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Murcko scaffold

Ring system with 4 rings and 23 atoms

139 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
139
With full pages
1
Scaffold SMILES

O=C(NC1C=CCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1C=CCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 139 chemicals

4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-2-ene-1-carboxylic acid chemical structure, C21H19NO4, CAS 929976-63-6
4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-2-ene-1-carboxylic acid
CAS 929976-63-6C21H19NO4
(1R,4S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-2-enecarboxylic acid chemical structure, C21H19NO4, CAS 220497-65-4
(1R,4S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-2-enecarboxylic acid
CAS 220497-65-4C21H19NO4
(1S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-2-enecarboxylic acid chemical structure, C21H19NO4, CAS 220497-64-3
(1S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-2-enecarboxylic acid
CAS 220497-64-3C21H19NO4
(1S,4S)-4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-ene-1-carboxylic acid chemical structure, C21H19NO4, CAS 2639377-73-2
(1S,4S)-4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-ene-1-carboxylic acid
CAS 2639377-73-2C21H19NO4
cis-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)cyclopent-3-ene-1-carboxylic acid chemical structure, C21H19NO4, CAS 1212278-30-2
cis-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)cyclopent-3-ene-1-carboxylic acid
CAS 1212278-30-2C21H19NO4
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-3,3-dimethylbutanoic acid chemical structure, C27H30N2O5, CAS 2171688-56-3
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-3,3-dimethylbutanoic acid
CAS 2171688-56-3C27H30N2O5
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2,2-difluoropropanoic acid chemical structure, C24H22F2N2O5, CAS 2171825-73-1
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2,2-difluoropropanoic acid
CAS 2171825-73-1C24H22F2N2O5
(2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-3-hydroxypropanoic acid chemical structure, C24H24N2O6, CAS 2648920-85-6
(2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-3-hydroxypropanoic acid
CAS 2648920-85-6C24H24N2O6
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4,4-dimethylpentanoic acid chemical structure, C28H32N2O5, CAS 2172017-14-8
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4,4-dimethylpentanoic acid
CAS 2172017-14-8C28H32N2O5
2-{N-Ethyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-methylpropanoic acid chemical structure, C27H30N2O5, CAS 2172520-44-2
2-{N-Ethyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-methylpropanoic acid
CAS 2172520-44-2C27H30N2O5
2-{1-[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]-N-propylformamido}acetic acid chemical structure, C26H28N2O5, CAS 2172521-54-7
2-{1-[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]-N-propylformamido}acetic acid
CAS 2172521-54-7C26H28N2O5
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-methylbutanoic acid chemical structure, C26H28N2O5, CAS 2172520-28-2
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-methylbutanoic acid
CAS 2172520-28-2C26H28N2O5
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4,4-difluorobutanoic acid chemical structure, C25H24F2N2O5, CAS 2171775-39-4
2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4,4-difluorobutanoic acid
CAS 2171775-39-4C25H24F2N2O5
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2,2-dimethylbutanoic acid chemical structure, C27H30N2O5, CAS 2171901-52-1
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2,2-dimethylbutanoic acid
CAS 2171901-52-1C27H30N2O5
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-methylbutanoic acid chemical structure, C26H28N2O5, CAS 2172110-68-6
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-methylbutanoic acid
CAS 2172110-68-6C26H28N2O5
(2R)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}pentanoic acid chemical structure, C26H28N2O5, CAS 2648933-55-3
(2R)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}pentanoic acid
CAS 2648933-55-3C26H28N2O5
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-hydroxypropanoic acid chemical structure, C24H24N2O6, CAS 2172384-36-8
3-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-2-hydroxypropanoic acid
CAS 2172384-36-8C24H24N2O6
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}butanoic acid chemical structure, C25H26N2O5, CAS 2172512-52-4
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}butanoic acid
CAS 2172512-52-4C25H26N2O5
2-{N-tert-Butyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}acetic acid chemical structure, C27H30N2O5, CAS 2171869-90-0
2-{N-tert-Butyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}acetic acid
CAS 2171869-90-0C27H30N2O5
(2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4-methylpentanoic acid chemical structure, C27H30N2O5, CAS 2648928-50-9
(2S)-2-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4-methylpentanoic acid
CAS 2648928-50-9C27H30N2O5
2-{N-[2-(Dimethylamino)ethyl]-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}acetic acid chemical structure, C27H31N3O5, CAS 2172193-94-9
2-{N-[2-(Dimethylamino)ethyl]-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}acetic acid
CAS 2172193-94-9C27H31N3O5
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4-methylpentanoic acid chemical structure, C27H30N2O5, CAS 2171937-97-4
4-{[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}-4-methylpentanoic acid
CAS 2171937-97-4C27H30N2O5
3-{N-Ethyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}butanoic acid chemical structure, C27H30N2O5, CAS 2172141-39-6
3-{N-Ethyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}butanoic acid
CAS 2172141-39-6C27H30N2O5
2-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}methyl)pentanoic acid chemical structure, C27H30N2O5, CAS 2172121-74-1
2-({[4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopent-2-en-1-yl]formamido}methyl)pentanoic acid
CAS 2172121-74-1C27H30N2O5