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Murcko scaffold

Pyridylisoxazole scaffold

105 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
105
With full pages
7
Scaffold SMILES

c1ccc(-c2ccon2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyridylisoxazole page
Murcko scaffold c1ccc(-c2ccon2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 105 chemicals

Isoxazole, 5-(2-(dimethylamino)ethyl)-3-(2-pyridyl)-, citrate chemical structure, C18H23N3O8, CAS 14732-53-7
Isoxazole, 5-(2-(dimethylamino)ethyl)-3-(2-pyridyl)-, citrate
CAS 14732-53-7C18H23N3O8
Isoxazole, 5-(2-(diethylamino)ethyl)-3-(2-pyridyl)-, citrate chemical structure, C20H27N3O8, CAS 14732-54-8
Isoxazole, 5-(2-(diethylamino)ethyl)-3-(2-pyridyl)-, citrate
CAS 14732-54-8C20H27N3O8
3-(2-Pyridinyl)-5-isoxazolemethanol chemical structure, C9H8N2O2, CAS 158840-78-9
3-(2-Pyridinyl)-5-isoxazolemethanol
CAS 158840-78-9C9H8N2O2
3-Pyridin-2-ylisoxazole-5-carboxylic acid methyl ester chemical structure, C10H8N2O3, CAS 330558-58-2
3-Pyridin-2-ylisoxazole-5-carboxylic acid methyl ester
CAS 330558-58-2C10H8N2O3
Ethyl 3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-5-methyl-1,2-oxazole-4-carboxylate chemical structure, C13H10ClF3N2O3, CAS 303997-38-8
Ethyl 3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-5-methyl-1,2-oxazole-4-carboxylate
CAS 303997-38-8C13H10ClF3N2O3
Methyl 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-5-methyl-4-isoxazolecarboxylate chemical structure, C12H8ClF3N2O3, CAS 303997-60-6
Methyl 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-5-methyl-4-isoxazolecarboxylate
CAS 303997-60-6C12H8ClF3N2O3
Phosphonic acid, (3-(2-pyridinyl)-5-isoxazolyl)-, diammonium salt chemical structure, C8H13N4O4P, CAS 125674-66-0
Phosphonic acid, (3-(2-pyridinyl)-5-isoxazolyl)-, diammonium salt
CAS 125674-66-0C8H13N4O4P
5-Methyl-3-(pyridin-2-yl)-1,2-oxazole-4-carboxylic acid chemical structure, C10H8N2O3, CAS 842958-49-0
5-Methyl-3-(pyridin-2-yl)-1,2-oxazole-4-carboxylic acid
CAS 842958-49-0C10H8N2O3
1-{3-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-5-isoxazolyl}-1-ethanol chemical structure, C11H8ClF3N2O2, CAS 477872-98-3
1-{3-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-5-isoxazolyl}-1-ethanol
CAS 477872-98-3C11H8ClF3N2O2
1-{3-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-5-isoxazolyl}-1-ethanone chemical structure, C11H6ClF3N2O2, CAS 477872-99-4
1-{3-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-5-isoxazolyl}-1-ethanone
CAS 477872-99-4C11H6ClF3N2O2
3-Chloro-2-[5-(1-chloroethyl)-3-isoxazolyl]-5-(trifluoromethyl)pyridine chemical structure, C11H7Cl2F3N2O, CAS 439097-50-4
3-Chloro-2-[5-(1-chloroethyl)-3-isoxazolyl]-5-(trifluoromethyl)pyridine
CAS 439097-50-4C11H7Cl2F3N2O
(E)-1-[3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl]-3-(dimethylamino)prop-2-en-1-one chemical structure, C14H11ClF3N3O2, CAS 551930-72-4
(E)-1-[3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl]-3-(dimethylamino)prop-2-en-1-one
CAS 551930-72-4C14H11ClF3N3O2
2-(5-Iodo-3-isoxazolyl)pyridine chemical structure, C8H5IN2O, CAS 393165-18-9
2-(5-Iodo-3-isoxazolyl)pyridine
CAS 393165-18-9C8H5IN2O
Pyridine, 2-[5-[(trimethylsilyl)ethynyl]-3-isoxazolyl]- chemical structure, C13H14N2OSi, CAS 393165-19-0
Pyridine, 2-[5-[(trimethylsilyl)ethynyl]-3-isoxazolyl]-
CAS 393165-19-0C13H14N2OSi
2-(5-Methyl-1,2-oxazol-3-yl)pyridine chemical structure, C9H8N2O, CAS 85903-31-7
2-(5-Methyl-1,2-oxazol-3-yl)pyridine
CAS 85903-31-7C9H8N2O
5-(Chloromethyl)-3-(pyridin-2-yl)isoxazole chemical structure, C9H7ClN2O, CAS 130114-08-8
5-(Chloromethyl)-3-(pyridin-2-yl)isoxazole
CAS 130114-08-8C9H7ClN2O
4-Methyl-3-(pyridin-2-yl)-1,2-oxazol-5-amine chemical structure, C9H9N3O, CAS 909132-93-0
4-Methyl-3-(pyridin-2-yl)-1,2-oxazol-5-amine
CAS 909132-93-0C9H9N3O
Pyridylisoxazole chemical structure, C8H6N2O, CAS 1594907-83-1
Pyridylisoxazole
CAS 1594907-83-1C8H6N2O
3-(3-Fluoro-2-pyridyl)-5-methylisoxazole-4-carboxylic Acid chemical structure, C10H7FN2O3, CAS 471909-56-5
3-(3-Fluoro-2-pyridyl)-5-methylisoxazole-4-carboxylic Acid
CAS 471909-56-5C10H7FN2O3
Ethyl 5-Methyl-3-(2-pyridyl)isoxazole-4-carboxylate chemical structure, C12H12N2O3, CAS 954230-43-4
Ethyl 5-Methyl-3-(2-pyridyl)isoxazole-4-carboxylate
CAS 954230-43-4C12H12N2O3
3-(3-(Pyridin-2-yl)isoxazol-5-yl)prop-2-yn-1-ol chemical structure, C11H8N2O2, CAS 545421-88-3
3-(3-(Pyridin-2-yl)isoxazol-5-yl)prop-2-yn-1-ol
CAS 545421-88-3C11H8N2O2
1-(3-(Pyridin-2-yl)isoxazol-5-yl)ethanone chemical structure, C10H8N2O2, CAS 889939-02-0
1-(3-(Pyridin-2-yl)isoxazol-5-yl)ethanone
CAS 889939-02-0C10H8N2O2
1-(3-Pyridin-2-ylisoxazol-5-yl)methanamine chemical structure, C9H9N3O, CAS 543713-45-7
1-(3-Pyridin-2-ylisoxazol-5-yl)methanamine
CAS 543713-45-7C9H9N3O
3-(Pyridin-2-yl)isoxazole-5-carboxylic acid chemical structure, C9H6N2O3, CAS 716362-11-7
3-(Pyridin-2-yl)isoxazole-5-carboxylic acid
CAS 716362-11-7C9H6N2O3