Murcko scaffold
N-Phenylpyrrolidine-1-carboxamide scaffold
193 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 193
- With full pages
- 17
Scaffold SMILES
O=C(Nc1ccccc1)N1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 193 chemicals
1-Pyrrolidinecarboxamide, N-(4-chlorophenyl)-
CAS 35640-09-6C11H13ClN2O
1-Pyrrolidinecarboxanilide, 3'-chloro-3-(diethylamino)-, monohydrochloride
CAS 20984-71-8C15H23Cl2N3O
1-Pyrrolidinecarboxy-m-toluidide, 3-(diethylamino)-alpha,alpha,alpha-trifluoro-, monohydrochloride
CAS 20984-72-9C16H23ClF3N3O
1-Pyrrolidinecarboxanilide, 3-(diethylamino)-N-methyl-, monohydrochloride
CAS 23456-27-1C16H26ClN3O
1-Pyrrolidinecarboxanilide, 2'-hydroxy-
CAS 24638-13-9C11H14N2O2
N-(3-Nitrophenyl)pyrrolidine-1-carboxamide
CAS 35799-28-1C11H13N3O3
![1-[(4-Fluorophenyl)carbamoyl]pyrrolidine-2-carboxylic acid chemical structure, C12H13FN2O3, CAS 1009519-24-7](/s/CYVTYTNYTQOEDD-UHFFFAOYSA-N.svg)
1-[(4-Fluorophenyl)carbamoyl]pyrrolidine-2-carboxylic acid
CAS 1009519-24-7C12H13FN2O3
![D-Proline, 1-[(phenylamino)carbonyl]- chemical structure, C12H14N2O3, CAS 827612-78-2](/s/ZEEAHHXBZHTCOI-SNVBAGLBSA-N.svg)
D-Proline, 1-[(phenylamino)carbonyl]-
CAS 827612-78-2C12H14N2O3
N-(3-Chlorophenyl)-1-pyrrolidinecarboxamide
CAS 35640-07-4C11H13ClN2O
Pyrrolidine-1-carboxylic acid (3,4-dichloro-phenyl)-amide
CAS 35640-08-5C11H12Cl2N2O
N-Phenylpyrrolidine-1-carboxamide
CAS 5626-53-9C11H14N2O
Methyl 2-(pyrrolidine-1-carboxamido)benzoate
CAS 708241-16-1C13H16N2O3
N-(4-Methylphenyl)pyrrolidine-1-carboxamide
CAS 35938-95-5C12H16N2O
N-(2-Fluorophenyl)pyrrolidine-1-carboxamide
CAS 853750-82-0C11H13FN2O
2-Chloro-4-(pyrrolidine-1-carboxamido)benzene-1-sulfonyl chloride
CAS 680617-79-2C11H12Cl2N2O3S
3-Chloro-4-(pyrrolidine-1-carboxamido)benzene-1-sulfonyl chloride
CAS 678185-86-9C11H12Cl2N2O3S
![2-Ethoxy-5-[(pyrrolidine-1-carbonyl)-amino]-benzenesulfonyl chloride chemical structure, C13H17ClN2O4S, CAS 680618-12-6](/s/KYVQCVBMLZMRKL-UHFFFAOYSA-N.svg)
2-Ethoxy-5-[(pyrrolidine-1-carbonyl)-amino]-benzenesulfonyl chloride
CAS 680618-12-6C13H17ClN2O4S
4-Ethoxy-3-(pyrrolidine-1-carboxamido)benzene-1-sulfonyl chloride
CAS 678186-09-9C13H17ClN2O4S
4-(Pyrrolidine-1-carbonylamino)benzenesulfonyl chloride
CAS 677326-96-4C11H13ClN2O3S
![Methyl 1-[(3,4-dichloroanilino)carbonyl]-4-hydroxy-2-pyrrolidinecarboxylate chemical structure, C13H14Cl2N2O4, CAS 318247-31-3](/s/APXIFYRYSQKXML-UHFFFAOYSA-N.svg)
Methyl 1-[(3,4-dichloroanilino)carbonyl]-4-hydroxy-2-pyrrolidinecarboxylate
CAS 318247-31-3C13H14Cl2N2O4
N-(4-Chloro-3-nitrophenyl)pyrrolidine-1-carboxamide
CAS 680212-55-9C11H12ClN3O3
![Methyl 4-hydroxy-1-{[3-(trifluoromethyl)anilino]carbonyl}-2-pyrrolidinecarboxylate chemical structure, C14H15F3N2O4, CAS 318247-30-2](/s/FFANPHGIUWHMOR-UHFFFAOYSA-N.svg)
Methyl 4-hydroxy-1-{[3-(trifluoromethyl)anilino]carbonyl}-2-pyrrolidinecarboxylate
CAS 318247-30-2C14H15F3N2O4
1-(Phenylcarbamoyl)proline
CAS 73096-22-7C12H14N2O3
N-(4-Nitrophenyl)pyrrolidine-1-carboxamide
CAS 35799-21-4C11H13N3O3
- N-(5-Chloro-2-methoxyphenyl)pyrrolidine-1-carboxamide701282-17-9C12H15ClN2O2
- N-(4-Sulfamoylphenyl)pyrrolidine-1-carboxamide838868-88-5C11H15N3O3S
- N-(3-Methylphenyl)pyrrolidine-1-carboxamide35799-26-9C12H16N2O
- N-(4-Fluorophenyl)pyrrolidine-1-carboxamide84882-83-7C11H13FN2O
- 1-Pyrrolidinecarboxamide, N-(3,4,5-trimethoxyphenyl)-68060-93-5C14H20N2O4
- 1-(3-Chloro-phenylcarbamoyl)-pyrrolidine-2-carboxylic acid674299-59-3C12H13ClN2O3
- N1-(4-Ethoxyphenyl)-N2-(1-methylethyl)-1,2-pyrrolidinedicarboxamide1008930-81-1C17H25N3O3
- Methyl 1-(anilinocarbonyl)-4-hydroxy-2-pyrrolidinecarboxylate183290-11-1C13H16N2O4
- 1-(N-(2,4-Xylyl)carbamoyl)pyrrolidine35938-97-7C13H18N2O
- Pyrrolidine-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide35640-10-9C12H13F3N2O
- N-(4-Bromo-2-chlorophenyl)pyrrolidine-1-carboxamide885412-52-2C11H12BrClN2O
- N-(4-Ethoxyphenyl)pyrrolidine-1-carboxamide36879-56-8C13H18N2O2
- N-(3-Chloro-2-methylphenyl)pyrrolidine-1-carboxamide893024-88-9C12H15ClN2O
- N-(3-Chloro-4-fluorophenyl)pyrrolidine-1-carboxamide904871-26-7C11H12ClFN2O
- N-(2-Ethylphenyl)pyrrolidine-1-carboxamide899021-98-8C13H18N2O
- N-(3,4-Dimethylphenyl)pyrrolidine-1-carboxamide890332-55-5C13H18N2O
- N-(2,3-Dimethylphenyl)pyrrolidine-1-carboxamide904119-00-2C13H18N2O
- N-(4-Bromophenyl)pyrrolidine-1-carboxamide904475-25-8C11H13BrN2O
- N-(3,5-Dimethylphenyl)pyrrolidine-1-carboxamide900700-29-0C13H18N2O
- N-(4-Ethylphenyl)pyrrolidine-1-carboxamide903026-14-2C13H18N2O
- N-(2,4-Difluorophenyl)pyrrolidine-1-carboxamide893019-25-5C11H12F2N2O
- N-(3-Fluorophenyl)pyrrolidine-1-carboxamide905626-49-5C11H13FN2O
- Ethyl 4-(pyrrolidinylcarbonylamino)benzoate881473-90-1C14H18N2O3
- N-(3-Chloro-4-methylphenyl)-1-pyrrolidinecarboxamide853319-17-2C12H15ClN2O
Related scaffolds
Same ring framework with different atoms or bond orders
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c1ccc(OCc2ccco2)cc175 chemicals
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c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
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O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals