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Murcko scaffold

Ring system with 2 rings and 10 atoms

48 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
48
With full pages
7
Scaffold SMILES

c1csc(-n2cccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(-n2cccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,5-dimethyl-3-thiophenecarbonitrile chemical structure, C13H14N2S, CAS 340319-53-1
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,5-dimethyl-3-thiophenecarbonitrile
CAS 340319-53-1C13H14N2S
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carboxylic acid chemical structure, C13H15NO2S, CAS 432530-64-8
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carboxylic acid
CAS 432530-64-8C13H15NO2S
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carbohydrazide chemical structure, C13H17N3OS, CAS 330452-06-7
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carbohydrazide
CAS 330452-06-7C13H17N3OS
4,5-Dimethyl-2-(1H-pyrrol-1-yl)thiophene-3-carboxylic acid chemical structure, C11H11NO2S, CAS 26176-19-2
4,5-Dimethyl-2-(1H-pyrrol-1-yl)thiophene-3-carboxylic acid
CAS 26176-19-2C11H11NO2S
Ethyl 2-(2,5-dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carboxylate chemical structure, C15H19NO2S, CAS 352444-96-3
Ethyl 2-(2,5-dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carboxylate
CAS 352444-96-3C15H19NO2S
2-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)-4,5-dimethyl-3-thiophenecarboxylic acid chemical structure, C14H15NO3S, CAS 827009-72-3
2-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)-4,5-dimethyl-3-thiophenecarboxylic acid
CAS 827009-72-3C14H15NO3S
Dimethyl 5-(2,5-dimethyl-1H-pyrrol-1-yl)-3-(2-methoxy-2-oxoethyl)-2,4-thiophenedicarboxylate chemical structure, C17H19NO6S, CAS 339020-23-4
Dimethyl 5-(2,5-dimethyl-1H-pyrrol-1-yl)-3-(2-methoxy-2-oxoethyl)-2,4-thiophenedicarboxylate
CAS 339020-23-4C17H19NO6S
3-[2-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-thienyl]-3-oxopropanenitrile chemical structure, C13H12N2OS, CAS 478078-01-2
3-[2-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-thienyl]-3-oxopropanenitrile
CAS 478078-01-2C13H12N2OS
Ethyl 4-cyano-5-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methylthiophene-2-carboxylate chemical structure, C15H16N2O2S, CAS 690643-36-8
Ethyl 4-cyano-5-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methylthiophene-2-carboxylate
CAS 690643-36-8C15H16N2O2S
5-(2,5-Dimethylpyrrol-1-yl)thiophene-2-carbohydrazide chemical structure, C11H13N3OS, CAS 380427-09-8
5-(2,5-Dimethylpyrrol-1-yl)thiophene-2-carbohydrazide
CAS 380427-09-8C11H13N3OS
N,N,5-trimethyl-2-pyrrol-1-ylthiophene-3-carboxamide chemical structure, C12H14N2OS, CAS 681459-99-4
N,N,5-trimethyl-2-pyrrol-1-ylthiophene-3-carboxamide
CAS 681459-99-4C12H14N2OS
5-Methyl-2-pyrrol-1-yl-thiophene-3-carboxylic acid chemical structure, C10H9NO2S, CAS 151258-67-2
5-Methyl-2-pyrrol-1-yl-thiophene-3-carboxylic acid
CAS 151258-67-2C10H9NO2S
Methyl 2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-thiophenecarboxylate chemical structure, C12H13NO2S, CAS 478077-85-9
Methyl 2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-thiophenecarboxylate
CAS 478077-85-9C12H13NO2S
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-thiophenecarboxylic acid chemical structure, C11H11NO2S, CAS 478077-98-4
2-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-thiophenecarboxylic acid
CAS 478077-98-4C11H11NO2S
2-(2,5-Dimethyl-1H-1-pyrrolyl)-3-thiophenecarbohydrazide chemical structure, C11H13N3OS, CAS 678139-53-2
2-(2,5-Dimethyl-1H-1-pyrrolyl)-3-thiophenecarbohydrazide
CAS 678139-53-2C11H13N3OS
2-(1H-Pyrrol-1-yl)thiophene-3-carbonitrile chemical structure, C9H6N2S, CAS 63647-03-0
2-(1H-Pyrrol-1-yl)thiophene-3-carbonitrile
CAS 63647-03-0C9H6N2S
5-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-methylthiophene-2-carbohydrazide chemical structure, C12H15N3OS, CAS 885458-80-0
5-(2,5-Dimethyl-1H-pyrrol-1-yl)-3-methylthiophene-2-carbohydrazide
CAS 885458-80-0C12H15N3OS
2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophene-3-carbonitrile chemical structure, C11H10N2S, CAS 338777-45-0
2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophene-3-carbonitrile
CAS 338777-45-0C11H10N2S
2-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carbonitrile chemical structure, C14H14N2OS, CAS 340319-64-4
2-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carbonitrile
CAS 340319-64-4C14H14N2OS
4,5-Dimethyl-2-(1H-pyrrol-1-yl)thiophene-3-carbonitrile chemical structure, C11H10N2S, CAS 138300-40-0
4,5-Dimethyl-2-(1H-pyrrol-1-yl)thiophene-3-carbonitrile
CAS 138300-40-0C11H10N2S
N'-Hydroxy-2-(1H-pyrrol-1-yl)-3-thiophenecarboximidamide chemical structure, C9H9N3OS, CAS 866041-04-5
N'-Hydroxy-2-(1H-pyrrol-1-yl)-3-thiophenecarboximidamide
CAS 866041-04-5C9H9N3OS
3-Thiophenamine, 2-(1H-pyrrol-1-yl)- chemical structure, C8H8N2S, CAS 79257-10-6
3-Thiophenamine, 2-(1H-pyrrol-1-yl)-
CAS 79257-10-6C8H8N2S
2-(2-Formyl-1H-pyrrol-1-yl)thiophene-3-carbonitrile chemical structure, C10H6N2OS, CAS 68593-68-0
2-(2-Formyl-1H-pyrrol-1-yl)thiophene-3-carbonitrile
CAS 68593-68-0C10H6N2OS
[2-(1H-Pyrrol-1-yl)thiophen-3-yl]methanamine chemical structure, C9H10N2S, CAS 63647-04-1
[2-(1H-Pyrrol-1-yl)thiophen-3-yl]methanamine
CAS 63647-04-1C9H10N2S