CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
40
With full pages
3
Scaffold SMILES

O=C(CSc1ccccc1)Nc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccccc1)Nc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

Ethyl 5-ethyl-2-{[(phenylsulfanyl)acetyl]amino}-3-thiophenecarboxylate chemical structure, C17H19NO3S2, CAS 309286-81-5
Ethyl 5-ethyl-2-{[(phenylsulfanyl)acetyl]amino}-3-thiophenecarboxylate
CAS 309286-81-5C17H19NO3S2
Ethyl 4,5-dimethyl-2-{[(phenylsulfanyl)acetyl]amino}-3-thiophenecarboxylate chemical structure, C17H19NO3S2, CAS 309286-80-4
Ethyl 4,5-dimethyl-2-{[(phenylsulfanyl)acetyl]amino}-3-thiophenecarboxylate
CAS 309286-80-4C17H19NO3S2
Methyl 4,5-dimethyl-2-(2-phenylthioacetylamino)thiophene-3-carboxylate chemical structure, C16H17NO3S2, CAS 379245-41-7
Methyl 4,5-dimethyl-2-(2-phenylthioacetylamino)thiophene-3-carboxylate
CAS 379245-41-7C16H17NO3S2
Methylethyl 5-methyl-2-(2-phenylthioacetylamino)thiophene-3-carboxylate chemical structure, C17H19NO3S2, CAS 524928-82-3
Methylethyl 5-methyl-2-(2-phenylthioacetylamino)thiophene-3-carboxylate
CAS 524928-82-3C17H19NO3S2
Ethyl 5-acetyl-2-({[(4-chlorophenyl)sulfanyl]acetyl}amino)-4-methyl-3-thiophenecarboxylate chemical structure, C18H18ClNO4S2, CAS 665017-12-9
Ethyl 5-acetyl-2-({[(4-chlorophenyl)sulfanyl]acetyl}amino)-4-methyl-3-thiophenecarboxylate
CAS 665017-12-9C18H18ClNO4S2
2-[2-[(3-Ethoxycarbonyl-4,5-dimethylthiophen-2-yl)amino]-2-oxoethyl]sulfanylbenzoic acid chemical structure, C18H19NO5S2, CAS 5301-94-0
2-[2-[(3-Ethoxycarbonyl-4,5-dimethylthiophen-2-yl)amino]-2-oxoethyl]sulfanylbenzoic acid
CAS 5301-94-0C18H19NO5S2
Ethyl 5-acetyl-4-methyl-2-({[(4-methylphenyl)sulfanyl]acetyl}amino)thiophene-3-carboxylate chemical structure, C19H21NO4S2, CAS 663211-72-1
Ethyl 5-acetyl-4-methyl-2-({[(4-methylphenyl)sulfanyl]acetyl}amino)thiophene-3-carboxylate
CAS 663211-72-1C19H21NO4S2
Diethyl 5-(2-((4-chlorophenyl)thio)acetamido)-3-methylthiophene-2,4-dicarboxylate chemical structure, C19H20ClNO5S2, CAS 403843-91-4
Diethyl 5-(2-((4-chlorophenyl)thio)acetamido)-3-methylthiophene-2,4-dicarboxylate
CAS 403843-91-4C19H20ClNO5S2
2-(2-(Phenylthio)acetamido)thiophene-3-carboxamide chemical structure, C13H12N2O2S2, CAS 771501-19-0
2-(2-(Phenylthio)acetamido)thiophene-3-carboxamide
CAS 771501-19-0C13H12N2O2S2
2-(4-Acetamidophenyl)sulfanyl-N-(3-cyanothiophen-2-yl)acetamide chemical structure, C15H13N3O2S2, CAS 851631-26-0
2-(4-Acetamidophenyl)sulfanyl-N-(3-cyanothiophen-2-yl)acetamide
CAS 851631-26-0C15H13N3O2S2
N-(3-Cyanothiophen-2-yl)-2-[3-(trifluoromethyl)phenyl]sulfanylacetamide chemical structure, C14H9F3N2OS2, CAS 338777-47-2
N-(3-Cyanothiophen-2-yl)-2-[3-(trifluoromethyl)phenyl]sulfanylacetamide
CAS 338777-47-2C14H9F3N2OS2
4,5-Dimethyl-2-(2-phenylthioacetylamino)thiophene-3-carboxamide chemical structure, C15H16N2O2S2, CAS 830340-02-8
4,5-Dimethyl-2-(2-phenylthioacetylamino)thiophene-3-carboxamide
CAS 830340-02-8C15H16N2O2S2
2-[(4-Chlorophenyl)sulfanyl]-N-(3-cyano-4,5-dimethylthiophen-2-yl)acetamide chemical structure, C15H13ClN2OS2, CAS 689743-82-6
2-[(4-Chlorophenyl)sulfanyl]-N-(3-cyano-4,5-dimethylthiophen-2-yl)acetamide
CAS 689743-82-6C15H13ClN2OS2
2-(3-Chlorophenyl)sulfanyl-N-(3-cyanothiophen-2-yl)acetamide chemical structure, C13H9ClN2OS2, CAS 338777-38-1
2-(3-Chlorophenyl)sulfanyl-N-(3-cyanothiophen-2-yl)acetamide
CAS 338777-38-1C13H9ClN2OS2
Diethyl 5-(2-((4-chlorophenyl)thio)propanamido)-3-methylthiophene-2,4-dicarboxylate chemical structure, C20H22ClNO5S2, CAS 403843-92-5
Diethyl 5-(2-((4-chlorophenyl)thio)propanamido)-3-methylthiophene-2,4-dicarboxylate
CAS 403843-92-5C20H22ClNO5S2
Ethyl 4-carbamoyl-3-methyl-5-{[(phenylsulfanyl)acetyl]amino}thiophene-2-carboxylate chemical structure, C17H18N2O4S2, CAS 445007-29-4
Ethyl 4-carbamoyl-3-methyl-5-{[(phenylsulfanyl)acetyl]amino}thiophene-2-carboxylate
CAS 445007-29-4C17H18N2O4S2
Methyl 4,5-dimethyl-2-({[(pentafluorophenyl)sulfanyl]acetyl}amino)thiophene-3-carboxylate chemical structure, C16H12F5NO3S2, CAS 515849-56-6
Methyl 4,5-dimethyl-2-({[(pentafluorophenyl)sulfanyl]acetyl}amino)thiophene-3-carboxylate
CAS 515849-56-6C16H12F5NO3S2
Ethyl 3-methyl-5-(2-(p-tolylthio)acetamido)thiophene-2-carboxylate chemical structure, C17H19NO3S2, CAS 895457-17-7
Ethyl 3-methyl-5-(2-(p-tolylthio)acetamido)thiophene-2-carboxylate
CAS 895457-17-7C17H19NO3S2
Methyl 2-[[2-(4-methylphenyl)sulfanylacetyl]amino]thiophene-3-carboxylate chemical structure, C15H15NO3S2, CAS 895458-55-6
Methyl 2-[[2-(4-methylphenyl)sulfanylacetyl]amino]thiophene-3-carboxylate
CAS 895458-55-6C15H15NO3S2
Ethyl 2-(2-(p-tolylthio)acetamido)thiophene-3-carboxylate chemical structure, C16H17NO3S2, CAS 895458-63-6
Ethyl 2-(2-(p-tolylthio)acetamido)thiophene-3-carboxylate
CAS 895458-63-6C16H17NO3S2
2-(2-(p-Tolylthio)acetamido)thiophene-3-carboxamide chemical structure, C14H14N2O2S2, CAS 895458-70-5
2-(2-(p-Tolylthio)acetamido)thiophene-3-carboxamide
CAS 895458-70-5C14H14N2O2S2
N-Methyl-2-(2-(p-tolylthio)acetamido)thiophene-3-carboxamide chemical structure, C15H16N2O2S2, CAS 895458-78-3
N-Methyl-2-(2-(p-tolylthio)acetamido)thiophene-3-carboxamide
CAS 895458-78-3C15H16N2O2S2
2-(2-((4-Chlorophenyl)thio)acetamido)thiophene-3-carboxamide chemical structure, C13H11ClN2O2S2, CAS 879623-57-1
2-(2-((4-Chlorophenyl)thio)acetamido)thiophene-3-carboxamide
CAS 879623-57-1C13H11ClN2O2S2
2-(2-((4-Chlorophenyl)thio)acetamido)-N-methylthiophene-3-carboxamide chemical structure, C14H13ClN2O2S2, CAS 895472-95-4
2-(2-((4-Chlorophenyl)thio)acetamido)-N-methylthiophene-3-carboxamide
CAS 895472-95-4C14H13ClN2O2S2