFYYQSDDSPR-OYKVQYDMSA-N.svg)
(3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hexanoic acid
CAS 2171379-30-7C27H30N2O5
![(3R)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}pentanoic acid chemical structure, C26H28N2O5, CAS 2171348-79-9](/s/MPMPPTAXEYXHIM-QNSVNVJESA-N.svg)
(3R)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}pentanoic acid
CAS 2171348-79-9C26H28N2O5
![3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-4,4,4-trifluorobutanoic acid chemical structure, C25H23F3N2O5, CAS 2172165-12-5](/s/YUVIWVLQDIIZRQ-UHFFFAOYSA-N.svg)
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-4,4,4-trifluorobutanoic acid
CAS 2172165-12-5C25H23F3N2O5
![2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}acetic acid chemical structure, C23H22N2O5, CAS 2171974-31-3](/s/XKVGLASTOHNHHE-UHFFFAOYSA-N.svg)
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}acetic acid
CAS 2171974-31-3C23H22N2O5
![3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-2-hydroxy-2-methylpropanoic acid chemical structure, C25H26N2O6, CAS 2171893-18-6](/s/VBZXUSYQXGMWHJ-UHFFFAOYSA-N.svg)
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-2-hydroxy-2-methylpropanoic acid
CAS 2171893-18-6C25H26N2O6
![(3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}pentanoic acid chemical structure, C26H28N2O5, CAS 2171307-84-7](/s/MPMPPTAXEYXHIM-ZENAZSQFSA-N.svg)
(3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}pentanoic acid
CAS 2171307-84-7C26H28N2O5
![(3R)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hexanoic acid chemical structure, C27H30N2O5, CAS 2171421-12-6](/s/DXJHFYYQSDDSPR-MRTLOADZSA-N.svg)
(3R)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hexanoic acid
CAS 2171421-12-6C27H30N2O5
![2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hex-4-ynoic acid chemical structure, C27H26N2O5, CAS 2171619-19-3](/s/HYSXUCMUAKIJLD-UHFFFAOYSA-N.svg)
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hex-4-ynoic acid
CAS 2171619-19-3C27H26N2O5
![(3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}heptanoic acid chemical structure, C28H32N2O5, CAS 2171413-74-2](/s/GXHGDPCCORJRJG-XJDOXCRVSA-N.svg)
(3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}heptanoic acid
CAS 2171413-74-2C28H32N2O5
![2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-3,3,3-trifluoropropanoic acid chemical structure, C24H21F3N2O5, CAS 2171604-06-9](/s/PPYWWQQAPYQLEJ-UHFFFAOYSA-N.svg)
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-3,3,3-trifluoropropanoic acid
CAS 2171604-06-9C24H21F3N2O5
![3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}heptanoic acid chemical structure, C28H32N2O5, CAS 2172006-59-4](/s/GXHGDPCCORJRJG-UHFFFAOYSA-N.svg)
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}heptanoic acid
CAS 2172006-59-4C28H32N2O5
![3-{1-[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]-N-propylformamido}propanoic acid chemical structure, C27H30N2O5, CAS 2172243-54-6](/s/QQIZKYLECNVNSQ-UHFFFAOYSA-N.svg)
3-{1-[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]-N-propylformamido}propanoic acid
CAS 2172243-54-6C27H30N2O5
![2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-5-methylhex-4-enoic acid chemical structure, C28H30N2O5, CAS 2171583-14-3](/s/WBZBKSYEBZAUTQ-UHFFFAOYSA-N.svg)
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-5-methylhex-4-enoic acid
CAS 2171583-14-3C28H30N2O5
![4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hexanoic acid chemical structure, C27H30N2O5, CAS 2172016-05-4](/s/NTZKJWUSOJMTRO-UHFFFAOYSA-N.svg)
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}hexanoic acid
CAS 2172016-05-4C27H30N2O5
- 4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-2-methoxybutanoic acid2172553-99-8C26H28N2O6
- (3S)-3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}butanoic acid2171376-40-0C25H26N2O5
- 4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-3,3-dimethylbutanoic acid2172106-65-7C27H30N2O5
- 2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-5-methylhexanoic acid2171621-13-7C28H32N2O5
- (2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-1-en-1-yl]formamido}-4-methoxy-4-oxobutanoic acid2648938-20-7C26H26N2O7
- (9H-Fluoren-9-yl)methyl N-[1-(hydroxymethyl)cyclopent-3-en-1-yl]carbamate2764012-15-7C21H21NO3
- (9H-Fluoren-9-yl)methyl N-[1-(prop-2-en-1-yl)cyclopent-3-en-1-yl]carbamate2770545-85-0C23H23NO2
- 1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3,4-dimethylcyclopent-3-ene-1-carboxylic acid2920153-27-9C23H23NO4
- (3S,4R)-4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxycyclopent-1-ene-1-carboxylic acid2913158-53-7C21H19NO5
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NC1CCCC1)OCC1c2ccccc2-c2ccccc2115 chemicals
O=C(NC1CCNC1)OCC1c2ccccc2-c2ccccc218 chemicals
O=C(NC1CCOC1)OCC1c2ccccc2-c2ccccc215 chemicals![Scaffold O=C(Nc1cn[nH]c1)OCC1c2ccccc2-c2ccccc21](/scaffold/GRYNIMLLGMUFHI-UHFFFAOYSA-N/structure.svg)
O=C(Nc1cn[nH]c1)OCC1c2ccccc2-c2ccccc214 chemicals
O=C(NC1CCNC1=O)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(Nc1ccn[nH]1)OCC1c2ccccc2-c2ccccc21](/scaffold/FLEVPWMMBRYGKK-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccn[nH]1)OCC1c2ccccc2-c2ccccc212 chemicals![Scaffold O=C(NN=Cc1cn[nH]c1)C1c2ccccc2-c2ccccc21](/scaffold/GTQCBQXRCMODFH-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1cn[nH]c1)C1c2ccccc2-c2ccccc212 chemicals
c1ccc2c(c1)c1ccccc1n2CCCNC1CCCC11 chemical
O=C(NN=Cc1ccco1)C1c2ccccc2-c2ccccc211 chemical
O=C(Nc1ccsc1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(NC1C=CCC1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O1 chemical