Murcko scaffold
1,8-Naphthyridin-4-ol scaffold
136 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 136
- With full pages
- 18
Scaffold SMILES
O=c1cc[nH]c2ncccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1cc[nH]c2ncccc12](/scaffold/NQUIRWXTTAMWIU-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 136 chemicals
Nalidixic acid
CAS 389-08-2C12H12N2O3
Ethyl 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate
CAS 33331-59-8C14H16N2O3
Citrated nalidixic acid
CAS 79449-95-9C18H17N2Na3O10
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine
CAS 10299-49-7C11H12N2O
Hydroxynalidixic acid
CAS 3759-18-0C12H12N2O4
7-Carboxynalidixic acid
CAS 1088-16-0C12H10N2O5
N-(4-Oxo-1H-1,8-naphthyridin-2-yl)acetamide
CAS 6959-01-9C10H9N3O2
![1-[2-[(1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carbonyl)amino]propanoylamino]ethylphosphonic acid chemical structure, C17H23N4O6P, CAS 81070-52-2](/s/SUCWFTPCPCRUIQ-UHFFFAOYSA-N.svg)
1-[2-[(1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carbonyl)amino]propanoylamino]ethylphosphonic acid
CAS 81070-52-2C17H23N4O6P
![Diethyl (1-{[N-(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbonyl)alanyl]amino}ethyl)phosphonate chemical structure, C21H31N4O6P, CAS 83165-74-6](/s/NWCHQOVHKBYSNP-UHFFFAOYSA-N.svg)
Diethyl (1-{[N-(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbonyl)alanyl]amino}ethyl)phosphonate
CAS 83165-74-6C21H31N4O6P
1-Ethyl-7-methyl-6-nitro-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 24677-82-5C12H11N3O5
1,8-Naphthyridin-4-ol
CAS 54569-29-8C8H6N2O
Methyl 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
CAS 63475-29-6C13H14N2O3
1-Ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide
CAS 79878-27-6C12H14N4O2
Ethyl 7-chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
CAS 79286-86-5C13H12ClFN2O3
Nalidixate sodium anhydrous
CAS 3374-05-8C12H11N2NaO3
Ethyl 6-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
CAS 339064-69-6C11H9ClN2O3
2-Acetamido-5-hydroxy-1,8-naphthyridine
CAS 5350-37-8C10H9N3O2
Ethyl 7-amino-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
CAS 5350-39-0C11H11N3O3
4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid
CAS 13250-97-0C10H8N2O3
7-Methyl-1,8-naphthyridin-4(1H)-one
CAS 49655-73-4C9H8N2O
Ethyl 7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate
CAS 35482-56-5C12H12N2O3
Ethyl 5-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
CAS 397845-42-0C12H12N2O3
2,7-Dimethyl-1,8-naphthyridin-4-ol
CAS 1439401-17-8C10H10N2O
1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carbonyl chloride
CAS 52377-28-3C12H11ClN2O2
- Ethyl 6-bromo-4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate91570-88-6C12H11BrN2O3
- Ethyl 4-hydroxy-6-iodo-7-methyl[1,8]naphthyridine-3-carboxylate361533-43-9C12H11IN2O3
- 7-Methyl-4-oxo-1H-1,8-naphthyridine-3-carbonitrile56412-89-6C10H7N3O
- 1 suppliers7-Amino-1,8-naphthyridin-4-ol17592-94-8C8H7N3O
- Ethyl 7-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate57773-26-9C13H14N2O3
- 3,7-Dimethyl-1,8-naphthyridin-4(1H)-one53052-49-6C10H10N2O
- Ethyl 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate127720-04-1C11H10N2O3
- 4-Oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid37976-17-3C9H6N2O3
- 8-Ethyl-5,8-dihydro-6-nitro-5-oxo-1,8-naphthyridine-2-carboxylic acid70186-34-4C11H9N3O5
- 1 suppliers3-Bromo-1,8-naphthyridin-4-ol58708-43-3C8H5BrN2O
- 3-Chloro-1,8-naphthyridin-4-ol72235-37-1C8H5ClN2O
- 7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid79286-73-0C11H8ClFN2O3
- 7-Chloro-4-hydroxy-[1,8]naphthyridine-3-carboxylic acid ethyl ester83785-66-4C11H9ClN2O3
- Ethyl 7-chloro-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate56654-05-8C13H13ClN2O3
- 3-Amino-1-ethyl-7-methyl-1,8-naphthyridin-4(1H)-one79878-28-7C11H13N3O
- Ethyl 6-ethoxy-4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate73101-81-2C14H16N2O4
- Ethyl 6-ethoxy-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate73101-82-3C16H20N2O4
- Ethyl 1,4-dihydro-6-ethoxy-1-ethyl-7-formyl-4-oxo-1,8-naphthyridine-3-carboxylate73101-83-4C16H18N2O5
- Ethyl 1,4-dihydro-1-ethyl-7-formyl-6-hydroxy-4-oxo-1,8-naphthyridine-3-carboxylate1429376-71-5C14H14N2O5
- 3-Chloro-2,7-dimethyl-1,4-dihydro-1,8-naphthyridin-4-one87436-35-9C10H9ClN2O
- Ethyl 7-(ethylthio)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate84424-21-5C13H13FN2O3S
- 1,8-Naphthyridin-4-ol, 7-methyl-2-propyl-718624-73-8C12H14N2O
- Ethyl 1-ethyl-7-ethylsulfonyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate79286-90-1C15H17FN2O5S
- 7-Chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid54563-42-7C9H5ClN2O3
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