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Murcko scaffold

1,5-Naphthyridin-4-ol scaffold

92 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
92
With full pages
4
Scaffold SMILES

O=c1cc[nH]c2cccnc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,5-Naphthyridin-4-ol page
Murcko scaffold O=c1cc[nH]c2cccnc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 92 chemicals

4-Hydroxy-1,5-naphthyridine-3-carboxylic acid chemical structure, C9H6N2O3, CAS 53512-10-0
4-Hydroxy-1,5-naphthyridine-3-carboxylic acid
CAS 53512-10-0C9H6N2O3
1,5-Naphthyridin-4-ol chemical structure, C8H6N2O, CAS 5423-54-1
1,5-Naphthyridin-4-ol
CAS 5423-54-1C8H6N2O
3-Carbethoxy-4-hydroxy-6-methyl-1,5-naphthyridine chemical structure, C12H12N2O3, CAS 5000-81-7
3-Carbethoxy-4-hydroxy-6-methyl-1,5-naphthyridine
CAS 5000-81-7C12H12N2O3
6-Methyl-1,5-naphthyridin-4-ol chemical structure, C9H8N2O, CAS 23443-24-5
6-Methyl-1,5-naphthyridin-4-ol
CAS 23443-24-5C9H8N2O
3-Carboxy-4-hydroxy-6-methoxy-1,5-naphthyridine chemical structure, C10H8N2O4, CAS 220861-33-6
3-Carboxy-4-hydroxy-6-methoxy-1,5-naphthyridine
CAS 220861-33-6C10H8N2O4
Ethyl 4-hydroxy-6-methoxy-1,5-naphthyridine-3-carboxylate chemical structure, C12H12N2O4, CAS 53241-92-2
Ethyl 4-hydroxy-6-methoxy-1,5-naphthyridine-3-carboxylate
CAS 53241-92-2C12H12N2O4
6-Chloro-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylic acid chemical structure, C9H5ClN2O3, CAS 959277-17-9
6-Chloro-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylic acid
CAS 959277-17-9C9H5ClN2O3
Ethyl 6-chloro-4-hydroxy[1,5]naphthyridine-3-carboxylate chemical structure, C11H9ClN2O3, CAS 127094-58-0
Ethyl 6-chloro-4-hydroxy[1,5]naphthyridine-3-carboxylate
CAS 127094-58-0C11H9ClN2O3
Ethyl 6-ethoxy-1,4-dihydro-4-oxo-1,5-naphthyridine-3-carboxylate chemical structure, C13H14N2O4, CAS 92808-33-8
Ethyl 6-ethoxy-1,4-dihydro-4-oxo-1,5-naphthyridine-3-carboxylate
CAS 92808-33-8C13H14N2O4
2-Methyl-6-methoxy-1,5-naphthyridin-4-ol chemical structure, C10H10N2O2, CAS 872801-99-5
2-Methyl-6-methoxy-1,5-naphthyridin-4-ol
CAS 872801-99-5C10H10N2O2
3-Bromo[1,5]naphthyridin-4-ol chemical structure, C8H5BrN2O, CAS 113518-92-6
3-Bromo[1,5]naphthyridin-4-ol
CAS 113518-92-6C8H5BrN2O
Ethyl 4-hydroxy-1,5-naphthyridine-3-carboxylate chemical structure, C11H10N2O3, CAS 13801-51-9
Ethyl 4-hydroxy-1,5-naphthyridine-3-carboxylate
CAS 13801-51-9C11H10N2O3
6-Methoxy-1,5-naphthyridin-4-ol chemical structure, C9H8N2O2, CAS 23443-25-6
6-Methoxy-1,5-naphthyridin-4-ol
CAS 23443-25-6C9H8N2O2
2-Methyl-1,5-naphthyridin-4(1H)-one chemical structure, C9H8N2O, CAS 10261-83-3
2-Methyl-1,5-naphthyridin-4(1H)-one
CAS 10261-83-3C9H8N2O
Ethyl 8-methoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylate chemical structure, C12H12N2O4, CAS 64761-20-2
Ethyl 8-methoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylate
CAS 64761-20-2C12H12N2O4
1-Ethyl-1,5-naphthyridin-4(1H)-one chemical structure, C10H10N2O, CAS 79426-15-6
1-Ethyl-1,5-naphthyridin-4(1H)-one
CAS 79426-15-6C10H10N2O
6-Ethoxy-4-hydroxy-1,5-naphthyridine-3-carboxylic acid chemical structure, C11H10N2O4, CAS 92808-09-8
6-Ethoxy-4-hydroxy-1,5-naphthyridine-3-carboxylic acid
CAS 92808-09-8C11H10N2O4
Ethyl 7-bromo-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylate chemical structure, C11H9BrN2O3, CAS 64436-97-1
Ethyl 7-bromo-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylate
CAS 64436-97-1C11H9BrN2O3
7-Bromo-4-hydroxy-1,5-naphthyridine-3-carboxylic acid chemical structure, C9H5BrN2O3, CAS 97267-59-9
7-Bromo-4-hydroxy-1,5-naphthyridine-3-carboxylic acid
CAS 97267-59-9C9H5BrN2O3
7-Bromo-1,5-naphthyridin-4-ol chemical structure, C8H5BrN2O, CAS 97267-60-2
7-Bromo-1,5-naphthyridin-4-ol
CAS 97267-60-2C8H5BrN2O
7-(Trifluoromethyl)-1,5-naphthyridin-4-ol chemical structure, C9H5F3N2O, CAS 130291-17-7
7-(Trifluoromethyl)-1,5-naphthyridin-4-ol
CAS 130291-17-7C9H5F3N2O
6-Ethoxy-4-hydroxy-1,5-naphthyridine-3-carbonitrile chemical structure, C11H9N3O2, CAS 305370-97-2
6-Ethoxy-4-hydroxy-1,5-naphthyridine-3-carbonitrile
CAS 305370-97-2C11H9N3O2
4-Hydroxy-1,5-naphthyridine-3-carbonitrile chemical structure, C9H5N3O, CAS 305371-00-0
4-Hydroxy-1,5-naphthyridine-3-carbonitrile
CAS 305371-00-0C9H5N3O
2-Ethyl-6-methoxy-1,5-naphthyridin-4(1H)-one chemical structure, C11H12N2O2, CAS 135900-10-6
2-Ethyl-6-methoxy-1,5-naphthyridin-4(1H)-one
CAS 135900-10-6C11H12N2O2