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Murcko scaffold

2,6-Di(phenyl)-4-piperidone scaffold

59 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
59
With full pages
15
Scaffold SMILES

O=C1CC(c2ccccc2)NC(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,6-Di(phenyl)-4-piperidone page
Murcko scaffold O=C1CC(c2ccccc2)NC(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

1-Methyl-2,6-diphenylpiperidin-4-one chemical structure, C18H19NO, CAS 39653-65-1
1-Methyl-2,6-diphenylpiperidin-4-one
CAS 39653-65-1C18H19NO
1,3-Dimethyl-2,6-diphenylpiperidin-4-one chemical structure, C19H21NO, CAS 5554-58-5
1,3-Dimethyl-2,6-diphenylpiperidin-4-one
CAS 5554-58-5C19H21NO
4-Piperidinone, 2,6-bis(4-methoxyphenyl)-3-methyl- chemical structure, C20H23NO3, CAS 138453-07-3
4-Piperidinone, 2,6-bis(4-methoxyphenyl)-3-methyl-
CAS 138453-07-3C20H23NO3
3,5-Dimethyl-2,6-diphenyl-4-piperidinone chemical structure, C19H21NO, CAS 5707-11-9
3,5-Dimethyl-2,6-diphenyl-4-piperidinone
CAS 5707-11-9C19H21NO
1,3,5-Trimethyl-2,6-diphenylpiperidin-4-one chemical structure, C20H23NO, CAS 5554-59-6
1,3,5-Trimethyl-2,6-diphenylpiperidin-4-one
CAS 5554-59-6C20H23NO
2,6-Bis(4-methoxyphenyl)-3,5-dimethylpiperidin-4-one chemical structure, C21H25NO3, CAS 151454-11-4
2,6-Bis(4-methoxyphenyl)-3,5-dimethylpiperidin-4-one
CAS 151454-11-4C21H25NO3
Diethyl 1-methyl-4-oxo-2,6-diphenyl-piperidine-3,5-dicarboxylate chemical structure, C24H27NO5, CAS 7153-69-7
Diethyl 1-methyl-4-oxo-2,6-diphenyl-piperidine-3,5-dicarboxylate
CAS 7153-69-7C24H27NO5
2,6-Diphenyl-3-propylpiperidin-4-one chemical structure, C20H23NO, CAS 127895-87-8
2,6-Diphenyl-3-propylpiperidin-4-one
CAS 127895-87-8C20H23NO
(2R,6S)-2,6-Diphenylpiperidin-4-one chemical structure, C17H17NO, CAS 54750-61-7
(2R,6S)-2,6-Diphenylpiperidin-4-one
CAS 54750-61-7C17H17NO
3,5-Diethyl-2,6-diphenylpiperidin-4-one chemical structure, C21H25NO, CAS 102596-94-1
3,5-Diethyl-2,6-diphenylpiperidin-4-one
CAS 102596-94-1C21H25NO
3-Methyl-2,6-bis(4-nitrophenyl)-4-piperidinone chemical structure, C18H17N3O5, CAS 17040-73-2
3-Methyl-2,6-bis(4-nitrophenyl)-4-piperidinone
CAS 17040-73-2C18H17N3O5
2,6-Di(phenyl)-4-piperidone chemical structure, C17H17NO, CAS 5554-55-2
2,6-Di(phenyl)-4-piperidone
CAS 5554-55-2C17H17NO
3-Isopropyl-2,6-diphenyl-piperidin-4-one chemical structure, C20H23NO, CAS 79246-08-5
3-Isopropyl-2,6-diphenyl-piperidin-4-one
CAS 79246-08-5C20H23NO
3-Ethyl-2,6-diphenylpiperidin-4-one chemical structure, C19H21NO, CAS 127895-86-7
3-Ethyl-2,6-diphenylpiperidin-4-one
CAS 127895-86-7C19H21NO
1-Methyl-3-pentyl-2,6-diphenylpiperidin-4-one chemical structure, C23H29NO, CAS 127895-89-0
1-Methyl-3-pentyl-2,6-diphenylpiperidin-4-one
CAS 127895-89-0C23H29NO
1-Ethyl-3,5-dimethyl-2,6-diphenylpiperidin-4-one chemical structure, C21H25NO, CAS 306947-41-1
1-Ethyl-3,5-dimethyl-2,6-diphenylpiperidin-4-one
CAS 306947-41-1C21H25NO
2,6-Bis(3-bromophenyl)-3,5-dimethylpiperidin-4-one chemical structure, C19H19Br2NO, CAS 471261-83-3
2,6-Bis(3-bromophenyl)-3,5-dimethylpiperidin-4-one
CAS 471261-83-3C19H19Br2NO
2,6-Bis(4-chlorophenyl)-3,5-dimethylpiperidin-4-one chemical structure, C19H19Cl2NO, CAS 134645-35-5
2,6-Bis(4-chlorophenyl)-3,5-dimethylpiperidin-4-one
CAS 134645-35-5C19H19Cl2NO
3,5-Dimethyl-2,6-bis(3-methylphenyl)piperidin-4-one chemical structure, C21H25NO, CAS 1005138-05-5
3,5-Dimethyl-2,6-bis(3-methylphenyl)piperidin-4-one
CAS 1005138-05-5C21H25NO
1-Piperidinecarboxamide, 2,6-bis(p-methoxyphenyl)-N-ethyl-3-methyl-4-oxo- chemical structure, C23H28N2O4, CAS 101997-62-0
1-Piperidinecarboxamide, 2,6-bis(p-methoxyphenyl)-N-ethyl-3-methyl-4-oxo-
CAS 101997-62-0C23H28N2O4
3,5-Dimethyl-2,6-bis(4-methylphenyl)-4-piperidinone chemical structure, C21H25NO, CAS 151454-12-5
3,5-Dimethyl-2,6-bis(4-methylphenyl)-4-piperidinone
CAS 151454-12-5C21H25NO
3,5-Dimethyl-2,6-bis(4-nitrophenyl)piperidin-4-one chemical structure, C19H19N3O5, CAS 171084-96-1
3,5-Dimethyl-2,6-bis(4-nitrophenyl)piperidin-4-one
CAS 171084-96-1C19H19N3O5
4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl- chemical structure, C20H23NO, CAS 64292-65-5
4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl-
CAS 64292-65-5C20H23NO
2,6-Bis(4-methoxyphenyl)-3-(propan-2-yl)piperidin-4-one chemical structure, C22H27NO3, CAS 5806-19-9
2,6-Bis(4-methoxyphenyl)-3-(propan-2-yl)piperidin-4-one
CAS 5806-19-9C22H27NO3