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Murcko scaffold

1-[3-(Morpholin-4-yl)phenyl]piperazine scaffold

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
15
With full pages
3
Scaffold SMILES

c1cc(N2CCNCC2)cc(N2CCOCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[3-(Morpholin-4-yl)phenyl]piperazine page
Murcko scaffold c1cc(N2CCNCC2)cc(N2CCOCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

4-(2-Nitro-5-piperazin-1-ylphenyl)morpholine chemical structure, C14H20N4O3, CAS 332023-13-9
4-(2-Nitro-5-piperazin-1-ylphenyl)morpholine
CAS 332023-13-9C14H20N4O3
2-[4-(5-Morpholin-4-yl-2-nitrophenyl)piperazin-1-yl]ethanol chemical structure, C16H24N4O4, CAS 327050-76-0
2-[4-(5-Morpholin-4-yl-2-nitrophenyl)piperazin-1-yl]ethanol
CAS 327050-76-0C16H24N4O4
2-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]ethanol chemical structure, C16H24N4O4, CAS 311785-18-9
2-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]ethanol
CAS 311785-18-9C16H24N4O4
4-[5-(4-Methylsulfonylpiperazin-1-yl)-2-nitrophenyl]morpholine chemical structure, C15H22N4O5S, CAS 346704-12-9
4-[5-(4-Methylsulfonylpiperazin-1-yl)-2-nitrophenyl]morpholine
CAS 346704-12-9C15H22N4O5S
RefChem:381789 chemical structure, C15H23ClN4O3, CAS 5813-68-3
RefChem:381789
CAS 5813-68-3C15H23ClN4O3
4-[5-(4-Ethylsulfonylpiperazin-1-yl)-2-nitrophenyl]morpholine chemical structure, C16H24N4O5S, CAS 433238-99-4
4-[5-(4-Ethylsulfonylpiperazin-1-yl)-2-nitrophenyl]morpholine
CAS 433238-99-4C16H24N4O5S
2,2-Dimethyl-1-[4-(3-morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]propan-1-one chemical structure, C19H28N4O4, CAS 642430-12-4
2,2-Dimethyl-1-[4-(3-morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]propan-1-one
CAS 642430-12-4C19H28N4O4
N,N-Dimethyl-4-(3-morpholin-4-yl-4-nitrophenyl)piperazine-1-sulfonamide chemical structure, C16H25N5O5S, CAS 591736-59-3
N,N-Dimethyl-4-(3-morpholin-4-yl-4-nitrophenyl)piperazine-1-sulfonamide
CAS 591736-59-3C16H25N5O5S
2-Methyl-1-[4-(3-morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]propan-1-one chemical structure, C18H26N4O4, CAS 662164-18-3
2-Methyl-1-[4-(3-morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]propan-1-one
CAS 662164-18-3C18H26N4O4
1-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]propan-1-one chemical structure, C17H24N4O4, CAS 714208-23-8
1-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]propan-1-one
CAS 714208-23-8C17H24N4O4
1-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]butan-1-one chemical structure, C18H26N4O4, CAS 765922-25-6
1-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]butan-1-one
CAS 765922-25-6C18H26N4O4
1-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]ethanone chemical structure, C16H22N4O4, CAS 893764-80-2
1-[4-(3-Morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]ethanone
CAS 893764-80-2C16H22N4O4
1-[3-(Morpholin-4-yl)phenyl]piperazine chemical structure, C14H21N3O, CAS 350047-46-0
1-[3-(Morpholin-4-yl)phenyl]piperazine
CAS 350047-46-0C14H21N3O
1-Acetyl-4-(4-amino-3-morpholin-4-ylphenyl)piperazine chemical structure, C16H24N4O2, CAS 931583-58-3
1-Acetyl-4-(4-amino-3-morpholin-4-ylphenyl)piperazine
CAS 931583-58-3C16H24N4O2
tert-Butyl 4-(3-amino-5-morpholinophenyl)piperazine-1-carboxylate chemical structure, C19H30N4O3, CAS 1051899-49-0
tert-Butyl 4-(3-amino-5-morpholinophenyl)piperazine-1-carboxylate
CAS 1051899-49-0C19H30N4O3